WorksheetsCC1-PREFINAL EXAM
Total questions: 36
Worksheet time: 40mins
Which of the following statements about lipids is incorrect?
Lipids are compounds that are insoluble in water and other polar solvents.
It is soluble in organic solvents like chloroform, methanol, and ether.
Other than glucose, which is the main source of energy in the body, lipids also serve as primary sources of fuel or energy in the body.
It also contributes to antigenicity, which means it contributes to the immune system. In fact among the cell components lipids are more immunogenic than proteins.
Among these types or classes of lipids, which are NOT a source of energy for animals?
Cholesterol
Triglycerides
Fatty acid
Phospholipids
Which of the statements is incorrect?
One portion of the molecule is hydrophobic, and another is hydrophilic.
Cholesteryl ester is the esterified form of cholesterol.
Not all cholesterol in the intestine is present in an unesterified or non-esterified form because some is esterified.
Cholesterol ester is only found in plasma and serum.
Which of the statements is correct?
HMG-coA can come from cytoplasmic oxidation of ethanol by acetyl-CoA synthetase.
Lanosterol is the first of the sterols to be formed during the synthesis of cholesterol.
Acetyl-CoA is converted to mevalonate by the enzyme HMG-CoA reductase.
All statements are correct
These are constituents of phospholipids and TAGs. They are mainly derived from the hydrolysis of TAGs in adipose tissue.
Fatty Acids
Glycolipids
Glucose
Cholesterol
It allows effective gas exchange and prevents alveolar collapse by reducing the surface tension of the alveoli in the lungs. It is also involved in cellular metabolism and blood coagulation.
Fatty Acids
Glycolipids
Phospholipids
Lipoproteins
decreased levels of LDL because of defect in apo-B gene (genetic).
Hypobetalipoproteinemia
Familial Dysbetalipoproteinemia
Hypoalphalipoproteinemia
Tangier Disease
Which of the following describes Tangier Disease?
Mutation in the ABCA1 gene on chromosome 8
Defect in Apo-B gene
Mutations in LCAT, Apo A-1, and ABCA1 gene transporters
None of the above
Elevation of TAGs on plasma is also indicative of elevation of
Cholesterol
Chylomicrons
LDL
Lipoproteins
A classification and characteristics of lipoprotein that its principal function is to transport exogenous TAG
CM
HDL
VLDL
LDL
During the LP test during blood collection, the ____recommends that the patient be seated for 5 minutes to prevent hemoconcentration.
ADA
NCEP
CLSI
DOH
Chylomicrons are cleared from the circulation ___ hrs after eating.
9–12
10-14
8-12
6-9
9
A classification and characteristics of lipoprotein that its principal function is to transport endogenous TAG.
CM
LDL
IDL
VLDL
HDL
This is a potent activator of the enzyme lipoprotein lipase.
Apo A
Apo B
Apo C
Apo D
Long chains of FA and 2-MAG, as acted upon by the enzyme?
CCK
ACAT
PANCREATIC LIPASE
FATTY ACYL TRANSFERASE
This functions in the hydrolysis of phospholipids and TAGs in lipoproteins.
Pancreatic lipase
lipoprotein lipase)
Endothelial lipase
LCAT
This is a distinct class of lipoprotein because it is structurally similar to LDL because these two possess one molecule of Apo B-100 per particle.
IDL
LPa
VLDL
LP x
Which of the following does not belong to the group?
Parek-Jung
Schoenheimer-Sperry
Abell-Kendall
Sperry-Webb
The purpose of sulfuric acid in the Salkowski/Zak method?
Color development
Precipitation
Saponification
Alkaline hydrolysis
The first step in the digestion of lipids is the
Hydrolysis
Emulsification
Adsorption
Digestion
It is considered to be the largest in diameter and the least dense of all the lipoproteins.
CM
VLDL
LDL
HDL
IDL
The higher the lipid content, the less dense the lipoprotein particle. Therefore,
The closer they migrate to the middle of the tube,
The closer they migrate to the top of the tube,
The closer they migrate to the bottom of the tube,
NOTA
AOTA
This is considered to be a non-exchangeable apolipoprotein.
Apo A
Apo B
Apo C
Apo D
This is the complete blockage of blood supply to the heart muscle, which results in heart attack or cardiac arrest.
Angina
Cerebrovascular disease
Myocardial infarction
Coronary heart disease
When the lipoproteins are measured by this method, plasma is the preferred specimen.
Ultracentrifugation
Electrophoretic Methods
Both A and B.
B only
Lipid profile tests are performed all on machines except for
HDL
LDL
VLDL
B & C
A and C.
In combined hyperlipidemia, all these analytes will be elevated except?
Total Cholesterol
TAG's
HDL
LDL
None of the above
When we have an isolated increase in cholesterol, is this also indicative of increased
LDL
VLDL
HDL
CM
NONE OF THE ABOVE
A local anemia is where there is decreased blood supply to a particular organ.
Lipidemia
Anemia
Ischemia
Saminamena
A and B.
This is a specific form of arteriosclerosis. It also has thickening and hardening of the walls of arteries due to the deposition of cholesterol on the surface of blood vessels.
(a)
This is the most important disease affecting the heart. It is an atherosclerotic condition affecting the coronary arteries.
(a)
Which conditions are associated with plaque development?
Peripheral vascular disease
Coronary heart disease
Cerebrovascular disease
Myocardial infarction
All of the above
This is a condition where there is cholesterol deposition in the skin.
(a)
Otherwise known as type III hyperlipoproteinemia, it is associated with the presence of a very rare form of apolipoprotein, apolipoprotein E2/2.
(a)
A condition that has decreased levels of LDL because of a defect in the apo-B gene
(a)
Discuss and differentiate lipoproteins (CM, VLDL, LDL, & HDL).
