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Worksheets

Endocrine System

Total questions: 67

Worksheet time: 35mins

Name
Class
Date
1.

A kidney donor suffered damaged to the renal artery during the surgery. Which of the following adrenal arteries could be?

a)

Superior adrenal artery

b)

Middle adrenal artery

c)

Inferior adrenal artery

d)

Inferior phrenic artery

2.

A 46-year-old woman is evaluated for voice changes after thyroid surgery. The patient was diagnosed with papillary thyroid cancer and subsequently underwent thyroidectomy. Immediately after the surgery, she noticed persistent hoarseness and dysphagia. Which nerve was most likely injured during the surgery.

a)

Right vagus nerve

b)

Lymphatic nodes

c)

Jugular vein

d)

Recurrent larygeal nerves

3.

The adrenal glands are ____ glands that produce a variety of hormones.

a)

Exocrine

b)

Endocrine

c)

Exterior

d)

Interior

4.

Where are the adrenal glands found?

a)

Pancrea

b)

Kidneys

c)

Galbladder

d)

Stomach

5.

What does the outer cortex of the adrenal gland produce?

a)

Steroid hormones

b)

Norepinephrine

c)

Dopamine

d)

Mineralocorticoids

6.

What does the inner medulla of the adrenal gland produce

a)

Androgens

b)

Glucocorticoids

c)

Steroid hormones

d)

Catecholamines

7.

Mineralocorticoids (aldosterone) effects:

a)

Regulate sodium

b)

Water reabsorption

c)

Potassium excretion

d)

All are correct

8.

Glucorticoids (cortisol) effects:

a)

Steroid hormones

b)

Glucose metabolism

c)

Water reabsorption

d)

Potassium absorption

9.

Adrenal sex hormones controls:

a)

Growth

b)

Blood flow

c)

Development

d)

Glucose

10.

What is the source for synthesis of all steroid hormones

a)

Glucose

b)

Epinephrine

c)

Dopamine

d)

Cholesterol

11.

Adrenal glands are

a)

Primary Retroperitoneal organs

b)

Intraperiotoneal organs

c)

Secondary Retroperitoneal organs

d)

Subperitoneal organs

12.

Mineralcorticoid synthesis occurs at the zone

a)

Glomerulosa

b)

Fasciculata

c)

Reticularis

d)

Chromaffin cells

13.

The main site of the synthesis of glucocorticoids is at the zone

a)

Reticularis

b)

Fasciculata

c)

Glomerulosa

d)

Chromaffin cells

14.

Arterial blood supply of adrenal glands

a)

Superior suprarenal artery

b)

Internal carotid artery

c)

Inferior suprarenal artery

d)

Middle suprarenal artery

15.

What does the medulla of the adrenal gland produce?

a)

Catecholamines

b)

Epinephrine

c)

Norepinephrine

d)

Steroid hormones

16.

Main site of androgen production

a)

Glomerulosa

b)

Reticularis

c)

Cortex

d)

Medulla

17.

What structure holds the pituitary gland?

a)

Hypothalamus

b)

Sella turcica

c)

Sphenoid bone

d)

Hypohyseal fossa

18.

Pituitary gland is also called

a)

hypophysis

b)

master gland

c)

PTH gland

19.

The anterior lobe carries out the important task of

a)

blood flow

b)

hormone production

c)

glucose regulation

d)

Gastrin production

20.

Acidophils are ____ and look ____ on H&E, while basophils are ____ and look ____ on H&E.

a)

acid loving and look pink; base loving and look blue-purple

b)

base loving and look pink; acid loving look blue-purple

c)

acid loving and look pink; base loving look pink

d)

base loving and look blue-purple; acid loving look blue-purple

21.

Acidophils include two main hormones -producing cells-

a)

Somatrophs and Thyrotroph

b)

Thyrotroph and Gonadotroph

c)

Corticotroph and Mammatroph

d)

Mammatroph and Somatotroph

22.

Somatotroph produces

a)

Growth hormone

b)

Prolactin

c)

Thyroid-stimulating hormone

d)

Follicle-stimulating hormone and luteinizing hormone

23.

Mammotroph produces

a)

Growth hormone

b)

Adrenocroticotropic hormone and a-melanocyte stimulating hormone

c)

Prolactin

d)

Thyroid-stimulating hormone

24.

Gonadotroph produces

a)

Prolactin

b)

Follicle-stimulating hormone and luteinizing hormone

c)

Thyroid-stimulating hormone

d)

Adrenocorticotropic hormone and a-melanocyte stimulating hormone

25.

Corticotroph produces

a)

Adrenocorticotropic hormone and a-melanocyte stimulating hormone

b)

Prolactin

c)

Growth hormone

d)

Follicle-stimulating hormone and luteinizing hormone

26.

Thyrotroph produces

a)

Adrenocorticotropic hormone

b)

Thyroid-stimulating hormone

c)

a-melanocyte stimulating hormone

d)

Follicle-stimulating hormone

27.

Prolactin is important for

a)

Blood production

b)

Sodium production

c)

Milk production

d)

Calcium production

28.

B-FLAT:

a)

LH

b)

ACTH

c)

Acidophils

d)

Basophils

29.

The pituitary gland begins to develop during the...

a)

second trimester

b)

fourth trimester

c)

first trimester

d)

third trimester

30.

The neuropophysis develop from

a)

endoderm

b)

mesoderm

c)

ectoderm

d)

neuroectoderm

31.

The adenohypophysis develop from

a)

endoderm

b)

mesoderm

c)

ectoderm

d)

neuroectoderm

32.

A 23-year-old female patient is at your office for the first time, she came from a distal rural region because the only nurse there told her should have her neck checked as it's been growing in the last couple of months. There's no contributive medical history at the interview, from her physical exam it's remarkable her BP is 141/91mmHg, her eyes are within the orbicular fossa but seem they're almost protruding, S1 and S2 are rhythmic intense, almost pounding heart sounds and you can palpate her thyroid gland bilaterally. The serum antibodies you're certain will be present and positive in this patient are

a)

Anti T3

b)

TSI/Anti TSH

c)

Anti TPO

d)

Anti TRH

33.

You request serum thyroid hormone levels, T3 and T4 elevated with decreased TSH, your clinical suspicion for diagnosis

a)

Follicular carcinoma

b)

Secondary hypothyroidism

c)

Primary hypothyroidism

d)

Quervain thyroiditis

34.

The first line recommendation upon a thyroid mass (palpable thyroid gland)

a)

Request CT scan

b)

Request USG

c)

Request screen serum T4

d)

Request MRI

35.

What results confirm the diagnosis in a patient with suspected hyperthyroidism?

a)

Elevated T4

b)

Elevated T3

c)

Elevated T3 and T4

d)

Elevated free T4, with low or stopped TSH

36.

It occurs more frequently in women than men. With peak incidence between 20-40 years of age.

a)

Hyperthyroidism

b)

Hypothyroidism

c)

Follicular carcinoma

d)

Quervain thyroiditis

37.

32-year-old patient with visual abnormalities and suspicion of pituitary disfunction was admitted to the hospital. An MRI of the brain revealed a 12mm sized pituitary adenoma. After resection of the tumor, a sample was sent to pathology. The cells observed were mainly acidophilic. Which celular type is most likely the adenoma be conformed of?

a)

Corticotroph

b)

Gonadotroph

c)

Chromophobes

d)

Mammatroph

38.

Which of the following hormones is not manufactured by the pituitary gland but is stored in the pituitary gland?

a)

Oxytocin

b)

FSH

c)

LH

d)

Prolactin

39.

Which of the following hormones resides in the Herring bodies of the pituitary gland?

a)

Prolactin

b)

ICSH

c)

ACTH

d)

Antidiuretic hormone

40.

Where is the thyroid gland located?

a)

Posterior neck

b)

Anterior neck

c)

Larynx

d)

Hypothalamus

41.

What is the structural unit of thyroid gland?

a)

Follicle

b)

Follicular cell

c)

Neurons

d)

Tyrosine

42.

Which hormone is produced by the anterior pituitary?

a)

TRH

b)

TSH

c)

TH

d)

TGB

43.

Which cells are stimulated by TRH?

a)

Neurons in the PVN

b)

Follicular cells

c)

Thyrotropes

d)

Hepatocytes

44.

What does TSH activate?

a)

Adenylate cyclase

b)

Gq protein

c)

Gs protein

d)

pKA

45.

What is the main building unit of the thyroglobulin?

a)

pKA

b)

Thyroid hormone

c)

Thyroxine

d)

Tyrosine

46.

What is the substance is added to the thyroglobulin colloid during iodation?

a)

Iodine

b)

Iodide

c)

Pendrin

d)

Monoiodotyrosine

47.

How many effects has the enzyme thyroid peroxidase?

a)

1

b)

2

c)

3

d)

4

48.

TPO has three functions

a)

Iodine oxidation

b)

Iodination

c)

Coupling

d)

G stimulatory process

49.

Which two substances collectively form TH

a)

Thyroglobulin colloid and iodine

b)

Tyrosine and thyroid peroxidase

c)

Diiodotyrosine and monoiodotyrosine

d)

Thyroxine and triiodothyronine

50.

Which substance binds TH in the bloodstream?

a)

Albumin

b)

Thyroxine binding globulin

c)

Thyroglobulin

d)

Iodide

51.

DIT + DIT =

a)

T4

b)

T3

c)

T1

d)

T2

52.

DIT + MIT =

a)

T1

b)

T2

c)

T3

d)

T4

53.

Iodine + MIT =

a)

DIT

b)

MIT

c)

T3

d)

T4

54.

63-year-old male has a knee replacement surgery. After the surgery the patient develops symptoms compatible with Sheehan syndrome. Where is secreted the growth hormone?

a)

Hypothalamus

b)

Pituitary gland

c)

Pancreas

d)

Adrenal gland

55.

28-year-old female start the anesthesiology residency. She has been informed that shifts are 24/48h. She realizes that she will have several stressing sleepless nights. Which of the following INHIBITS the secretion of the growth hormone by the anterior pituitary?

a)

Stress

b)

Starvation

c)

Sleep

d)

Somatomedins

56.

B cells produce

a)

Insulin

b)

Somatostatin

c)

Glucagon

d)

Pancreatic polypeptide

57.

D cells produce

a)

Somatostatin

b)

Glugagon

c)

Insulin

d)

Pancreatic polypeptide

58.

Alpha cells produce

a)

Somatostatin

b)

Insulin

c)

Pancreatic polypeptide

d)

Glugacon

59.

No insulinitis, amyloid deposition in islets

a)

Type 1

b)

Type 2

c)

-

d)

-

60.

Insulin resistance in peripheral tissues, failure of compensation

a)

Type 1

b)

Type 2

c)

-

d)

-

61.

Onset: usually childhood and adolescence

a)

Type 1

b)

Type 2

c)

-

d)

-

62.

Vast majority are obese (80%)

a)

Type 1

b)

Type 2

c)

-

d)

-

63.

Major linkage to MHC class II genes; also linked to polymorphisms in CTLA4 and PTPN22, and insulin gene VNTRs

a)

Type 1

b)

Type 2

c)

-

d)

-

64.

Circulating islet autoantibodies

a)

Type 1

b)

Type 2

c)

-

d)

-

65.

33-year-old woman comes to the physician for the evaluation of the white discharge form her nipples for 4 months. During this period, menses have occurred at irregular 30 to 45 day intervals and have lasted 3 to 10 days; menses had previously occurred at regular 30 day intervals with moderate flow. She has also had recurrent headaches that partially subside with ibuprofen. She has a healthy 5-year-old son. Which of the following is the most likely diagnosis?

a)

GH adenoma

b)

Pituitary adenoma

c)

PRL adenoma

d)

ACTH adenoma

66.

55-year-old woman had a difficult labor 30 years earlier and had gone into coma followed by extensive uterine bleeding and hypotension. She had gradually recovered but had been unable to lactate and her periods had not returned. She lost her public and axillary hair. Her skin became dry and wrinkled she develop cold sensitivity, and her mental status deteriorated. She had memory loss and 3as lethargic. What is the most likely diagnosis?

a)

Sheehan syndrome

b)

Nelson syndrome

c)

Cushing disease

d)

Cushing syndrome

67.

This enzyme is the rate-limiting step in the eventual formation of adrenal steroids:

a)

3b-hydrosteroid dehydrogenase

b)

21-B hydroxyls

c)

Cholesterol desmolase

d)

Aldosterone synthase