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WorksheetsCase Study:
Total questions: 14
Worksheet time: 10mins
What is the disease or infection name?
Listeriosis
Legionellosis or Legionnaire's disease
Legionella pneumophila
What is the name of the pathogen?
Legionella pneumophila
Legionellosis or Legionnaire's disease
Listeriosis
Symptoms of the disease include:
Cough, fever or chills
Shortness of breath
Confusion, headache, muscle/body ache
Fatigue, coma
Nausea or vomiting
True or false: surface coats that inhibit phagocytosis are a virulence factor of legionellosis
(a)
True or false: Factors that initiate a hyperactive innate immune response by creating a cytokine storm, which consequently can lead to dampening of T-cell mediated antiviral functions are a virulence factor of legionellosis.
(a)
True or false: pili that ensure attachment and prevent dislocation by mucociliary clearance are a virulence factor of legionellosis.
(a)
True or false: spike proteins that facilitate host cell invasion and escape from detection are a virulence factor of legionellosis.
(a)
True or false: The immune system mounts a cell-mediated reaction in which macrophages attach to the outer walls of the bacteria for active phagocytosis. The engulfed bacteria proliferate within the macrophages. This is a virulence factor of legionellosis.
(a)
What treatments approved by the FDA for legionellosis?
Azithromycin
Regeneron
Inmazeb
Ebanga
Remdesivir
What type of organism is L. pneumophila?
Bacteria
Protozoa
Virus
Since the pathogen is bacterial, is it gram positive or gram negative?
(a)
What is the morphology of legionella?
(a)
What is the mode of transmission for L. pneumophila?
(a)
Is there a licensed vaccine to prevent L. pneumophila infection?
(a)
