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BOC Sem II First Year B Pharmacy

Total questions: 20

Worksheet time: 20mins

Name
Class
Date
1.

Intermediate that is common in glycolysis, glycogenesis and glycogenolysis is

a)

Glucose-1,6-bisphosphate

b)

Glucose-1-phosphate

c)

Glucose-6-phosphate

d)

Fructose-1,6-bisphosphate

2.

Gout is caused due to impaired excretion or overproduction of _______.

a)

Uric acid

b)

Xanthine

c)

Hypoxanthine

d)

Adenine

3.

Amino acid precursor involved in De Novo synthesis of pyrimidine is

a)

Aspartate

b)

Glycine

c)

Serine

d)

Alanine

4.

Which of the following enzyme is involved in salvage pathway of purines?

a)

Adenine phosphoribosyl transferase

b)

Glutamine- PRPP amidotransferase

c)

IMP dehydrogenase

d)

Adenylosuccinate synthetase

5.

Glycolysis occurs in

a)

Cytosol

b)

Mitochondria

c)

Nucleus

d)

Lysosome

6.

Dopamine is synthesized from

a)

tyrosine

b)

tryptophan

c)

threonine

d)

lysine

7.

The conversion of 1,3-bisphosphoglycerate to 3- phosphoglycerate catalysed by enzyme

phosphoglycerate kinase resulting in the synthesis of ATP is a good example of

a)

Oxidative Phosphorylation

b)

Oxidative dephosphorylation

c)

Substrate level Phosphorylation

d)

Photophosphorylation

8.

The common enzyme involved in metabolism of cholesterol and ketone body is

a)

HMG CoA reductase

b)

HMG CoA lyase

c)

HMG CoA synthase

d)

HMG CoA thiolase

9.

Which of the following enzyme catalyzes the first step of glycolysis?

a)

Hexokinase

b)

Pyruvate kinase

c)

Glucokinase

d)

Phosphofructokinase-1

10.

In Krebs (TCA) cycle, when two carbon Acetyl CoA is oxidized to CO2, the total yield of

ATP is

a)

8

b)

12

c)

14

d)

16

11.

Palmitoyl CoA undergoes ____ cycles of oxidation to yield 8 acetyl CoA.

a)

7

b)

12

c)

14

d)

16

12.

First step of the beta -oxidation of fatty acids involves

a)

Deactivation of fatty acids occurring in the cytosol

b)

Activation of fatty acids occurring in the cytosol

c)

E-Oxidation proper in the mitochondrial matrix.

d)

Transport of fatty acids into mitochondria

13.

Glucose-6-phosphate is intermediate that is common in

a)

Glycolysis, and Glycogenesis

b)

Glycolysis and Tri carboxylic Acid

c)

Glycolysis and Electron Transport Chain

d)

Tri carboxylic Acid & Electron Transport Chain

14.

In Electron Transport Chain enzyme require for complex IV is _____

a)

NADH CoQ reductase

b)

ATP Synthetase

c)

Cytochrome oxidase

d)

Succinate reductase

15.

Phospholipids are important cell membrane components since

a)

They have glycerol

b)

Have polar and non-polar portions

c)

Form bilayers in water

d)

Combine covalently with proteins

16.

The gaps between segment of DNA on the lagging stand produced by restriction

enzymes are joined/sealed by:

a)

DNA Topoisomerase

b)

DNA Helicase

c)

DNA Ligase

d)

DNA Phosphorylase

17.

____ is a start codon.

a)

UAG

b)

UAA

c)

AUG

d)

UGA

18.

Strand of DNA from which mRNA is formed by transcription is called ___________.

a)

Template

b)

Anti-template

c)

Coding

d)

Transcript

19.

TATA box and ‘–35’ sequence are involved in___________.

a)

DNA replication

b)

The correct binding of the enzyme RNA polymerase to DNA

c)

Termination step of RNA synthesis

d)

Elongation step of RNA synthesis

20.

Which of the following work is done by the sigma factor in transcription?

a)

Helicase action

b)

Transcription termination

c)

Transcription elongation

d)

Transcription initiation