WorksheetsAcute Coronary Syndrome & Cardiac Biomarkers
Total questions: 6
Worksheet time: 2mins
A patient presented with a complaint of central chest pain, no ST elevation with elevated cardiac biomarkers, what is the possible diagnosis?
STEMI
NSTEMI
UA
None of the above, he is healthy!
Which of the following is true about cardiac troponin?
Troponins have a high clinical sensitivity and near absolute specificity for myocardial necrosis.
It peaks at 6 hours.
It is not useful for the detection of reinfarction.
It remains elevated for less than 24 hours.
Which of the following is false about CK-MB?
CK-MB is a more sensitive and specific test for myocardial damage than total CK
The plasma mass measurement method of CK-MB is the best alternatives.
Remains the gold standard cardiac biomarker.
A 20% or more increase in the value of CK-MB between 2 samples 3-6 hours apart support the diagnosis of reinfarction.
Which of the following is true about myoglobin?
This appears slowly after myocardial necrosis but has not achieved widespread use in cardiac practice.
Myoglobin can only be found in muscle tissue and would be present in the bloodstream if there is damaged muscle tissue.
Rises in the first 30 minutes and slowly excreted from the kidneys.
Since it has no specificity, positive values are important rather than negative values.
Which of the following is false about LDH?
Expressed in many organs including skeletal muscle, kidney, liver, heart, and lungs.
Increases within 6-12 hours from onset of chest pain.
Peaks over 5-7 days.
Returns to normal within 8-14 days
Which of the following is true about AST?
A different group with ALT.
In cardiac and skeletal muscle, ALT is 20 times more than AST.
Declining over 2-3 days if no further cardiac damage.
AST is a specific and sensitive marker for the diagnosis of MI.
