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Chapter 7 RadBio

Total questions: 20

Worksheet time: 11mins

Name
Class
Date
1.

Somatic cells divide through the process of:

a)

Meiosis

b)

Mitosis

c)

Malsma

d)

Mitoes

2.

The dose that would cause temporary sterility for up to 12 months  

a)

2 Gy

b)

0.02 Gy

c)

20 Gy

d)

0.2 Gy

3.

Human beings who receive whole-body doses in excess of 5 Gyt may die within 30 to 60 days because of effects related to an initial depletion of the stem cells of the_______________.

a)

hematopoietic

b)

digestive system

c)

reproductive system

d)

nervous system

4.

Which of the following groups of cells is most radiosensitive?

a)

White Blood Cells

b)

Lymphocytes

c)

Erythrocytes

d)

Nutrophils

5.

Exposure with x-ray or gamma-ray dose of 1000 Gray in a period of a few seconds:

a)

Reproductive Death

b)

Apoptosis Cell Death

c)

Instant Death

d)

Chromosome Break

6.

The presence of free radicals in tissue does not affect the amount of biologic damage that results from radiation

a)

True

b)

False

7.

The radiosensitivity of ova

a)

remains constant throughout the lifetime of the germ cell

b)

varies slightly throughout the lifetime of the germ cell

c)

is insignificant because the germ cell is not radiosensitive

d)

varies considerably throughout the lifetime of the germ cell

8.

The term apoptosis is synonymous with

a)

Programmed cell death

b)

Mitotic delay

c)

Interference with function

d)

Instant Cell Death

9.

What governs the radiation dose required to cause apoptosis?

a)

the phase of the cell cycle the individual cell is undergoing

b)

changes in the cell protein content

c)

the radiosensitivity of the individual cell

d)

the number of cells irradiated

10.

When LET increases, the chance of producing a significant biologic response in the radiosensitive DNA macromolecule

a)

increases

b)

decreases

c)

remains constant, not increasing or decreasing

11.

When are human ovaries most radiosensitive?

a)

from 20 to 30 years of age

b)

during the fetal stages of life and during early childhood

c)

after puberty and the onset of menstruation

12.

When free radicals previously produced by the interaction of radiation with water molecules act on a molecule such as DNA, the damaging action of ionizing radiation is indirect in the sense that the radiation is not the immediate cause of injury to the macromolecule. What is the immediate cause of this damage?

a)

Enzymes released from biologic macromolecules

b)

Excitation of the atoms of the biologic macromolecules

c)

The recombining of a positively charged water molecule with an electron

d)

The free radicals produced by the interaction of radiation with water molecules

13.

Which of the following curves illustrates the radiation sensitivity of a particular type of cell?

a)

Cell specialization curve

b)

Cell extrapolation curve

c)

Dose–response curve

d)

Cell survival curve

14.

Which of the following describes the ratio of the radiation dose required to cause a particular biological response of cells or organisms in an oxygen-deprived environment to the radiation dose required to cause an identical response under normal oxygenated conditions?

a)

OER

b)

RBE

c)

KVP

d)

LET

15.

Which of the following is useful for explaining cell death and nonfatal cell abnormalities caused by exposure to radiation?

a)

covalent cross-linking

b)

Bergonie-Tribondeau law

c)

programmed cell death

d)

Target theory

16.

Which of the following statements is true concerning patients who receive radiation exposure from a routine radiographic procedure such as a chest x-ray?

a)

Patients are expected to sustain some damage to either the blood or the blood-forming organs as a consequence of the examination

b)

Patients are expected to sustain appreciable damage to either the blood or the blood-forming organs as a consequence of the examination

c)

Patients are not expected to sustain appreciable damage to either the blood or the blood-forming organs as a consequence of the examination

d)

Patients are expected to sustain total damage to either the blood or the blood-forming organs as a consequence of the examination, resulting in fatality

17.

Which of the following tissues contain cells that do not divide?

1. Epithelial tissue,

2. Muscle tissue,

3. Nervous tissue in an adult

a)

1 and 2 only

b)

1 and 3 only

c)

2 and 3 only

18.

Tissues that are _____ and _____ are more radiosensitive.

a)

mature, specialized

b)

immature, specialized

c)

immature, undifferentiated

d)

mature, undifferentiated

19.

The law of Bergonie and Tribondeau states that the radiosensitivity of cells is _____ proportional to the reproductive activity and ______ to their degree of differentiation.

a)

directly, indirectly

b)

directly, directly

c)

indirectly, indirectly

d)

indirectly, directly

20.

The principal radiation interaction within the human body occurs with _____.

a)

DNA

b)

RNA

c)

H2O