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Worksheets

2.2.2

Total questions: 25

Worksheet time: 14mins

Name
Class
Date
1.

What is the is the most common START codon that codes for the amino acid methionine (Met) in eukaryotes?

a)

AGU

b)

AUU

c)

AUG

d)

ACG

2.

RNA polymerase

a)

makes proteins from mRNA.

b)

makes tRNA from mRNA.

c)

makes an mRNA from a sequence of DNA.

d)

makes DNA from mRNA.

3.

Translation starts

a)

at any sequence.

b)

at AUG.

c)

in the nucleus.

d)

at the very first 3-base sequence.

4.

The anticodon is found on ________________ and is complimentary to ________________.

a)

tRNA; 3 bases on the mRNA

b)

mRNA; 3 bases on the tRNA

c)

mRNA; 3 bases on the mRNA

d)

tRNA; 3 bases on the DNA

5.

Amino acids are put together by the _______________ based on the 3-bases sequence found on the _______________ called the _____________.

a)

tRNA; tRNA; anticodon

b)

ribosomes; tRNA; anticodon

c)

RNA polymerase; mRNA; codon

d)

ribosomes; mRNA; codon

6.

Another term for the process of DNA--> mRNA --> protein is

a)

replication

b)

protein synthesis

c)

gene expression

d)

translation

7.

When transcribing DNA into mRNA,

a)

only the template strand is read by DNA polymerase.

b)

only the amino acid sequence is read by tRNA.

c)

only the non-coding strand is read by RNA polymerase.

d)

only the template strand is read by RNA polymerase.

8.

Transcription occurs in the _________________; translation occurs in the ___________________.

a)

cytoplasm; nucleus

b)

nucleus; nucleus

c)

nucleus; cytoplasm

d)

cytoplasm; cytoplasm

9.

The DNA sequence GGA will be represented by what amino acid?

a)

leu (leucine).

b)

gly (glycine).

c)

glu (glutamic acid).

d)

pro (proline).

10.

In the DNA sequence TACAGTCAA, what would happen if the G was changed to a C so the new sequence would be TACACTCAA

*two correct responses

a)

The mRNA sequence would be AUGUGAGUU.

b)

The mRNA sequence would not be affected.

c)

The amino acid sequence would prematurely stop, making it shorter than normal.

d)

The amino acid sequence would not be affected.

11.

If a DNA sequence went from GGT to GGG, what would happen?

a)

The amino acid would go from Pro to Gly.

b)

The amino acid would go from Gly to Pro.

c)

The amino acid would not change (it would stay Pro).

d)

The amino acid would go from Pro to Arg.

12.

What would most likely happen if RNA polymerase is not working properly?

a)

Either mistakes will be made during transcription, or transcription would not occur.

b)

Transcription nor translation would not be affected.

c)

DNA would be destroyed.

d)

Either mistakes will be made during translation, or translation would not occur.

13.

If the DNA sequence TACCCAATT were mutated so that an extra nucleotide was inserted in between the last two T's so that the new sequence is now TACCCAATGT, what would most likely happen?

a)

Translation would stop prematurely (sooner than normal) because a stop codon occurs earlier than it should; thus, the polypeptide would be shorter than normal.

b)

Translation would not start because the start codon is changed.

c)

Nothing would happen (no changes would occur).

d)

The stop codon is changed so instead of stopping, translation would continue making the polypeptide longer than it should be.

14.

The gene for neurofibromin

a)

is found on chromosome 17.

b)

codes for a protein that drives cellular reactions.

c)

is important in controlling mitosis.

d)

codes for a protein that builds structures.

15.

RNA

a)

contains T's.

b)

contains U's.

c)

is double-stranded like DNA.

d)

is made from ribose sugar instead of deoxyribose sugar.

16.

NF1 disease is caused by a(n) ___________ mutation while sickle cell anemia is caused by a(n) ___________ mutation.

a)

insertion; substitution

b)

substitution; deletion

c)

insertion; deletion

d)

insertion; insertion

17.

Sickle cell anemia is caused by a mutation that causes a change in the structure of the protein

a)

collagen

b)

neurofibromin

c)

insulin

d)

hemoglobin

18.

Hormonal proteins that help maintain homeostasis in the body and sensory proteins help the body interpret the environment are types of proteins that

a)

are involved in movement.

b)

coordinate cellular activities.

c)

transport materials.

d)

drive cellular reactions.

19.

Which of the following proteins is an example of proteins that build structures in the body?

a)

proteins that control mitosis

b)

proteins that fight viruses

c)

keratin

d)

myosin

20.

What type of mutation is shown here?

a)

a substitution mutation

b)

a deletion mutation

c)

an insertion

d)

a frameshift mutation

21.

Which of the following shows a nonsense substitution mutation?

a)
b)
c)
d)
22.

The following shows a(n)

a)

substitution mutation

b)

insertion mutation.

c)

frameshift mutation.

d)

deletion mutation.

23.

The following figure shows

a)

DNA being mutated.

b)

DNA being destroyed.

c)

DNA being sequenced.

d)

DNA translating into a protein.

24.

Which of the following is the responsibility or are the responsibilities of a geneticist?

a)

studies genes and gene inheritance

b)

compares gene sequences from a patient and compares them to gene sequences of wild-type (normal) genes

c)

draw conclusions related to a patient's genetic health

d)

give treatments to patients for genetic diseases

25.

Which of the following is (are) correct?

a)

NF1 disease --> insertion mutation in the neurofibromin gene

b)

Tay-Sachs disease --> insertion mutation in the HEXA gene

c)

sickle cell anemia --> substitution mutation in the hemoglobin gene

d)

diabetes type 2 --> deletion mutation in the insulin gene