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Insulin

Total questions: 13

Worksheet time: 8mins

Name
Class
Date
1.

Insulin are classified according to?


I. Type

II. Onset

III. Duration

IV. Mechanism of action

a)

I and II

b)

I, II and III

c)

II and III

d)

I and IV

2.

I) Rapid acting insulin - Humulin R

II) Short acting insulin - Humulin N

III) Intermediate acting insulin - Novolin N

IV) Long acting insulin - Insulin detemir


Which pairs are correct?

a)

I

b)

II and IV

c)

III and IV

d)

All above

3.

Short acting insulins are the only insulin tat may be IV.

a)

True

b)

False

4.

Concurrent use of thiazide diuretics and glucocorticoids may raise blood glucose level and thereby counteract the effects of insulin.

a)

True

b)

False

5.

All classification of oral hypoglycemic agents control blood glucose levels in clients with Type 1 diabetes mellitus.

a)

True

b)

False

6.

State 5 oral hypoglycemic medications.

(a)  

7.

X block ATP-sensitive K+ channels. What is X?

a)

Meglitinides

b)

Crocodile

c)

Sulfonylureas

d)

Thiazolidinediones (TZD)

8.

Which OHA lower insulin resistance by acting as AGONISTS for the peroxisome proliferator-activated receptor- y (a nuclear hormone receptor)

a)

Alpha glucosdase inhibitor (acarbose)

b)

Meglitinides (Repaglinide)

c)

Biaguanides (Metformin HCL)

d)

Thiazolidinediones (Rosiglitazone, pioglitazone)

9.

The incretin mimetic are analogs of GLP-1 that exert their activity by acting as GLP-1 receptor agonists. It....

a)

Improve glucose-dependent insulin secretipn

b)

Slow gastric emptying time

c)

Decrease postprandial glucagon secretion

d)

Promote B-cell proliferation

10.

Which OHA drugs have an adverse effects on GI?

I. Glipizide

II. Metformin HCL

III. Acarbose

IV. Tolbutamide

a)

I only

b)

II and III

c)

I and IV

d)

All above

11.

Hyperglycemic agent glucagon is a drug used for emergency management of hypoglycemic reactions (insulin overdose). This medication is pregnancy risk category A.

a)

True

b)

False

12.

Ben is a patient with Type 2 diabetes who has a blood glucose of 400 md/dl today at his office visit.The physician would like to give some insulin to bring the glucose down before he leaves the office. Which of the following would lower the glucose in the quickest manner in Ben?

a)

Insulin aspart

b)

Insulin glargine

c)

NPH insulin

d)

Regular insulin

13.

Which of the following classes of oral diabetes drugs is paired most appropriately with its primary mechanism of action?

a)

DDP-4 inhibitor : inhibits breakdown of complex carbohydrates

b)

Glinide : increases insulin sensitivity

c)

Sulfonylurea : increases insulin secretion

d)

Thiazolidinedione : decreases hepatic gluconeogenesis