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WorksheetsTutoring 2/3/22
Total questions: 16
Worksheet time: 9mins
What two ends of the amino acid are used to form the peptide bond?
Carboxyl end of two amino acids
Amino and Hydrogen
Amino and R group
Carboxyl and R group
Amino and Carboxyl
One of the most important protein secondary structures is the alpha helix. This stiff coil is usually 10 or more residues long and forms due to a hydrogen bond between the carbonyl oxygen and the amide nitrogen of amino acids that are ______ residues apart?
5
4
3
2
1
You are trying to deduce the possible tertiary structure of a protein by a reading a series of coding elements (codons) found in its mRNA sequence. You notice the following sequence: leu-ile-trp-leu. Where would you predict this sequence will be found once the protein is fully folded?
Towards the interior of the protein
Towards the exterior of the protein
Forming the center of a binding site for ATP
Forming the center of a binding site for GTP
Which of these is an amino acid that has a side chain that will function as an acid in a chemical reaction and bear a negative charge at ph=7.2?
Lysine
Arginine
Asparagine
Glutamate
Threonine
Which one of these is an amino acid with an R group, whose pka is between 10-13?
Tryptophan
Asparagine
Isoleucine
Proline
Alanine
What is the main force holding together the secondary structures that form as proteins fold?
Ionic interactions
Interchain disulfide bonds
Hydrophilic and hydrophobic side-chains
Hydrophilic modifications such as adding oligosaccharides
Hydrogen bonds between various parts of the polypeptide backbone
An important structural protein is encoded by a single gene. Cellular analysis indicates that the protein is not modified in a major way following translation, yet there are different versions of the mRNA (long, short & medium-sized) that exist in different tissues such as neurons, kidney & stomach. Which of the following is most likely responsible for the different RNA transcripts?
Genomic recombination
Cytoplasmic recombination
Post-translational modification
Sorting in the Golgi
Alternative RNA Splicing
What RNA is produced by eukaryotic RNA polymerase Ill?
Most of the ribosomal RNA
All of the tRNAs and the 5S rRNA
All the mRNAs
All the processing-RNAs
All of the microRNAs
From this duplex DNA example, which sequence below represents a possible RNA transcript?
5' -GGGCATTTTAAATGC-3'
3' -CCCGTAAAATTTACG-5'
ACGGGCATTTTA
GGGGATTTTAAA
AAATTTTAGGGG
GGGCAUUUUAAA
AAAUUUUACCCC
What DNA-binding protein recognizes a specific bacterial promoter (containing a specific -35 box and -10 box) and acts a detachable subunit to bring the RNA polymerase to the promoter?
The family of Sigma factors
The repressor proteins
Two various activator proteins
The beta subunit of RNA polymerase
The tRNA binding protein that primes the binding of RNA polymerase Il
What is an important structural feature of RNA polymerase Il that is not found in RNA polymerase I or Ill?
It has 5 subunits instead of 4
It possesses the same PCNA collar observed in DNA polymerase delta
It contains a Cap structure
It has a prominent CTD tail
What mediated the Rho-independent termination of transcription in bacteria?
The Rho helicase
The Rho polymerase
The Rho endonuclease
A strong GC-rich RNA hairpin
A small AT-rich RNA hairpin
What RNA is produced by eukaryotic RNA polymerase I?
Most of the ribosomal RNA
All of the tRNAs
All of the mRNAs
All the processing-RNAs
All the microRNAs
Which one of these is an enzyme that is involved in capping a nascent RNA made by RNA Polymerase II?
Adenyl cyclase
Guanylyltransferase
Adenylate transferase
Cryptoform pyrase
Reverse transcriptase
What is the name for the AG site at the 3' end of an intron that is cut by the processing mechanism to release the intron as a lariat structure?
Intron Recognition Site
Exon Recognition Site
Splice Donor Site
Splice Acceptor Site
Branch A Site
What label indicated the 3' end of the template DNA strand?
A
B
C
D
E
