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histopathology

Total questions: 58

Worksheet time: 29mins

Name
Class
Date
1.

A 52-year-old male presents with symptoms of gastric pain after eat- ing. During workup, a 3-cm mass is found in the wall of the stomach. This mass is resected and histologic examination reveals a tumor composed of cells having elongated, spindle-shaped nuclei. The tumor does not connect to the overlying epithelium and is found only in the wall of the stomach. This tumor most likely originated from

a)

Adipocytes

b)

Endothelial cells

c)

Glandular epithelial cells

d)

Smooth muscle cells

2.

The first and most critical step in histotechnology?

a)

Fixation

b)

Clearing

c)

Infiltration

d)

Embedding

3.

The primary aim of fixation:

a)

Preserve the morphologic and chemical integrity of the cell

b)

Act as mordant or accentuators

c)

Harden and protect the tissue from trauma of further handling

d)

Inhibit bacterial decomposition

4.

The secondary goal of fixation:

a)

Preserve the morphologic and chemical integrity of the cell

b)

Act as mordant or accentuators

c)

Harden and protect the tissue from trauma of further handling

d)

Inhibit bacterial decomposition

5.

Most ideal and most reliable method of determining extent of decalcification:

a)

Physical test

b)

Chemical test

c)

X-ray or radiological test

d)

All are correct

6.

Excessive exposure to this clearing agent may be extremely toxic to man and may become carcinogenic or it may damage the bone marrow resulting to APLASTIC ANEMIA:

a)

Xylene

b)

Toluene

c)

Benzene

d)

Chloroform

7.

A special form of cell death produced by the tubercle bacillus:

a)

Liquefaction necrosis

b)

Coagulation necrosis

c)

Fat necrosis

d)

Caseous necrosis

8.

It is especially recommended for cutting extremely hard and rough tissue blocks.

a)

Rocking

b)

Rotary

c)

Sliding

d)

Freezing

9.

Ripening of hematoxylin is a process of:

a)

Hydrolysis

b)

Oxidation

c)

Mordanting

d)

Reduction

10.

Harris hematoxylin is used on tissue sections to stain:

a)

Fats

b)

Glycogen

c)

Nuclei

d)

Cytoplasm

11.

The Von Kossa’s stain is used to demonstrate:

a)

Calcium

b)

Amyloid

c)

Glycogen

d)

Fats

12.

Oldest stain:

a)

Orcein

b)

Iodine

c)

Eosin

d)

Hematoxylin

13.

Probably the best vital:

a)

Nile blue

b)

Neutral red

c)

Janus green

d)

Toluidine blue

14.

Vital dye especially recommended for mitochondria:

a)

Nile blue

b)

Neutral red

c)

Janus green

d)

Toluidine blue

15.

The connective tissue cells actively involved in wound healing are:

a)

Plasma cells

b)

Macrophages

c)

Mast cells

d)

Fibroblasts

16.

Acridine orange demonstrates

a)

Cell wall

b)

Mitochondria

c)

Nucleic acid

d)

Flagella

17.

Project coaches/leaders:

a)

White belts

b)

Green belts

c)

Yellow belts

d)

Black belts

18.

Project team members:

a)

White belts

b)

Green belts

c)

Blue belts

d)

Black belts

19.

Green belts contribute _____ of their time to improvement projects while delivering their normal job functions.

a)

20%

b)

50%

c)

70%

d)

100%

20.

Black belts dedicate _____ of their time to quality improvement projects, proactively addressing process and quality problems.

a)

20%

b)

50%

c)

70%

d)

100%

21.

Stains the nucleus:

a)

Acidified eosin

b)

Non-acidified eosin

c)

Acidified hematoxylin

d)

Non-acidified hematoxylin

22.

First step in automated tissue processor:

a)

Cold formalin

b)

Hot formalin

c)

Cold ethanol

d)

Hot ethanol

23.

At low pH, formalin produces a dark pigment which obscure cellular detail. Thus, it is necessary to buffer formalin at pH____ to prevent this occurence.

a)

pH 3

b)

pH 5

c)

pH 7

d)

pH 8

24.

In the Feulgen’s reaction, DNA is stained:

a)

Green

b)

Blue

c)

Reddish-purple/violet

d)

Black

25.

The phosphotungstic acid hematoxylin (PTAH) is useful for demonstrating:

a)

Edema fluid

b)

Muscle striations

c)

Ground substance

d)

Reticulin network

26.

In the ripening of hematoxylin, alkaline (basic) solutions will affect for a _______ oxidizing process

a)

Slower oxidizing process

b)

More rapid oxidizing process

c)

Few hours

d)

None of these

27.

Which of the following ISO standard applies to the clinical laboratory?

a)

ISO 9000

b)

ISO 7000

c)

ISO 15189

d)

ISO 15436

28.

Molecular death:

a)

Flat ECG

b)

Flat EEG

c)

Absent breath sounds

d)

Rigor mortis

29.

Thyroid follicles are lined by this type of epithelium:

a)

Simple squamous epithelium

b)

Simple cuboidal epithelium

c)

Simple columnar epithelium

d)

Transitional epithelium

30.

Due to chronic trauma induced by ill-fitting dentures:

a)

Hypertrophy

b)

Hyperplasia

c)

Dysplasia

d)

Metaplasia

31.

It occurs in the bronchi of cigarette smokers as cellular adaptation to smoke:

a)

Hypertrophy

b)

Hyperplasia

c)

Dysplasia

d)

Metaplasia

32.

RBC inclusion:

Positive Wright's stain

Positive supravital stain

Positive Feulgen reaction

a)

Basophilic stippling

b)

Heinz bodies

c)

Howell-Jolly bodies

d)

Pappenheimer bodies

33.

Tissue is soft when block is trimmed:

a)

Incomplete fixation

b)

Incomplete dehydration

c)

Incomplete clearing

d)

Incomplete impregnation

34.

Tissue is opaque, section cutting is difficult due to the presence of alcohol.

a)

Incomplete fixation

b)

.Incomplete dehydration

c)

Insufficient clearing

d)

Incomplete impregnation

35.

Whenever the drug testing laboratory result is challenged, _______ shall make the final decision.

a)

Crime laboratory of PNP

b)

Crime laboratory of NBI

c)

East Avenue Medical Center

d)

San Lazaro Hospital

36.

Which of the following conducts Proficiency Workshops in HIV and Hepatitis Testing for all medical technologists?

a)

LCP

b)

NKTI

c)

RITM

d)

SACCL-SLH

37.

RESPECT the decisions (self-determination) of individuals who have decision-making capacity.

a)

Autonomy

b)

Beneficence

c)

Non-maleficence

d)

Justice

38.

An Act Regulating the Collection, Processing and Sale of Human Blood, and the Establishment and Operation of Blood Banks and Blood Processing Laboratories

a)

A. RA 5527

b)

B. RA 1517

c)

C. RA 7719

d)

D. RA 8504

39.

AN ACT PROMOTING VOLUNTARY BLOOD DONATION, PROVIDING FOR AN ADEQUATE SUPPLY OF SAFE BLOOD, REGULATING BLOOD BANKS

a)

A. RA 5527

b)

B. RA 1517

c)

C. RA 7719

d)

D. RA 8504

40.

A blood service facility duly authorized by the DOH – Center for Health Development (CHD), whose main function is to collect blood from volunteer non-renumerated blood donors:

a)

A. Blood Bank (BB)

b)

B. Blood center (BC)

c)

C. Blood collection unit (BCU)

d)

D. Blood station (BS)

41.

A blood service facility duly authorized by the DOH – CHD, whose main function is the storage, issuance, transport and distribution of whole blood and packed red cells:

a)

A. Blood Bank (BB)

b)

B. Blood center (BC)

c)

C. Blood collection unit (BCU)

d)

D. Blood station (BS)

42.

A non-hospital-based blood service facility, licensed by DOH Bureau of Health Facilities and Services (BHFS), whose main function is to process blood units into blood components and testing these units for five (5) infectious disease markers:

a)

A. Blood Bank (BB)

b)

B. Blood center (BC)

c)

C. Blood collection unit (BCU)

d)

D. Blood station (BS)

43.

SURVEILLANCE PROCEDURES COVERING WHOLE TRANSFUSION CHAIN:

a)

A. Blood cold chain

b)

B. Health vigilance

c)

C. Hemovigilance

d)

D. Pharmacovigilance

44.

The Professional Regulation Commission, otherwise known as the PRC, is a ____-man commission attached to office of the President for general direction and coordination.

a)

A. Two-man

b)

B. Three-man

c)

C. Four-man

d)

D. Five-man

45.

Licensure exam not under PRC:

a)

A. Geologists

b)

B. Librarians

c)

C. Lawyers

d)

D. Master plumbers

46.

Introduced medical technology practice in the Philippines after World War II:

a)

A. Dr. Pio de Roda

b)

B. Dr. Mariano Icasiano

c)

C. Dr. Prudencia Sta. Ana

d)

D. 26th Medical Laboratory of the 6th US Army

47.

A class ABC fire extinguisher contains:

a)

A. Sand

b)

B. Water

c)

C. Dry chemicals

d)

D. Acid

48.

Waste container for empty aerosol cans:

D. Red

a)

A. Yellow

b)

B. Yellow with black band

c)

C. Black

d)

D. Red

49.

Carbon dioxide for extinguishers are suitable for use with the following hazards:

a)

A. Cloth and electrical

b)

B. Wood and flammable gas

c)

C. Flammable liquids and electrical

d)

D. Paper and natural gas

50.

Exotic agents considered high risk and cause life-threatening disease:

a)

A. BSL-1 agents

b)

B. BSL-2 agents

c)

C. BSL-3 agents

d)

D. BSL-4 agents

51.

Due to chronic trauma induced by ill-fitting dentures:

a)

A. Hypertrophy

b)

B. Hyperplasia

c)

C. Dysplasia

d)

D. Metaplasia

52.

A 53-year-old woman with no prior illnesses has a routine checkup by her physician. On examination she has a blood pressure of 150/95 mm Hg. If her hypertension remains untreated for years, which of the following cellular alterations would most likely be seen in her myocardium?

a)

A. Dysplasia

b)

B. Fatty change

c)

C. Hyperplasia

d)

D. Hypertrophy

53.

A universal fixative used for routine purposes:

a)

A. Zenker fluid

b)

B. Zamboni PAF

c)

C. 10% neutral buffered formalin

d)

D. Carnoy's fluid

54.

Ripening of hematoxylin is a process of:

a)

A. Hydrolysis

b)

B. Oxidation

c)

C. Mordanting

d)

D. Reduction

55.

Preparation of 1 liter 10% formalin from 40% formaldehyde:

A. 10 mL 40% formaldehyde to 990 mL water

B. 100 mL 40% formaldehyde to 900 mL water

C. 1 mL 40% formaldehyde to 999 mL water

D. 400 mL 40% formaldehyde to 600 mL water

a)

A. 10 mL 40% formaldehyde to 990 mL water

b)

B. 100 mL 40% formaldehyde to 900 mL water

c)

C. 1 mL 40% formaldehyde to 999 mL water

d)

D. 400 mL 40% formaldehyde to 600 mL water

56.

Oldest stain:

a)

A. Orcein

b)

B. Iodine

c)

C. Eosin

d)

D. Hematoxylin

57.

The four essential functions of a manager are:

a)

A. Staffing, decision making, cost analysis, evaluating

b)

B. Directing, leading, forecasting, implementing

c)

C. Planning, organizing, directing, controlling

d)

D. Innovating, designing, coordinating, problem-solving

58.

The material safety data sheets (MSDSs) for hazardous chemicals address which of the following conditions?

a)

A. Physical characteristics of the chemical

b)

B. Safe handling and storage of the chemical

c)

C. Specific health hazards associated with the chemical

d)

D. All of these options