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Worksheets

DDS Powders/Granules/Capsules

Total questions: 87

Worksheet time: 47mins

Name
Class
Date
1.

A mixture of finely divided drugs from comminution of chemicals in dry form

a)

Powder

b)

Granules

c)

Capsule

d)

Tablet

2.

Powder may be used internally or externally

a)

True

b)

False

3.

Which of these are the advantages of powders

a)

Flexibility of conpoinding

b)

Good chemical stability

c)

Rapid dispersion of ingredients

d)

Inaccuracy of do

4.

Particle size of powder

a)

0.1 to 10 micron

b)

0.2 to 10 micron

c)

0.3 to 10 micron

d)

0.4 to 10 micron

5.

Size of particles are often expressed as a number which corresponds to Mesh screen size

a)

True

b)

False

6.

Screen size indicates the number of openings in the mesh screen per inch

a)

True

b)

False

7.

Medicated powders usually present in large quantities

a)

Bulk powder

b)

Divided powder

8.

Known as chartula/chartulae

a)

Bulk powder

b)

Divided powder

9.

Dispensed in individualized doses

a)

Bulk powder

b)

Divided powder

10.

Continuous rubbing or grinding of the powder in a mortar and pestle

a)

Trituration

b)

Levigation

c)

Pulverization by intervention

11.

Often used to prevent a gritty feel when solids are incorporated into dermatologic or opthalmic ointments and suspensions

a)

Trituration

b)

Levigation

c)

Pulverization by intervention

12.

Which of these are used as levigating agent

a)

Mineral oil

b)

Glycerin

c)

Alcohol

d)

Acetone

13.

Product becomes solid when adding a levigating agent

a)

True

b)

False

14.

Uses an additional materials in which the material is soluble

a)

Trituration

b)

Levigation

c)

Pulverization by intervention

15.

Examples of volatile solvent

a)

Glycerin

b)

Mineral oil

c)

Acetone

d)

Alcohol

16.

4 ways of comminuting

a)

Trituration

b)

Levigation

c)

Pulverization by intervention

d)

Mechanically by grinder and mill

17.

We use geometric dilution for non potent preparations

a)

True

b)

False

18.

Use ____ mortar with a rough inner surface if comminution is desired

a)

Porcelain or ceramic

b)

Glass mortar

19.

Preferable for chemicals that stain a porcelain or ceramic surface

a)

Glass mortar

b)

Ceramic or porcelain mortar

20.

Useful for solid substances that liquefy or form eutectic mixtures

a)

Tumbling

b)

Spatulation

c)

Trituration

d)

Sifting

21.

___ pfevents eutexia with aspirin, phenylsalicylate, and ofher troublesome compounds

a)

Tartaric acid

b)

Salicylic acid

c)

Silicic acid

d)

Citric acid

22.

Geometric dilution ensures uniform distribution

a)

True

b)

False

23.

Results in light, fluffy product

a)

Spatulation

b)

Trituration

c)

Sifting

d)

Tumbling

24.

Process of mixing powders in a large container rotated by a motorized process

a)

Sifting

b)

Tumbling

c)

Trituration

d)

Spatulation

25.

How do we divide powders?

a)

Block and divide method

b)

Block and multiply

26.

An opaque paper with no moisture-resistant property

a)

Vegetable parchment

b)

White bond paper

c)

Glassine paper

d)

Waxed paper

27.

A thin, semi-opaque, moisture resistant paler

a)

Vegetable parchment

b)

White bond paper

c)

Glassine paper

d)

Waxed paper

28.

A glazed, transparent, moisture-resistant paper

a)

Vegetable parchment

b)

White bond paper

c)

Glassine paper

d)

Waxed paper

29.

Transparent water proof paper

a)

Vegetable parchment

b)

White bond paper

c)

Glassine paperr

d)

Waxed paper

30.

Dosage form composed of dry aggregates of powder particles

a)

powders

b)

granules

c)

capsules

31.

good choice for compressing tablet

a)

powders

b)

granules

32.

why granules are good choice for compressing tablet?

a)

because they flow well

b)

less stable

33.

due to less surface area, granules are more stable and less likely to harden

a)

true

b)

false

34.

powders are difficult to make solution

a)

true

b)

false

35.

poor compressibility

a)

granules

b)

powder

36.

generate less dust on handlingp

a)

powders

b)

granules

37.

more uniformity of content dosing

a)

granules

b)

powders

38.

relatively simple method of processing/formilation

a)

powder

b)

granule

39.

heating the ingredients sufficiently to drive off water of hydration from the uneffloresced citric acid

a)

dry method

b)

wet method

40.

addition of small amounts of water to the dry salts to obtain workable mass

a)

dry method

b)

wet method

41.

loose firmness and crumble

a)

citric acid

b)

tartaric acid

42.

sticky and diff to granulate

a)

tartaric acid

b)

citric acid

43.

ratio of citric acid and tartaric acid

a)

1:1

b)

1:2

c)

2:1

44.

synonym for dibasic sodium phosphate

(a)  

45.

use of sodium phosphate

a)

analgesic

b)

antithrombotic

c)

antipyretic

d)

saline laxative

46.

method of preparation for sodium phosphate

a)

block and divide method

b)

dry fusion method

c)

punch method

47.

appropriate container for granules

a)

wide mouth bottle

b)

resealable plastic

c)

empty capsule shell

48.

storage condition for granules

a)

protect it against humidity and air

b)

store at room temperature

c)

store at cool temperature

49.

API of sodium phosphate granule

a)

sodium phosphate

b)

sodium bicarbonate

c)

citric acid

d)

tartaric acid

50.

solid dosage form in which the drug substance is enclosed in either a hard or soft, soluble container or shell of a suitable form of gelatin

a)

granule

b)

capsule

c)

tablet

d)

powder

51.

types of capsule

a)

hard gelatin capsule

b)

soft gelatin capsule

52.

a soft, globular, gelatin shell thicker than HGC

a)

hard gelatin capsule

b)

soft gelatin capsule

53.

capsule is more preferred than tablet

a)

true

b)

false

54.

consists of two sections

a)

cap

b)

body

c)

head

d)

tail

55.

obtained by the partial hydrolysis of collagen dervied from the skin, white connectice tissue, and bones of animals

a)

Gelatin

b)

capsule

c)

tablet

d)

granule

56.

obtained from bones and animal skins by alkaline processing

a)

type A gelatin

b)

type B gelatin

57.

referred to ad "soft-elastic capsule"

a)

hard gelatin capsule

b)

soft felatin

58.

cellulose materials for vegetarian (gelatin component)

a)

type A

b)

type B

c)

hydroxypropyl cellulose

59.

components of empty gelatin shells are made up of:

a)

gelatin

b)

sugar

c)

water

d)

colorants

e)

opacifying agents

60.

water from capsule ranges from

(a)  

61.

colorants have:

a)

water soluble dyes

b)

oil dye

c)

pigment

d)

color

62.

example pf water soluble dye

a)

iron oxide

b)

erythrosine

63.

example of pigment

a)

erythrosine

b)

magnesium oxide

c)

iron oxide

d)

titanium dioxide

64.

makes the capsule opaque to provide protection against light

a)

gelatin

b)

water

c)

opacifying agent

d)

colorant

65.

example of an opacifying agent

a)

iron oxide

b)

titanium dioxide

c)

erythrosine

d)

magnesium oxide

66.

the USP permits the use of ___to prevent decomposition of manufacture

a)

0.15% sulfur dioxide

b)

0.25% sulfur dioxide

c)

0.35% sulfur dioxide

67.

the cap os meant to enclose the powder

a)

true

b)

false

68.

common fillers used for hard gelatin capsuke

a)

lactose

b)

iron oxide

c)

erythrosine

d)

titanium dioxide

69.

smallest capsule size

a)

000

b)

1

c)

00

d)

5

70.

Mostly added lubricant on capsules

a)

Lactose

b)

Iron oxide

c)

Titanium oxide

d)

Magnesium stearate

71.

Magnesium stearate is water proof (delays absorption of the process)

a)

True

b)

False

72.

Wetting agent is added in the preparation of capsule

a)

True

b)

False

73.

Example of wetting agent

a)

Titanium dioxide

b)

Magnesium stearate

c)

Sodium lauryl sulfate

74.

check if capsules have been filled

a)

locked

b)

uniformity

c)

extent of fill

75.

hard capsules should be stored kn ___ container

a)

well-closed contianer

b)

tightly closed container

76.

ensures that prpduct is tightly closed and locked

a)

uniformity

b)

extent of fill

c)

locked

77.

checks for uniformity in appearance and color

a)

uniformity

b)

extent of fill

c)

locked

78.

more moisture

a)

soft gelatin capsule

b)

dry-filled capsule

c)

hard gelatin capsule

d)

soft elastic capsule

79.

when humidity is low, the capsules become brittle

a)

true

b)

false

80.

when humidity is high, capsules become

flaccid and shapeless

a)

true

b)

false

81.

storage at high temperatures do not affect the quality of hard gelatin capsule

a)

true

b)

false

82.

SEC contains more moisture than hard gelatin

a)

true

b)

false

83.

common added preservatives for capsule

a)

parabens

b)

glycerin

c)

sorbitol

84.

inside soft gelatin capsule, you can add

a)

paste

b)

dried powders

c)

perforated tablet

85.

soft gelatin are prepared by

a)

gelatin (35-45%)

b)

plasticizer (15-25%)

c)

water (40%)

86.

water is made up of

a)

35-45%

b)

15-25%

c)

40%

87.

Dosage form composed of dry aggregates of powder particles

a)

powders

b)

granules

c)

capsules