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PBS 2.2.1-2.2.2

Total questions: 24

Worksheet time: 16mins

Name
Class
Date
1.

developing a list of possible diseases or disorders based on the information you are given

a)

differential diagnosis

b)

learning objectives

c)

preliminary possibilities

2.

Kai's overwhelming energy and inability to focus can be identified as (a)   .

3.

chromosome pairs (one from each parent) having similar gene composition, size, and structure

a)

chromatid

b)

homologous chromosome

c)

centromere

d)

gene

4.

What phase of mitosis is this cell in?

a)

interphase

b)

prophase

c)

metaphase

d)

anaphase

e)

telophase

5.

What phase of mitosis is this cell in?

(a)  

6.

During _____________, chromosomes are being pulled to the cell's poles after lining up in the middle.

a)

anaphase

b)

metaphase

c)

telophase

d)

cytokinesis

e)

interphase

7.

DNA replicates during (a)   .

8.

What would happen if the DNA of a cell didn't replicate during interphase?

a)

the offspring cells would be missing a part and may not be able to perform a proper function

b)

cells can use DNA replication to share parts and they can make up for a small miss by helping each other

9.

TRUE or FALSE?

metastasis = a lump or mass of cells caused by an uncontrolled cell division

a)

true

b)

false

10.

TRUE or FALSE?

benign = tumors that are generally considered harmless and will not spread to other parts of the body if not treated

a)

true

b)

false

11.

(Write 2-3 sentences) What is an example differential diagnosis explanation that a doctor could use to explain Kai's condition to his parents?

4 lines
12.

What are some qualities of cells that doctors can look for when determining if cells are cancerous or not?

a)

cell division

b)

cell size and shape

c)

nucleus

d)

a different look from all other cells in the body

e)

arrangement

13.

These are the things that (a)   are responsible for: driving cell reactions, providing defense, building structures, transportation, cellular activities, and movement.

14.

The NF1 gene is found on chromosome 17 and carries the instructions to create a protein called neurofibromin. Neurofibromin regulates mitosis and works to prevent cells from growing and dividing in an uncontrolled way. The cells of individuals with NF1 divide out of control, leading to the creation of tumors. Given this information, which functional category would this protein best belong to?

a)

cellular activities because the body can keep the cells from dividing more than needed and maintains homeostasis

b)

movement because homeostasis is being maintained in the easiest and most possible way that it can without causing too much harm to the body

c)

transportation because the cells from mitosis can help control growth

d)

providing defense because the body can control the overproduction and fight

e)

building structures because the structure of this gene helps the foundation of the protection

15.

DNA ---> Proteins ---> (a)  

16.

Within a cell, DNA is housed in the ______________.

a)

nucleus

b)

ribosome

c)

cytoplasm

d)

nucleic acid

17.

TRUE or FALSE:

translation, transcription

a)

true

b)

false

18.

A, T, G, C are (a)   bases.

19.

A ____________ is a sequence of three mRNA bases that codes for one amino acid.

a)

codon

b)

anti-codon

c)

codon wheel

d)

DNA codon

20.

DNA strand ---> ATC

find the mRNA and then translate it into an amino acid

(a)  

21.

Which mutation does not result in a frameshift mutation?

(a)  

22.

(Write 1-2 sentences) Predict what could occur to a gene if a base is substituted, inserted, or deleted. Consider the impacts of these changes on the reading frame and on the protein that is produced.

4 lines
23.

Circle the nucleotide in which the mutation happened (insertion).

24.

List all possible treatments for Kai, as well as your ideas for his health over his lifetime.

4 lines