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WorksheetsEndocrine System
Total questions: 67
Worksheet time: 35mins
A kidney donor suffered damaged to the renal artery during the surgery. Which of the following adrenal arteries could be?
Superior adrenal artery
Middle adrenal artery
Inferior adrenal artery
Inferior phrenic artery
A 46-year-old woman is evaluated for voice changes after thyroid surgery. The patient was diagnosed with papillary thyroid cancer and subsequently underwent thyroidectomy. Immediately after the surgery, she noticed persistent hoarseness and dysphagia. Which nerve was most likely injured during the surgery.
Right vagus nerve
Lymphatic nodes
Jugular vein
Recurrent larygeal nerves
The adrenal glands are ____ glands that produce a variety of hormones.
Exocrine
Endocrine
Exterior
Interior
Where are the adrenal glands found?
Pancrea
Kidneys
Galbladder
Stomach
What does the outer cortex of the adrenal gland produce?
Steroid hormones
Norepinephrine
Dopamine
Mineralocorticoids
What does the inner medulla of the adrenal gland produce
Androgens
Glucocorticoids
Steroid hormones
Catecholamines
Mineralocorticoids (aldosterone) effects:
Regulate sodium
Water reabsorption
Potassium excretion
All are correct
Glucorticoids (cortisol) effects:
Steroid hormones
Glucose metabolism
Water reabsorption
Potassium absorption
Adrenal sex hormones controls:
Growth
Blood flow
Development
Glucose
What is the source for synthesis of all steroid hormones
Glucose
Epinephrine
Dopamine
Cholesterol
Adrenal glands are
Primary Retroperitoneal organs
Intraperiotoneal organs
Secondary Retroperitoneal organs
Subperitoneal organs
Mineralcorticoid synthesis occurs at the zone
Glomerulosa
Fasciculata
Reticularis
Chromaffin cells
The main site of the synthesis of glucocorticoids is at the zone
Reticularis
Fasciculata
Glomerulosa
Chromaffin cells
Arterial blood supply of adrenal glands
Superior suprarenal artery
Internal carotid artery
Inferior suprarenal artery
Middle suprarenal artery
What does the medulla of the adrenal gland produce?
Catecholamines
Epinephrine
Norepinephrine
Steroid hormones
Main site of androgen production
Glomerulosa
Reticularis
Cortex
Medulla
What structure holds the pituitary gland?
Hypothalamus
Sella turcica
Sphenoid bone
Hypohyseal fossa
Pituitary gland is also called
hypophysis
master gland
PTH gland
The anterior lobe carries out the important task of
blood flow
hormone production
glucose regulation
Gastrin production
Acidophils are ____ and look ____ on H&E, while basophils are ____ and look ____ on H&E.
acid loving and look pink; base loving and look blue-purple
base loving and look pink; acid loving look blue-purple
acid loving and look pink; base loving look pink
base loving and look blue-purple; acid loving look blue-purple
Acidophils include two main hormones -producing cells-
Somatrophs and Thyrotroph
Thyrotroph and Gonadotroph
Corticotroph and Mammatroph
Mammatroph and Somatotroph
Somatotroph produces
Growth hormone
Prolactin
Thyroid-stimulating hormone
Follicle-stimulating hormone and luteinizing hormone
Mammotroph produces
Growth hormone
Adrenocroticotropic hormone and a-melanocyte stimulating hormone
Prolactin
Thyroid-stimulating hormone
Gonadotroph produces
Prolactin
Follicle-stimulating hormone and luteinizing hormone
Thyroid-stimulating hormone
Adrenocorticotropic hormone and a-melanocyte stimulating hormone
Corticotroph produces
Adrenocorticotropic hormone and a-melanocyte stimulating hormone
Prolactin
Growth hormone
Follicle-stimulating hormone and luteinizing hormone
Thyrotroph produces
Adrenocorticotropic hormone
Thyroid-stimulating hormone
a-melanocyte stimulating hormone
Follicle-stimulating hormone
Prolactin is important for
Blood production
Sodium production
Milk production
Calcium production
B-FLAT:
LH
ACTH
Acidophils
Basophils
The pituitary gland begins to develop during the...
second trimester
fourth trimester
first trimester
third trimester
The neuropophysis develop from
endoderm
mesoderm
ectoderm
neuroectoderm
The adenohypophysis develop from
endoderm
mesoderm
ectoderm
neuroectoderm
A 23-year-old female patient is at your office for the first time, she came from a distal rural region because the only nurse there told her should have her neck checked as it's been growing in the last couple of months. There's no contributive medical history at the interview, from her physical exam it's remarkable her BP is 141/91mmHg, her eyes are within the orbicular fossa but seem they're almost protruding, S1 and S2 are rhythmic intense, almost pounding heart sounds and you can palpate her thyroid gland bilaterally. The serum antibodies you're certain will be present and positive in this patient are
Anti T3
TSI/Anti TSH
Anti TPO
Anti TRH
You request serum thyroid hormone levels, T3 and T4 elevated with decreased TSH, your clinical suspicion for diagnosis
Follicular carcinoma
Secondary hypothyroidism
Primary hypothyroidism
Quervain thyroiditis
The first line recommendation upon a thyroid mass (palpable thyroid gland)
Request CT scan
Request USG
Request screen serum T4
Request MRI
What results confirm the diagnosis in a patient with suspected hyperthyroidism?
Elevated T4
Elevated T3
Elevated T3 and T4
Elevated free T4, with low or stopped TSH
It occurs more frequently in women than men. With peak incidence between 20-40 years of age.
Hyperthyroidism
Hypothyroidism
Follicular carcinoma
Quervain thyroiditis
32-year-old patient with visual abnormalities and suspicion of pituitary disfunction was admitted to the hospital. An MRI of the brain revealed a 12mm sized pituitary adenoma. After resection of the tumor, a sample was sent to pathology. The cells observed were mainly acidophilic. Which celular type is most likely the adenoma be conformed of?
Corticotroph
Gonadotroph
Chromophobes
Mammatroph
Which of the following hormones is not manufactured by the pituitary gland but is stored in the pituitary gland?
Oxytocin
FSH
LH
Prolactin
Which of the following hormones resides in the Herring bodies of the pituitary gland?
Prolactin
ICSH
ACTH
Antidiuretic hormone
Where is the thyroid gland located?
Posterior neck
Anterior neck
Larynx
Hypothalamus
What is the structural unit of thyroid gland?
Follicle
Follicular cell
Neurons
Tyrosine
Which hormone is produced by the anterior pituitary?
TRH
TSH
TH
TGB
Which cells are stimulated by TRH?
Neurons in the PVN
Follicular cells
Thyrotropes
Hepatocytes
What does TSH activate?
Adenylate cyclase
Gq protein
Gs protein
pKA
What is the main building unit of the thyroglobulin?
pKA
Thyroid hormone
Thyroxine
Tyrosine
What is the substance is added to the thyroglobulin colloid during iodation?
Iodine
Iodide
Pendrin
Monoiodotyrosine
How many effects has the enzyme thyroid peroxidase?
1
2
3
4
TPO has three functions
Iodine oxidation
Iodination
Coupling
G stimulatory process
Which two substances collectively form TH
Thyroglobulin colloid and iodine
Tyrosine and thyroid peroxidase
Diiodotyrosine and monoiodotyrosine
Thyroxine and triiodothyronine
Which substance binds TH in the bloodstream?
Albumin
Thyroxine binding globulin
Thyroglobulin
Iodide
DIT + DIT =
T4
T3
T1
T2
DIT + MIT =
T1
T2
T3
T4
Iodine + MIT =
DIT
MIT
T3
T4
63-year-old male has a knee replacement surgery. After the surgery the patient develops symptoms compatible with Sheehan syndrome. Where is secreted the growth hormone?
Hypothalamus
Pituitary gland
Pancreas
Adrenal gland
28-year-old female start the anesthesiology residency. She has been informed that shifts are 24/48h. She realizes that she will have several stressing sleepless nights. Which of the following INHIBITS the secretion of the growth hormone by the anterior pituitary?
Stress
Starvation
Sleep
Somatomedins
B cells produce
Insulin
Somatostatin
Glucagon
Pancreatic polypeptide
D cells produce
Somatostatin
Glugagon
Insulin
Pancreatic polypeptide
Alpha cells produce
Somatostatin
Insulin
Pancreatic polypeptide
Glugacon
No insulinitis, amyloid deposition in islets
Type 1
Type 2
-
-
Insulin resistance in peripheral tissues, failure of compensation
Type 1
Type 2
-
-
Onset: usually childhood and adolescence
Type 1
Type 2
-
-
Vast majority are obese (80%)
Type 1
Type 2
-
-
Major linkage to MHC class II genes; also linked to polymorphisms in CTLA4 and PTPN22, and insulin gene VNTRs
Type 1
Type 2
-
-
Circulating islet autoantibodies
Type 1
Type 2
-
-
33-year-old woman comes to the physician for the evaluation of the white discharge form her nipples for 4 months. During this period, menses have occurred at irregular 30 to 45 day intervals and have lasted 3 to 10 days; menses had previously occurred at regular 30 day intervals with moderate flow. She has also had recurrent headaches that partially subside with ibuprofen. She has a healthy 5-year-old son. Which of the following is the most likely diagnosis?
GH adenoma
Pituitary adenoma
PRL adenoma
ACTH adenoma
55-year-old woman had a difficult labor 30 years earlier and had gone into coma followed by extensive uterine bleeding and hypotension. She had gradually recovered but had been unable to lactate and her periods had not returned. She lost her public and axillary hair. Her skin became dry and wrinkled she develop cold sensitivity, and her mental status deteriorated. She had memory loss and 3as lethargic. What is the most likely diagnosis?
Sheehan syndrome
Nelson syndrome
Cushing disease
Cushing syndrome
This enzyme is the rate-limiting step in the eventual formation of adrenal steroids:
3b-hydrosteroid dehydrogenase
21-B hydroxyls
Cholesterol desmolase
Aldosterone synthase
