A 13 yo female presents to your ED with unilateral facial swelling x 1 week. Her mother is very worried because along with the facial swelling she has begun drooling from the left corner of her mouth. Her vaccines are up-to-date however she received her flu shot this year. She has no cough. On examination, she has mildly tender left cheek swelling and mild left upper and lower facial weakness. She has no neck pain or tenderness. The remainder of her exam is unremarkable including ENT exam. Vital signs are BP 112/74, HR 70bpm, RR 14, Sat 100% on RA, T 38.5C (101.3F). In the exam room she is smiling and playing with her older sibling. Which of the following do you expect to be abnormal.

A 42 year old male with known HIV presents to the Emergency Department with a chief complaint of headache for 2 weeks. He reports he has been out of his HIV medications for the last 2 months, but does not recall the names. Vital signs are: BP 100/67 HR 92 RR 16 T 100.6F (38.1C). Laboratory testing is significant for a CD4 count of 87. An image from a noncontrast CT head is shown. Which of the following is the most likely etiology of his headache?

A 13-year-old boy presents for evaluation of a fever for 2 days. His parents also note decreased appetite and malaise. His vitals on arrival to the emergency department are T 38.6°C, HR 123 bpm, BP 90/50 mm Hg, and 98% saturation on room air. His physical examination is notable for the skin findings shown above and shallow ulcers on the tongue and buccal mucosa. Which of the following is a complication of this patient’s condition?

Which of the following patients who tested positive for SARS-CoV-2 is most likely to benefit from monoclonal antibody treatment?

An 18-year-old college student with a history of HIV (CD4⁺ 250) presents to the ED with headache, fever, and stiff neck for two days. He thought he had a cold and has been taking acetaminophen without relief of his headache. Vital signs are T 102.38°F (39.1°C), BP 100/50 mm Hg, HR 140 bpm, and RR 30/min. He is sleepy but arousable. On exam, you place the patient’s right hip and knee into a flexed position and then proceed to extend the knee. The patient winces when the knee is just beyond 90 degrees of flexion. You also note petechiae on his trunk and extremities with one small area on his right forearm that looks like a purple patch with a gray necrotic center. Which of the following is the most likely diagnosis?

A 67-year-old female with history of mitral valve prolapse presents to the Emergency Department with generalized malaise, 20 pound weight loss and intermittent fevers for the past three weeks after simple dental extraction. Her vitals are BP 145/88, P 89, RR 15 O2S at 98%, T101.5 (38.6C). Other than a mid-to-late systolic click at the cardiac apex, her physical exam is largely unremarkable. EKG and chest x-ray are normal. Blood cultures in addition to labs studies are drawn and broad-spectrum antibiotics started. What is the next best step in managing this patient?

A 33-year-old male with a history of HIV presents to the emergency department with fever and generalized weakness. He is not compliant with his medications and his last CD4 count was less than 50 cells/µL. Laboratory analysis is significant for pancytopenia. What is the most likely etiology of this patient’s presentation?

A 53-year old patient is brought in by ambulance to the Emergency Department from the street for altered mental status. He is disoriented and yelling about "the mafia" and "ghosts", with waxing and waning belligerence. Vitals signs are BP 141/89, P 118, R 16, T 101.2F (38.4C), O2 saturation 99%RA. After chemical sedation, the patient was sent to radiology for a CT scan of the head. The technician accidentally completed the CT scan with contrast, which showed several ring-enhancing lesions. A rapid HIV test results positive. Which of the following is considered first-line therapy in the treatment of this patient?

A 34 year old male presents to the Emergency Department with general feeling of malaise, fatigue, and headaches for one week. The patient denies pharyngitis or cough. The patient denies any past medical or surgical history. Vitals signs are: BP 120/87, HR 102, RR 14, T 101.2F (38.4C). Social history is significant for unprotected sex with multiple male and female partners. Which of the following is TRUE regarding this patient's likely underlying disease process?