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Apoptosis, Cancer, and stem cell

Total questions: 23

Worksheet time: 21mins

Name
Class
Date
1.

A cell is known to respond to a particular signalling molecule. Which of the following must be true of this cell?

a)

It is in the heart muscle.

b)

It is also the site of the production for the signalling molecule.

c)

It contains the receptor for the signalling molecule.

d)

It is incapable of signal transduction.

2.

Give the correct sequence of apoptosis:

1. Nucleus begins to break

2. Nucleus condensation and formation of bleb

3. Phagocytosis of apoptotic bodies.

a)

1, 2, 3

b)

2, 3, 1

c)

3, 2, 1

d)

2,1,3

3.

What is Apoptosis?

a)

Cell programmed Death

b)

Inflammation of cell

c)

Phagocytosis

d)

Plasmolysis

4.

what could be the cause for a cell to undergo apoptosis?

a)

DNA damage

b)

Radiation

c)

Nutrient deficiency

d)

All of the above

5.

Apoptosis can't kill which of the following?

a)

Cell infected with viruses

b)

Cell with DNA damage

c)

Cancer cells

d)

Immune cells

6.

Which of the following cell organelle actively participates in animal apoptosis?

a)

Nucleus

b)

Mitochondria

c)

Lysosomes

d)

Vacuoles

7.

The apoptosome activates upon the release of what?

a)

Caspase 9

b)

Caspase 8

c)

Cytochrome c

d)

Apaf-1

8.

Which apoptotic pathway involves the Fas ligand interaction with the Fas receptor?

a)

Intrinsic apoptotic pathway

b)

Extrinsic apoptotic pathway

c)

None of the above

9.

Cancer is the uncontrolled growth and division of cell.

a)

TRUE

b)

FALSE

10.
Cancer creates abnormal cells by disrupting
a)
the cell cycle
b)
red blood cell formation
c)
DNA replication
d)
ATP synthesis
11.
An abnormal mass of cancer cells is called a 
a)
tumor
b)
cyst
c)
lesion
d)
polyp
12.
Metastasis is
a)
the spread of cancer from one part of the body to another.
b)
the growth of tumors in the lungs
c)
cancer of the blood cells
d)
cancer that is found in connective tissues
13.

Cancer cells can multiply in which situations?

a)

Presence of growth factors

b)

Absence of growth factors

c)

Signals that prevent cell division

d)

None of the above

14.

Cancer may emerge when both of the tumor-suppressor genes are _____

a)

activated

b)

inactivated

c)

enhanced

15.
Stem cells are
a)
cells that grow uncontrollably
b)
undifferentiated and can be any type of cell
c)
never go through cell division
d)
only found in embryos
16.
What does "pluripotent" mean?
a)
able to divide and make many different types of cells
b)
not able to divide
c)
can only divide and make one cell type 
d)
if it divides, it will make a cancerous tumor
17.
What process best explains how muscle cells and nerve cells can develop from the same fertilized egg?
a)
genetic engineering
b)
survival of the fittest
c)
differentiation
d)
selective breeding
18.
What is the difference between embryonic stem cells and adult stem cells?
a)
Embryonic stem cells can differentiate into more cell types than adult stem cells
b)
Adult stem cells are pluripotent, just like embryonic stem cells
c)
Adult stem cells can differentiate into more cell types than embryonic stem cells
d)
Adult stem cells grow bigger than embryonic stem cells
19.
Which is true about embryonic stem cells?
a)
They no longer divide, their cell type is set and cannot change.
b)
They can develop into only one type of cell.
c)
They can become any cell type in the body.
d)
They are found in adults.
20.
Which type of cell is unspecialized?
a)
skin cell
b)
stem cell
c)
liver cell
d)
muscle cell
21.
Which is true about Adult Stem Cells.
a)
They no longer do mitosis, their cell type is set and can not change
b)
They are limited to the type of  cell they can become.
c)
They can become any cell type in the body
d)
They are found in embryos
22.
Which of the following cells is UNdifferentiated or UNspecialized?
a)
cardiac muscle cell
b)
nerve cell
c)
liver cell
d)
stem cell
23.
What does "multipotent" mean?
a)
able to divide and make one kind of cell
b)
able to divide and make all different types of cells
c)
able to divide and make multiple (but not all) types of cells 
d)
cannot divide