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Biological explanation of Schizophrenia

Total questions: 13

Worksheet time: 7mins

Name
Class
Date
1.

What are family studies?

a)

Close family members are compared on the same trait to determine a genetic basis

b)

Twins are compared on the same trait to determine a genetic basis

c)

Adopted children are compared to their biological family on the same trait to determine a genetic basis.

2.

What term is being described: the proportion of pairs where both individuals share a certain characteristic.

a)

Coordination rate

b)

Concordance rate

c)

Cooperation rate

3.

According to Gottesman (1991) what percentage of MZ twins had severe Schizophrenia?

a)

12-28%

b)

75-91%

c)

17-33%

d)

85-97%

4.

What is meant by 'candidate genes'?

a)

A genetic mutation is responsible for the disorder

b)

Genes have nothing to do with the onset of the disorder

c)

Multiple genes are responsible for a disorder

d)

A single gene is responsible for a disorder

5.

What is meant by a neural correlate?

a)

A particular area of the brain is associated with a particular behaviour

b)

A particular area of the brain is not associated with a particular behaviour

c)

A particular gene is associated with a certain behaviour

6.

Which statement best describes the neurotransmitter dopamine?

a)

It is an inhibitory neurotransmitter

b)

It is an excitatory neurotransmitter associated with the pleasure response

c)

It is associated with the sleep-wake cycle

7.

What does the dopamine hypothesis state about the onset of Schizophrenia?

a)

The brain of SZ patients produce no dopamine

b)

The brain of SZ patients produces different levels of dopamine compared to non SZ patients.

c)

The brain of SZ patients produces different levels of serotonin compared to non SZ patients

d)

The brain of SZ patients produce no serotonin

8.

What did the original dopamine hypothesis propose?

a)

High levels of dopamine in the subcortex

b)

High levels of dopamine in the brain stem

c)

Low levels of dopamine in the subcortex

d)

High levels of dopamine in the cortex

9.

What did the more recent dopamine hypothesis focus on?

a)

High levels of dopamine in the subcortex

b)

High levels of dopamine in the brain stem

c)

Low levels of dopamine in the cortex

d)

High levels of dopamine in the cortex

10.

According to the original dopamine hypothesis, too high levels of dopamine in Broca's area could be associated with what symptom of Schizophrenia?

a)

Hallucinations

b)

Speech Poverty

c)

Avolition

d)

Delusions

11.

Low levels of dopamine in the ventral striatum is associated with what negative symptom of Schizophrenia?

a)

Hallucinations

b)

Delusions

c)

Avolition

d)

Speech poverty

12.

Low levels of dopamine activity in which area of the brain is linked to auditory hallucinations?

a)

Ventral striatum

b)

Superior temporal gyrus

c)

Cortex

d)

Subcortex

13.

What is a problem with the neural correlates explanation?

a)

Evidence regarding which genes are involved in SZ is too diverse

b)

It relies on brain scanning evidence

c)

Correlation-causation problem