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WorksheetsUnit 4: Cell Communication & the Cell Cycle
Total questions: 164
Worksheet time: 2hrs 17mins
Receptors for signal molecules __________.
can be found in the plasma membrane & in cytoplasm/nucleus
all work via protein kinases
all work by opening ion channels
are only found associated with the plasma membrane
A G protein is active when __________.
GDP replaces GTP
it is phosphorylated by protein kinase
GTP is bound to it
it is bound by its ligand and transported to the nucleus
What is the general name for an enzyme that transfers phosphate groups from ATP to a protein?
protein dehydrogenase
protein kinase
protein cyclase
protein phosphatase
The source of phosphate for a phosphorylation cascade is __________.
ATP
GTP
protein kinase
protein phosphatase
Why are phosphorylation cascades involving a series of protein kinases useful?
they always lead to the same cellular response
the number of molecules used is small and fixed
cAMP is not always readily available
they amplify the original signal
A process in which an initial change will bring about more change in the same direction.
negative feedback
positive feedback
homeostasis
neutral feedback
Which of the following is not true about homeostasis?
it is how the body maintains a constant environment
it is controlled by positive feedback loops
it is controlled by negative feedback loops
it is a characteristic of all living organisms
Which of the following is not an example of a negative feedback loop?
body maintaining a temperature of about 37°C
release of ADH to increase H2O reabsorption when dehydrated
a ripe apple releasing ethylene, which causes more ripening
heart rate increasing when exercising to deliver more O2 to cells
What do cells have in order to respond to a particular hormone?
a receptor for the hormone
nothing as any hormone can affect any cell at any time
an effector for the hormone
a plasma membrane
If a cell undergoes mitosis without cytokinesis, what will the resulting cell look like?
the cell will have more than one nucleus
the cell will completely lack a nucleus
the cell will be unusually small
the cell will have damaged chromosomes
Which of the following does not occur during mitosis?
condensation of chromatin to chromosomes
replication of DNA
separation of sister chromatids
the formation of a spindle apparatus
A cell has half as much DNA as other cells in a mitotically active tissue. What phase is it in?
G1
G2
prophase
metaphase
If the DNA of a 2n cell in the G1 phase is x, then what's the DNA of that cell in metaphase?
0.5x
x
2x
say what now?
Which of the following is not a cell cycle check point?
G1
G2
G0
M
Which of the following is an example of an internal control in the cell cycle?
PDGF
MPF = cyclin + cdk
positional inhibition
density dependent factors
Which of the following does not contribute to cancer?
proto-oncogenes mutated to stay on
tumor suppressor genes mutated to stay on
tumor suppressor genes mutated to stay off
proto-oncogenes stimulating uncontrolled cell division
Through a microscope, you can see a cell plate developing between two nuclei. What's going on?
a plant cell is in the process of cytokinesis
an animal cell is in the process of cytokinesis
an animal cell is in the S phase of the cell cycle
a bacterial cell is diving via binary fission
A feedback loop best fits which characteristic of life?
Cells
Organization
Homeostasis
Adaptation
According to the feedback loop, what does high blood sugar promote?
Insulin Release
Glucagon Release
Insulin Uptake
Glycogen Uptake
Cyclins are small proteins that bind to and activate CDK enzymes during the process of:
endocytosis
cell respiration
osmosis
mitosis
Cells can communicate with one another via:
chemical messengers
hormones
gap junctions
all of these
Does DNA replicate before or after cell replication?
before the cell divides
after the cell divides
G1 is associated with what event?
doubling of cell content
DNA replication
The beginning of mitosis
breakdown of the nuclear membrane
What is cancer?
A group of diseases characterized by no cell growth
A group of diseases caused by the failure of chromosomes to separate
A group of diseases characterized by uncontrolled cell division
A group of diseases caused by excessive replication of chromosomes
Humans have ________ pairs of chromosomes.
21
23
46
None of the above
When a cell is in late anaphase of mitosis, which of the following will we see?
chromosomes clustered tightly at the center
breaking down of the nuclear envelope
a clear area in the center of the cell
formation of two daughter nuclei
How do bacteria sense local population density?
quorum sensing
bacteria sensing
signal sensing
population sensing
Local signaling in animals is called what?
paracrine
endocrine
hormone
gap junctions
Long distance signaling in animals is called what?
paracrine
endocrine
hormone
gap junctions
Molecules that bind to membrane receptors are called what?
signals
ligands
glycoproteins
second messengers
What word means programmed cell death?
apoptosis
mitosis
Ced-9
bleb
Cells can communicate with one another via:
chemical messengers
hormones
gap junctions
all of these
A feedback loop best fits which characteristic of life?
Cells
Organization
Homeostasis
Adaptation
According to the feedback loop, what does high blood sugar promote?
Insulin Release
Glucagon Release
Insulin Uptake
Glycogen Uptake
Cells can communicate with one another via:
chemical messengers
hormones
gap junctions
all of these
Does DNA replicate before or after cell replication?
before the cell divides
after the cell divides
Tube-like structures that attach to the centromere of a chromosome
Metaphase Plate
Microtubules
Centrosome
Centrioles
Cleavage Furrow
Identify the circled structure...
Centrioles
Microtubules
Centrosome
Centromere
Cleavage Furrow
A
Kinetochore
Chromosome
Sister Chromatids
Centromere
Cleavage Furrow
C (each of these is called)
Kinetochore
Chromosome
Sister Chromatids
Centromere
Cleavage Furrow
E (whole structure)
Kinetochore
Chromosome
Sister Chromatids
Centromere
Cleavage Furrow
Kinetochore
Chromosome
Sister Chromatids
Centromere
Cleavage Furrow
G1 is associated with what event?
doubling of cell content
DNA replication
The beginning of mitosis
breakdown of the nuclear membrane
A diploid cell has ____ the number chromosomes as a haploid cell.
half
twice
one-fourth
four times
Attachment of the mitotic spindle fibers to the kinetochores is a characteristic of which stage of mitosis?
prophase
prometaphase
metaphase
anaphase
D (located ON this structure, one side)
Kinetochore
Chromosome
Sister Chromatids
Centromere
Cleavage Furrow
Cells grow, carry out normal functions, and copy their organelles.
G1
S
G2
M phase
Cells go through additional growth.
G1
S
G2
M phase
Cells undergo cell division, which involves both mitosis and cytokinesis.
G1
S
G2
M phase
Cells replicate DNA.
G1
S
G2
M phase
The G in G1 and G2 stands for _____.
gap
growth
gap/growth
none of these
Cells must pass through a critical checkpoint during which stages of the cell cycle?
G1
G2
M phase
All of these are correct.
Where does DNA synthesis happen in eukaryotic cells?
cytoplasm
mitochondria
nucleus
Golgi apparatus
What two processes make up the M stage?
fermentation & mitosis
mitosis & cytokinesis
glycolysis & cytokinesis
G1 & G2
Some scientists name the stage where cells carry out their normal functions but are unlikely to divide. The name they give this stage is _________.
G0
G1
G2
G3
To stay alive, a cell needs materials to move in and out across its membrane. As a cell grows bigger, its volume increases _____ than its surface area. At a certain point, the cell’s volume would be _____ compared to the area available for materials to move in and out.
faster / too small
faster / too large
slower / too small
slower / too large
The rate at which a particular type of cell divides is linked to the body’s need for that cell type. Skin cells are typically exposed to more damaging conditions than are liver cells. Skin cells must be replaced more often than liver cells. Therefore, which of these statements is true?
Skin cells and liver cells divide at the same rate.
Liver cells divide more often than skin cells.
Skin cells divide more often than liver cells.
Neither skin cells nor liver cells divide.
The word “cycle” in cell cycle refers to the _____ of growth, DNA duplication, and cell division that occurs in eukaryotic cells.
repetition
randomness
rapidness
retention
The word cytokinesis has the prefix cyto- that refers to a cell and the suffix -kinesis that refers to division or movement. Therefore, cytokinesis is the process where a cell’s cytoplasm _____.
divides
multiplies
increases
evaporates
A(n) _____ is a stage in the eukaryotic cell cycle at which the cell examines internal and external cues and "decides" whether or not to move forward with division.
checkpoint
chromosome
interphase
tumor
Which one is not a checkpoint?
G0 checkpoint
G1 checkpoint
G2 checkpoint
Spindle checkpoint
Checks for cell size, nutrients, growth factors, and DNA damage.
G1 checkpoint
G2 checkpoint
Spindle checkpoint
DNA polymerase
Checks for DNA damage and DNA replication completeness.
G1 checkpoint
G2 checkpoint
Spindle checkpoint
DNA polymerase
Checks for chromosome attachment to the spindle at the metaphase plate.
G1 checkpoint
G2 checkpoint
Spindle checkpoint
DNA polymerase
programmed cell death = _____
apoptosis
cancer
spindle
cytokinesis
uncontrolled cell growth = _____
apoptosis
cancer
spindle
cytokinesis
