WorksheetsClin Med GI 2 - Mudd's lectures
Total questions: 71
Worksheet time: 37mins
External Sphincter
skeletal and voluntary
smooth and involuntary
Internal anal spincter
skeletal and voluntary
smooth and involuntary
mucous membrane like the rest of the gastrointestinal tract
above dentate line
below dentate line
epithelium is considered cutaneous
above dentate line
below dentate line
_______ the dentate line in sensitive. ______ the line is NOT ***
below ; above
above ; below
Arterial Supply: Above Dentate Line
Superior Rectal artery (from Inferior Mesenteric artery)
Inferior Rectal artery (from Internal Pudendal artery)
Arterial Supply: Below Dentate Line
Superior Rectal artery (from Inferior Mesenteric artery)
Inferior Rectal artery (from Internal Pudendal artery)
Venous Drainage: Above Dentate Line
Superior Rectal vein to Inferior Mesenteric vein (portal system)
Inferior and Middle Rectal veins to Internal Illiac veins
Venous Drainage: Below Dentate Line
Superior Rectal vein to Inferior Mesenteric vein (portal system)
Inferior and Middle Rectal veins to Internal Illiac veins
secrete mucous
Anal Glands
Anal Crypts
empty gland secretions into canal
Anal Glands
Anal Crypts
hemorrhoid most common complaint ***
Bleeding with defecation
Swelling
Itching
Mucoid discharge
Internal Hemorrhoid
Above dentate line
generally painless
Below dentate line
generally painful
External Hemorrhoid
Above dentate line
generally painless
Below dentate line
generally painful
Thrombosed External Hemorrhoid management
bedside excision
elective surgical repair
non-emergent hemorrhoidectomy
emergent hemorrhoidectomy
Second or Third-Degree Internal Hemorrhoid
bedside excision
elective surgical repair
non-emergent hemorrhoidectomy
emergent hemorrhoidectomy
Fourth Degree Hemorrhoid
bedside excision
elective surgical repair
non-emergent hemorrhoidectomy
emergent hemorrhoidectomy
Thrombosed or Gangerous fourth degree hemorrhoid
bedside excision
elective surgical repair
non-emergent hemorrhoidectomy
emergent hemorrhoidectomy
Internal Hemorrhoids
Receive blood supply from inferior hemorrhoid plexus
Covered with modified squamous epithelium (anoderm)
Receive blood supply from superior hemorrhoid plexus
Covered with mucosal surface of transitional epithelium
External Hemorrhoids
Receive blood supply from inferior hemorrhoid plexus
Covered with modified squamous epithelium (anoderm)
Receive blood supply from superior hemorrhoid plexus
Covered with mucosal surface of transitional epithelium
Protrudes into the anal canal but does not prolapse, painless w sense of fullness [internal hemorrhoids]
Grade I
Grade II
Grade III
Grade IV
Prolapses but reduces spontaneously, occurs during defecation [internal hemorrhoids]
Grade I
Grade II
Grade III
Grade IV
Prolapses and requires manual reduction, occurs spontaneously and requires manual reduction [internal hemorrhoids]
Grade I
Grade II
Grade III
Grade IV
Irreducible prolapse [internal hemorrhoids]
Grade I
Grade II
Grade III
Grade IV
Most common cause of intensely painful rectal bleeding of sudden onset ***
Anal Fissure
Abscesses and Fistulas
Pilonidal Cyst
Fecal Impaction
Superficial tear in anoderm
Anal Fissure
Abscesses and Fistulas
Pilonidal Cyst
Fecal Impaction
Anal fissures typically occur at __________, but ________ fissures are more common in women
posterior midline (6 o’clock); anterior midline
anterior midline; posterior midline (6 o’clock)
Anal fissures may become chronic and develop fissure triad ***
deep ulcer
sentinel pile
enlarge papillae
fluctuance
localized tenderness
Connection between two epithelium lined surfaces
Perirectal/Perianal Absesses
Ischiorectal Absesses
Intersphincteric Absesses
Supralevator Absesses
Fistula in ano
Fistula in ano develops in 50-67% percent of patients with
Perirectal/Perianal Absesses
Ischiorectal Absesses
Intersphincteric Absesses
Supralevator Absesses
Produce painful swelling at the anal verge, most common
Perirectal/Perianal Absesses
Ischiorectal Absesses
Intersphincteric Absesses
Supralevator Absesses
Deep to external sphincter and inferior to levator ani
•May appear to be a mass in the rectum, may be confused with internal hemorrhoid
Perirectal/Perianal Absesses
Ischiorectal Absesses
Intersphincteric Absesses
Supralevator Absesses
Outside of sphincter muscles
Perirectal/Perianal Absesses
Ischiorectal Absesses
Intersphincteric Absesses
Supralevator Absesses
Perianal and buttock pain
•23% are obese or suffer DM
•Concurrent disorders such as Crohn’s, PID, diverticulitis
Perirectal/Perianal Absesses
Ischiorectal Absesses
Intersphincteric Absesses
Supralevator Absesses
Emergent surgical treatment is indicated
Perirectal/Perianal Absesses
Ischiorectal Absesses
Intersphincteric Absesses
Supralevator Absesses
Arise in the midline of the sacrococcygeal area in the natal cleft
•Theory that bacteria enter sterile hair follicle and produce inflammation and edema
•Contents result in hair follicle rupture and abscess formation
Anal Fissure
Abscesses and Fistulas
Pilonidal Cyst
Fecal Impaction
Solid immobile bulk of human feces that can develop in the rectum
•Often a complication of chronic constipation and chronic laxative use
•Most common in elderly
Anal Fissure
Abscesses and Fistulas
Pilonidal Cyst
Fecal Impaction
are out pockets of the colonic mucosa and submucosa through weaknesses of muscle layers in the colon wall
Diverticula
Diverticulosis
Diverticulitis
the condition of having diverticula in the colon that are not inflamed.
Diverticula
Diverticulosis
Diverticulitis
when the diverticula become inflamed
Diverticula
Diverticulosis
Diverticulitis
involves the entire GI tract
Crohn's Disease
Ulcerative Colitis
involves just the large bowel
Crohn's Disease
Ulcerative Colitis
Surgery can be curative ***
Crohn's Disease
Ulcerative Colitis
sx: RLQ pain, diarrhea, fatigue. Gradual onset.
Crohn's Disease
Ulcerative Colitis
sx: abdominal pain, hematochezia. Sudden onset.
Crohn's Disease
Ulcerative Colitis
Most common extraintenstinal manifestation of Crohn's disease
Musculoskeletal pain
Skin disorders
Venous and arterial thromboembolism
Uveitis
Ankylosing spondylitis
Most common extraintenstinal manifestation of Ulcerative Colitis
Musculoskeletal pain
Skin disorders
Venous and arterial thromboembolism
Uveitis
Ankylosing spondylitis
more comorbidity w UC than crohns
Musculoskeletal pain
Skin disorders
Venous and arterial thromboembolism
Uveitis
Ankylosing spondylitis
Bloody diarrhea is usually the primary symptom.
Crohn's Disease
Ulcerative Colitis
Toxic Megacolon
Irritable Bowel Syndrome
is characterized by colonic diameter ≥6 cm or cecal diameter >9 cm and the presence of systemic toxicity
Crohn's Disease
Ulcerative Colitis
Toxic Megacolon
Irritable Bowel Syndrome
Patients may have other somatic or psychosocial complaints (fatigue, myalgia, anxiety, depression, dyspepsia)
Crohn's Disease
Ulcerative Colitis
Toxic Megacolon
Irritable Bowel Syndrome
ACG Grading used for classification
Crohn's Disease
Ulcerative Colitis
Toxic Megacolon
Irritable Bowel Syndrome
+/- bleeding per rectum and fewer than 4 BMs per day
Mild UC
Moderate UC
Severe UC
Fulminant UC
Bleeding per rectum with more than 4 BMs per day
Mild UC
Moderate UC
Severe UC
Fulminant UC
Bleeding per rectum, more than 6 BMs per day, and a systemic illness or elevated ESR
Mild UC
Moderate UC
Severe UC
Fulminant UC
greater than 10 BMs per day, continuous bleeding, systemic illness
Mild UC
Moderate UC
Severe UC
Fulminant UC
•Able to tolerate oral alimentation
•Without manifestations of dehydration, toxicity (high fevers, rigors, prostration), abdominal tenderness, painful mass, obstruction, or >10% weight loss
•Ambulatory
Mild-moderate Crohn's
Moderate-severe Crohn's
Severe fulminant disease
Remission
•Fail to respond to treatment for mild-moderate disease, or
•Have more prominent symptoms of fever, significant weight loss, abdominal pain or tenderness, intermittent nausea or vomiting (without obstructive findings), or significant anemia
Mild-moderate Crohn's
Moderate-severe Crohn's
Severe fulminant disease
Remission
•Have persisting symptoms despite the introduction of steroids on an outpatient basis, or
•Present with high fever, persistent vomiting, evidence of intestinal obstruction, rebound tenderness, cachexia, or evidence of an abscess
Mild-moderate Crohn's
Moderate-severe Crohn's
Severe fulminant disease
Remission
•Asymptomatic or without inflammatory sequelae
•Includes those who responded to acute medical intervention or who underwent surgical resection without gross evidence of residual disease
•Without need for glucocorticosteroid therapy ***
Mild-moderate Crohn's
Moderate-severe Crohn's
Severe fulminant disease
Remission
the key to diagnosis of ulcerative colitis ***
colonoscopy
mucosal biopsy
sigmoidoscopy/colonoscopy
CT with contrast
gold standard dx for celiac disease ***
colonoscopy
mucosal biopsy
sigmoidoscopy/colonoscopy
CT with contrast
_______ can be an early manifestation of Crohn's Disease
Aphthous ulcers
Fatigue
Diarrhea
LLQ pain
should be considered in infants and children w persistent sx despite dietary lactose restriction
Celiac Disease (gluten intolerance)
Lactose intolerance
Cow's milk allergy (CMA)
Autoimmune disease that effects the small intestine
Celiac Disease (gluten intolerance)
Lactose intolerance
Cow's milk allergy (CMA)
characterized by an intestinal brush border lactase enzyme activity that is lower than that of normal infants.
Lactase deficiency
Lactose malabsorption
Lactose intolerance
characterized by a failure of the small bowel to absorb a sizable fraction of ingested lactose.
Lactase deficiency
Lactose malabsorption
Lactose intolerance
clinical syndrome in which lactose ingestion causes symptoms (eg, abdominal pain, bloating, flatulence, diarrhea) due to lactose malabsorption
Lactase deficiency
Lactose malabsorption
Lactose intolerance
_____ are the acute manifestation of infection, ______ are the chronic sequalae of these
abscesses; fistulas
fistulas; abscesses
Goodsall's Rule: If the external opening of a fistula lies _____ to a line drawn from 9 o’clock to 3 o’clock then it tracks around the anus laterally and opens into the midline posteriorly
posterior
anterior
Goodsall's Rule: If the external opening of a fistula lies _____ to a line drawn from 9 o’clock to 3 o’clock then it opens directly into the anal canal
posterior
anterior
