WorksheetsAnthelmintic Drugs
Total questions: 26
Worksheet time: 13mins
A 32-year-old man is diagnosed with whipworm disease after he spent the summer working outside with· out shoes. Which would be the best treatment option?
Pyrantel pamoate
Mebendazole
Thiabendazole
Diethylcarbamazine
Which combination would be appropriate to use for preventative chemotherapy in countries with endemic filariasis and endemic onchocerciasis?
Pyrantel pamoate and mebendazole
lvermectin and diethylcarbamazine
Albendazole and diethylcarbamazine
lvermectin and albendazole
Which statement best describes the mechanism of action of pyrantel pamoate
Acts as a depolarizing neuromuscular blocking agent leading to paralysis of the worm
Binds to p-tubulin and inhibits the assembly of the microtubules polymerization in the parasite
Inhibits the mitochondrial phosphorylation of adenosine diphosphate (ADP) in the parasite
Inhibits glucose uptake leading to parasite death
Which is the best treatment option for treatment of cutaneous larva migrans? A. Pyrantel pamoate B. Diethylcarbamazine C. lvermectin D. Niclosamide
Pyrantel pamoate
Diethylcarbamazine
lvermectin
Niclosamide
Which medication used to treat river blindness targets chloride channels and can cause a Mazzoni reaction? A. lvermectin B. Praziquantel C. Pyrantel pamoate D. Albendazole
lvermectin
Praziquantel
Pyrantel pamoate
Albendazole
A 48-year-old immigrant from Mexico presents with seizures and other neurologic symptoms. Eggs of Taenia solium are found in a stool specimen. A magnetic resonance image of the brain shows many cysts, some of which are calcified. Which drug would be of benefit to this individual?
lvermectin
Pyrantel pamoate
Albendazole
Diethylcarbamazine
Which drug works by increasing the permeability of the cell membrane to calcium
Albendazole
lvermectin
Niclosamide
Praziquantel
When used for treatment of taeniasis, a laxative is usually administered prior to oral administration of which drug?
Mebendazole
Diethylcarbamazine
Niclosamide
Pyrantel pamoate
A 37-year-old man presents with diarrhea and gastrointestinal bleeding. Eggs of Schistosoma mansoni are found upon examination of a stool specimen. The patient has a history of seizures and is currently on phenytoin. Metabolism of which medication will be increased due to his current drug regimen? A lvermectin B. Praziquantel C. Thiabendazole D. Niclosamide
lvermectin
Praziquantel
Thiabendazole
Niclosamide
When used for longer treatment, such as hydatid disease, which medication is associated with risks of hepatotoxicity and agranulocytosis?
Albendazole
Diethylcarbamazine
Niclosamide
lvermectin
Tick the drug, blocking acetylcholine transmission at the myoneural junction of helminthes
Levamisole
Mebendazole
Piperazine
Niclosamide
Tick niclosamide mechanism of action: a) Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthesb) Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes c) Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake d) Inhibiting oxidative phosphorylation in some species of helminthes
Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes
Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes
Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake
Inhibiting oxidative phosphorylation in some species of helminthes
Tick praziquantel mechanism of action
Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes
Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake
Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death ofhelminthes
Inhibiting oxidative phosphorylation in some species of helminthes
Tick piperazine mechanism of action
Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake
Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes
Inhibiting oxidative phosphorylation in some species of helminthes
Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes
Tick the drug, a salicylamide derivative:
Praziquantel
Piperazine
Mebendazole
Niclosamide
Tick mebendazole mechanism of action: a) Inhibiting oxidative phosphorylation in some species of helminthes b) Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthesc) Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake d) Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes
Inhibiting oxidative phosphorylation in some species of helminthes
Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes
Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake
Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes
Tick the drug, inhibiting oxidative phosphorylation in some species of helminthes:
Niclosamide
Piperazine
Praziquantel
Mebendazole
Tick the drug for neurocysticercosis treatment: a) Praziquantel b) Pyrantel c) Piperazine d) Bithionol
A
B
C
D
Tick the drug for nematodosis (roundworm invasion) treatment: a) Niclosamide b) Praziquantel c) Bithionol d) Pyrantel
A
B
C
D
Tick the drug for cestodosis (tapeworm invasion) treatmen
Piperazine
Praziquantel
Pyrantel
Ivermectin
Tick the drug for trematodosis (fluke invasion) treatment:
Bithionol
Ivermectin
Pyrantel
Metronidazole
Tick the drug, a benzimidazole derivative: a) Praziquantel b) Mebendazole c) Suramin d) Pyrantel
Praziquantel
Mebendazole
Suramin
Pyrantel
Tick the broad spectrum drug for cestodosis, trematodosis and cycticercosis treatment
Piperazine
Ivermectine
Praziquantel
Pyrantel
Tick the drug for ascaridosis and enterobiosis treatment:
Bithionol
Pyrantel
Praziquantel
Suramin
Tick the drug for strongiloidosis treatment:
Niclosamide
Praziquantel
Bithionol
Ivermectin
Tick the drug for echinococcosis treatment:
Suramin
Mebendazole or Albendazole
Piperazine
Iodoquinol
