WorksheetsCADD Assessment I-Practice Session
Total questions: 6
Worksheet time: 3mins
What is the principle behind Computational Drug Design?
The understanding of the process of drug discovery and development from the identification of novel drug targets to the introduction of new drugs into clinical practice.
Involves only modern patterns in compound characterization
Modern techniques for data collection
Technique to assess chemical compounds
What does the statement " from a million to one" stand for?
Reversion to one of a million Drug design concepts
Reversion to one of a million compounds
Reversion to one of a million receptors
Reversion to one of a million fragments
What does PDB stand for?
Protein Data Bank
Python Debugger
Prescription Drugs Branch
Paget Disease Of Bone
Why do we need to prepare ligands before docking?
To generate 3-dimensional geometries and ligand properties like molecular weight etc.
To generate 3D figures.
To add hydrogen atoms,
add missing amino acids and hetero groups
To generate 3-dimensional geometries,
assign proper bond orders, accessible tautomer, and
ionization states generate
Docking can be performed between?
only small molecules and protein
two proteins
antibody and protein
between all kinds of proteins and between all kinds of small molecules and receptor
Which target should we choose from the signalling cascade related to disease?
rate-limiting target
multi-responsive target
a gene
any protein in the cascade
