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IB Biology SL Topic 3 Pretest

Total questions: 25

Worksheet time: 17mins

Name
Class
Date
1.
Which of the following is the cause of sickle-cell anemia?
a)
Tryptophan is replaced by leucine
b)
Leucine is replaced by valine
c)
Glutamic acid is replaced by valine
d)
Lysine is replaced by glutamic acid
2.
What is the cause of sickle-cell anemia?
a)
A change to the base sequence of a hemoglobin gene
b)
Mosquitos acting as the vector for malaria
c)
Iron deficiency due to the malaria parasite
d)
Production of more white blood cells than red blood cells by bone marrow
3.
A human cell has between 20,000-25,000 genes whereas an E. coli cell has approximately 4,000 genes.  Which of the following statements is true?
a)
The human genome is larger than the E. coli genome
b)
There are more genes on each human chromosome than on the E. coli chromosome
c)
The human cell and the E. coli cell produce approximately the same variety of proteins
d)
The DNA in both organisms is associated with histones (proteins)
4.
Which of the following statements about homologous chromosomes is correct?
a)
Each gene is at the same locus on both chromosomes
b)
They are two identical copies of a parent chromosome which are attached to one another at the centromere
c)
They always produce identical phenotypes
d)
They are chromosomes that have identical genes and alleles
5.
What happens in crossing over?
a)
Exchange of genes during metaphase of mitosis
b)
Random distribution of chromosomes during meiosis
c)
Exchange of genetic material between homologous chromosomes
d)
Homologous chromosomes fail to separate during meiosis
6.
A cell in the testis of a male chimpanzee contains 2n=48 chromosomes.  It then undergoes meiosis.  How many molecules of DNA will be present in the nucleus of the sperm cells just after meiosis?
a)
96
b)
48
c)
24
d)
12
7.
If the haploid number of a species is 14, how many chromatids will there be in metaphase I in a dividing diploid cell?
a)
7
b)
14
c)
28
d)
56
8.
How many autosomes are there in a human sperm?
a)
1
b)
22
c)
23
d)
46
9.
If the amount of DNA in a haploid gamete is represented by X, what is the net quantity of DNA in a cell from the same organism at the start of meiosis?
a)
0.5x
b)
x
c)
2x
d)
4x
10.
In the diagram, which pair represents homologous chromosomes?
a)
1 and 2
b)
3 and 4
c)
2 and 5
d)
4 and 6
11.
Which of the following types of information are needed to construct a karyotype?  
I
.  Size of the chromosomes
 
II
. Gene mutations of the chromosomes
 
III
. Age of the individual
a)
I only
b)
II only
c)
I and II
d)
I, II and III
12.
Which phase of cell division is photographed in order to make a karyotype?
a)
Anaphase of mitosis
b)
Anaphase I of meiosis
c)
Metaphase of mitosis
d)
Metaphase II of meiosis
13.
What does the karyotype below correspond to?
a)
A normal male
b)
A normal female
c)
A female with Down Syndrome
d)
A male with Down Syndrome
14.
What can be concluded from the karyotype  provided below?
a)
There was non-disjunction during meiosis in the mother.
b)
There was non-disjunction during meiosis in the father.
c)
The fetus is male.
d)
The fetus is female.
15.
Which of the following is an inherited disease that is due to a base substitution mutation in a gene?
a)
Trisomy 21
b)
Sickle cell anemia
c)
AIDS
d)
Type II Diabetes
16.

The image shows a karyogram. What information can be determined from this karyogram?

a)

The sex is female.

b)

The haploid number is 54.

c)

Disjunction occurred during meiosis.

d)

The species is not human.

17.

What distinguishes an allele from a gene?

a)

An allele is made of RNA.

b)

An allele is shorter.

c)

An allele is a variety of a gene.

d)

An allele cannot be transferred during genetic modification.

18.

The diploid number of chromosomes in humans (Homo sapiens) is 46 and the diploid number of chromosomes in rice (Oryza sativa) is 24. What does this indicate about diploid chromosome numbers?

a)

Plant species have a lower diploid number of chromosomes in animals.

b)

Members of a species have the same diploid number of chromosomes.

c)

The evolutionary progress of species is determined by the diploid number of chromosomes.

d)

The complexity of the organisms is correlated to the diploid number of chromosomes.

19.

What is characteristic of homologous chromosomes?

a)

They have an identical DNA sequence.

b)

They are of the same length in karyograms.

c)

They form pairs in prokaryotes.

d)

They carry the same alleles.

20.

What is the effect of dominant alleles?


I. They mask the effect of recessive alleles.

II. They become more frequent than recessive alleles in a population.

III. They have a joint effect with recessive alleles when characteristics are co-dominant.

a)

I only

b)

I and II only

c)

I and III only

d)

I, II and III

21.

What is a possible source of the chromosomes used for pre-natal karyotype diagnosis?

a)

The mother's lymphocytes.

b)

The mother's cheek cells.

c)

The cells from the chorionic villi.

d)

The fetal hair root cells.

22.

What causes the presence of three chromosomes 21 in Down syndrome?

a)

Crossing over

b)

Allele change

c)

Non-disjunction

d)

Gene mutation

23.

A human cell has between 20 000 and 25 000 genes whereas an E. coli cell has approximately 4000 genes. Which of the following statements is true?

a)

The human genome is larger than the E. coli genome.

b)

There are more genes on each human chromosome than on the E. coli chromosome.

c)

The human cell and the E. coli cell produce approximately the same variety of proteins.

d)

The DNA in both organisms is associated with histones (proteins).

24.

Which of the following statements about homologous chromosomes is correct?

a)

Each gene is at the same locus on both chromosomes.

b)

They are two identical copies of a parent chromosome which are attached to one another at the centromere.

c)

They always produce identical phenotypes.

d)

They are chromosomes that have identical genes and alleles.

25.
The ABO blood grouping system has alleles of IA, IB and i. What is this an example of?
a) co-dominance
b) multiple alleles
c) sex-lingage
d) polygenic traits
a)
a) only
b)
a) and b) only
c)
b) and c) only
d)
b) and d) only