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Mutations

Total questions: 12

Worksheet time: 12mins

Name
Class
Date
1.

What type of gene mutation has occurred here? 

Normal: AGA-TTC-ATA-GCG

Mutant: AGA-TTC-AAT-AGC-G

a)
deletion frameshift
b)
insertion frameshift
c)

point

d)
nonsense
2.

One nucleotide base is changed so only one amino acid is affected.

a)

Substitution Mutation

b)

Point Mutation

c)

Frameshift Mutation

d)

Inverse Mutation

3.

A frameshift mutation where a nucleotide base

is removed from the DNA sequence.

a)

Deletion Mutation

b)

Substitution Mutation

c)

Translocation

d)

Silent Mutation

4.
Are all mutations bad?
a)
Yes
b)
No
5.

A mutation is defined as:

a)

A change in the cell's structure

b)

Anything that changes in an embryo

c)

Any change in the physical features of a human

d)

A change in the DNA sequence

6.

Part of a chromosome is repeated

a)

Gene Mutation

b)

Translocation Mutation

c)

Nondisjunction Mutation

d)

Duplication Mutation

7.

Part of one chromosome is transported and attached

to a non-homologous chromosome

a)

Inversion Mutation

b)

Translocation Mutation

c)

Duplication Mutation

d)

Point Mutation

8.

Failure of homologous chromosomes

to separate during meiosis.

Results in gametes with either one extra or one missing chromosome.

a)

Translocation

b)

Nondisjunction

c)

Replication

d)

Transcription

9.

Condition caused by nondisjunction at pair 21 during meiosis.

Individuals have an extra chromosome

at pair 21, or a total of 47 chromosomes.

Also called Trisomy 21.

a)

Cystic Fibrosis

b)

Translocation

c)

Hemophilia

d)

Down Syndrome

10.

__________ is a hereditary disease that affects the lungs and digestive system. The body produces thick and sticky mucus that causes persistent lung infections.

a)

hemophilia

b)

achondroplasia

c)

cystic fibrosis

d)

Huntington's disease

11.

What is Hemophilia?

a)

a medical condition in which the ability of the blood to clot is severely reduced, causing the person to bleed severely from slight injury.

b)

a genetic disorder where there is a 23rd chromosome

c)

a disease where the dystrophin protein is misformed, causing progressive muscle degeneration.

d)

A genetic disorder where there are three copies of chromosome 21

12.

What can cause mutations?

a)

all of these

b)

Mistakes during DNA replication or protein synthesis

c)

Mistakes during mitosis or meiosis

d)

Viruses