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MLT552 QUIZ 1

Total questions: 15

Worksheet time: 7mins

Name
Class
Date
1.

The number of human chromosomes is (a)   .

2.

Each chromosome is made up of DNA tightly coiled many times around proteins called (a)   that support its structure.

3.
The ___________ holds the replicated sister chromatids together.
a)
centriole
b)
chromosomes
c)
centromere
d)
cycles
4.

Which of the following represents the correct order of the phases of mitosis?

a)

prophase -> anaphase -> metaphase -> telophase

b)

prophase -> metaphase -> anaphase -> telophase

c)

prophase -> metaphase -> telophase -> anaphase

d)

metaphase -> prophase -> telophase -> anaphase

5.

Which of the following statements about chromosome is INCORRECT?

a)

A chromosome consists of 2 sister chromatids.

b)

The classification of human chromosome is based on the position of the centromere on the chromosome.

c)

All chromosomes come from the same parent.

d)

Chromosome is found within the nucleus.

6.

Karyotyping is an orderly arrangement of the chromosomes in pairs based on

a)

size

b)

banding pattern

c)

location of telomere

d)

location of centromere

7.

Chromosomes that are paired by size and content are called (a)   chromosomes.

8.

Human eggs and sperm are _____, and each has ____ chromosomes.

a)

diploid, 23

b)

diploid, 46

c)

haploid, 23

d)

haploid, 46

9.

What is aneuploidy?

a)

Abnormal structure of a chromosome.

b)

Abnormal number of chromosomes in a cell.

c)

Exchange of chromosomal material between chromosomes.

d)

More than two sets of chromosomes in a cell.

10.

What is the most likely mechanisms that can cause aneuploidy?

a)

Mutation.

b)

Fetilisation.

c)

Non-disjunction.

d)

Meiosis.

11.

Polyploidy refers to

a)

the presence of more than two of a certain chromosome.

b)

more than two of a certain chromosome.

c)

the presence of multiple sets of chromosome.

d)

the general term for condition such as Down or Turner Syndrome.

12.

What is the karyotype notation for a female with triploidy?

a)

138,XXY.

b)

69,XXY.

c)

69,XXX.

d)

138,XXX.

13.

Which syndrome is also known as Trisomy 18?

a)

Down Syndrome

b)

Edwards syndrome

c)

Patau syndrome

d)

Turner syndrome

14.

Based on the International Cytogenetic System Nomenclature (ICSN), write the karyotype.

(a)  

15.

Which chromosomal rearrangement involves one chromosome attaching to another at the centromere?

a)

Robertsonian translocation

b)

Reciprocal translocation

c)

Inversion

d)

Deletion