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Gene Technology

Total questions: 11

Worksheet time: 8mins

Name
Class
Date
1.

Which of the following is a cloning vector?

a)

Gene cloning apparatus

b)

The enzyme that cuts the DNA into fragments

c)

Plasmid which is used to transfer DNA

d)

Bacteriophage that infects bacteria.

2.

What is used in step P?

a)

DNA ligase

b)

EcoRI

c)

Recombinant DNA

d)

Vector

3.

What is used in step Q?

a)

DNA ligase

b)

EcoRI

c)

Recombinant DNA

d)

Vector

4.

To begin the development of the human growth hormone gene, researchers created a cDNA library from cells in the pituitary gland. What does this library contain?

a)

Only the sequence encoding growth hormone

b)

DNA versions of all the mRNAs in the pituitary gland cells

c)

All the coding sequences in the human genome, but no introns

d)

All the coding sequences in the human genome, including introns

5.

The phrases below refer to different stages in the formation of a plasmid-carrying recombinant DNA.

I. Use restriction enzyme

II. Use DNA ligase

III. Remove plasmid from parent bacterium

IV. Introduce plasmid into a new host bacterium

a)

I, II, III, IV

b)

III, I, II, IV

c)

IV, III, II, I

d)

II, III, I, IV

6.

Which of the following is TRUE?

a)

I: d

II: b

III: c

IV: e

V: a

b)

I: a

II: b

III: d

IV: e

V: c

c)

I: d

II: b

III: c

IV: a

V: e

d)

I: a

II: b

III: d

IV: c

V: e

7.

Which of the following diagram representing the cut section of DNA by EcoRI is CORRECT?

a)

A

b)

B

c)

C

d)

D

8.

Name the enzyme P, Q, R & S. Please in such:

P:

Q:

R:

S:

4 lines
9.

A restriction enzyme breaks down bonds between the

a)

base pairs of a DNA molecule

b)

exons and introns of a DNA molecule

c)

base pairs of a DNA-RNA hybrid molecule

d)

sugar and phosphate components of a DNA molecule

10.

Which of the following is FALSE about plasmid?

a)

found in bacteria

b)

circular in shape

c)

carry few genes

d)

carry foreign genes into animal cells

11.

Write the 7 steps in cloning according to the sequence

4 lines