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Adaptive Immune Response

Total questions: 22

Worksheet time: 13mins

Name
Class
Date
1.
What process coats the antigen with antibody to make it more likely to be phagocytosed?
a)
opsonization
b)
blanketing
c)
immunization
d)
framing
2.
Which cells are responsible for producing large quantities of antibodies?
a)
T cells
b)
natural killer cells
c)
plasma cells
d)
macrophages
3.

Which cells kill cancer cells and infected cells by inducing apoptosis

a)
cytotoxic T cells
b)
B cells
c)
mast cells
d)
eosinophils
4.
Which type of immunity has memory?
a)
innate
b)
adaptive/acquired
5.
Which branch of immunity involves B cells?
a)
Cell-mediated
b)
Humoral
6.
A molecule that induces an immune response?
a)
antibody
b)
receptor
c)
antigen
d)
sebum
7.
Where do T cells mature?
a)
bone marrow
b)
thymus
c)
brain
d)
thyroid
8.

The blue molecule in this image is a(n) _______.

a)

Antibody

b)

Antigen

c)

Pathogen

d)

Blood cell

9.

These cells hep to activate or program certain cells in Humoral AND Cell Mediated Response

a)

helper T cell

b)

mast cell

c)

cytotoxic T cell

d)

plasma cells

10.

If a person has already had chicken pox, why do they generally not get sick a second time?

a)

Memory B and T cells activate the immune system before the virus has a chance to make you sick

b)

Natural killer cells recognize the pathogen quicker

c)

Your 1st line of defense does a better job

11.

Which of the following does a cytotoxic T cell have to see in order to kill an infected cell?

a)

Antigen on MHC1

b)

Nothing

c)

Antigen on the body cell's MHC2

d)

Antigen on the cell's surface

12.

How do naive B cells become clonally selected?

a)

They see antigen presented on an APC

b)

They see free antigen specific to their receptor

c)

They receive interleukins from an active Helper T cell

d)

They see specific antigen complementary to their receptor on an APC

13.

What happens after a clonally selected B or T cell is stimulated by interleukin from a Th cell?

a)

It proliferates into memory cells

b)

It clonally expands and differentiates

c)

It becomes a T helper cell

d)

It is able to start producing antibodies

14.

Which is the best definition of agglutination?

a)

Binding to the membrane of pathogens to initiate the membrane attack complex

b)

Preventing a pathogen's cell-binding ability

c)

Binding to toxins to prevent their harmful action

d)

Clumping together pathogens to immobilise them + facilitate phagocytosis

15.

Which of the following molecules do Cytotoxic T cells secrete?

a)

Histamine

b)

Interleukins

c)

Granzymes + perforin

d)

Insulin

16.

antigen presenting cells (a)   and enzymatically digest pathogens before placing antigen on their surface MHC2

17.

Which adaptive immune response is best suited to intracellular pathogens?

a)

Humoral

b)

Cell-mediated

c)

Innate

18.

Naive T cells become clonally selected after being presented antigen on an APC's (a)   molecule. This antigen must be complementary to their T cell receptor

19.

Without these cells neither the humoral nor cell-mediated immune responses would become activated

a)

plasma cells

b)

neutrophils

c)

mast cells

d)

T helper cells

20.

The inner chain of an antibody is known as the

a)

heavy chain

b)

light chain

c)

alpha chain

d)

beta chain

21.

What is the name given to the bond that holds the heavy and light chain together (at two sites)

a)

hydrogen bond

b)

covalent bond

c)

peptide bond

d)

disulphide bridge

22.

What is apoptosis?

a)

Unexpected cell death

b)

Cell death caused by infection

c)

Controlled cell death

d)

Death caused by phagocytosis