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UMMC Cytotoxic & Parenteral Nutrition Workshop 2022

Total questions: 28

Worksheet time: 11mins

Name
Class
Date
1.

Which statement is FALSE about cleanroom?

a)

A clean space that eliminates bacterial contamination only

b)

An isolated environment strictly controlled with respect to temperature, humidity and differential pressure

c)

It must have good ventilation

d)

The surfaces of a cleanroom must be smooth and easy to clean

2.

What are the types of disinfectant used in a cleanroom?

i) Water for injection

ii) Alcohol based

iii) Quaternary ammonium

iv) Phenolic based

a)

i, ii and iii

b)

i, iii and iv

c)

ii, iii and iv

d)

i, ii and iv

3.

What is the appropriate area for preparing cytotoxic drugs?

a)

At the patient's bedside

b)

Under Biosafety Cabinet (BSC) in the cleanroom facility

c)

In a positive pressure cleanroom facility

d)

At the meeting room with the personal protective equipment (PPE)

4.

What is the terminology used to describe the chemotherapy used to destroy the leftover malignant cells after the tumour is being removed surgically?

a)

Adjuvant

b)

Neoadjuvant

c)

Palliative

d)

Induction

5.

Which electrolytes are included in the Cisplatin hydration?

a)

Magnesium sulfate and Calcium gluconate

b)

Potassium chloride and Calcium gluconate

c)

Potassium dihydrogen phosphate and Calcium gluconate

d)

Magnesium sulfate and Potassium chloride

6.

Patient TSJ is diagnosed with stage 4 lung cancer and is prescribed with a regimen containing IV Pemetrexed 500mg/m2. Patient's height is 170cm and weight 82kg. Assuming both renal and hepatic functions are normal, calculate the required Pemetrexed dose

a)

890mg

b)

985mg

c)

925mg

d)

750mg

7.

What is the definition of near misses?

a)

Any events when you missed a step in the standard operating procedures

b)

Any errors detected at the patient area

c)

Any errors that is overlooked during screening of protocols

d)

Any errors detected in the pharmacy area before dispensing the medications

8.

How do you prevent an error from happening?

i) Follow the standard operating procedures

ii) Always have an independent 2 point check

iii) When in doubt, discuss it with your supervisor

iv) Take a shorter work process to improve efficiency

a)

i & iv

b)

i, iii & iv

c)

i, ii & iii

d)

ii & iii

9.

When a medication error occurs, what should be done first?

a)

Keep quiet & continue work

b)

Investigate the medication error thoroughly & objectively

c)

Find the person who caused the error & give appropriate punishment

d)

An error report will need to be filled through your supervisor after thorough investigation is done objectively

10.

From the picture above, who is the owner of the initial?

a)

First checker (checking label & worksheet)

b)

Final checker (checking bag & product)

c)

Drug reconstitution staff

d)

Second check for packing

11.

Which of the following needs the auxiliary label of “roll the syringe before use”?

a)

Subcutaneous Methotrexate

b)

Subcutaneous Bortezomib

c)

Subcutaneous Azacitidine

d)

Intramuscular Bleomycin

12.

What are the chronological steps for cleaning before leaving sterile complex in the evening?

a)

Water-> Decon-> Water-> Alcohol

b)

Water-> Alcohol

c)

Water-> Alcohol-> Water-> Decon

d)

Water-> Alcohol-> Water-> Hydrogen peroxide

13.

Which of the following DOES NOT need an auxillary label of 'DO NOT SHAKE'

a)

Paclitaxel

b)

Doxorubicin liposomal

c)

Bevacizumab

d)

Pemetrexed

14.

For public patients, which medication requires payment?

i) Carboplatin

ii) Gemcitabine

iii) Irinotecan

iv) Oxaliplatin

a)

i & ii

b)

ii & iv

c)

ii, iii & iv

d)

ii only

15.

Which drugs need a 0.2micron filter tubing?

i) paclitaxel

ii) Infliximab

iii) Aflibercept

iv) Ramucirumab

a)

i, ii & iii

b)

i only

c)

i, iii & iv

d)

All of the above

16.

What do we need to check upon receiving a protocol?

i) Medication payment

ii) Medication dose

iii) Doctor's signature & stamp

iv) Chemotherapy date

a)

ii, iii & iv

b)

iii & iv

c)

iii only

d)

All of the above

17.

Scenario:

Pharmacist Assistant “B” accidentally drops a pre-diluted vial of Ifosfamide on the floor in control room, therefore a spill has occurred. You are the pharmacist who is working on that day in control room.

Who is responsible to manage the spillage and what is the first thing that needs to be done?

a)

Pharmacist Assistant.

Report to Management.

b)

Pharmacist.

Limit spill with absorbent towels dampened with DECON 90

c)

Pharmacist Assistant.

Limit spill with absorbent towel

d)

Pharmacist.

Put a warning sign to isolate spillage area

18.

You are Pharmacist who is working the on-call shift and received a call from 5PA, asking you on how to wear PPE. Which one of the following is the correct order of wearing PPE while handling cytotoxic spillage?

a)

Mask

Gloves

Gown

Gloves (2nd)

Goggles

Booties

b)

Gloves

Gown

Gloves (2nd)

Mask

Goggles

Booties

c)

Mask

Gloves

Gown

Gloves (2nd)

Booties

Goggles

d)

Gloves

Gown

Mask

Gloves (2nd)

Goggles

Booties

19.

ALL statements below are WRONG about of cytotoxic spill kit, EXCEPT :

a)

If the kit is used or the seal is broken, it must be returned to the pharmacy within 72 hours

post incidence.

b)

Sterile and Non- Sterile gloves are the items included in the spill kit

c)

Powder spillage requires the use of absorbent towel dampened with Decon 90 + Alcohol 20%.

d)

All used and unused items need to be returned to the pharmacy within the same day of incidence.

e)

Unused spill kits need to be re-serviced by 3 months times from preparation date

20.

What are the advantages of portable infusion devices (baxter bottle)?

a)

Promoting patient mobility

b)

No need for hospitalization

c)

To reduce toxicity in certain drugs

d)

All of the above

21.

The following regimens use baxter bottle for 5-Fluorouracil EXCEPT:

a)

FOLFOX

b)

FEC

c)

FOLFIRI

22.

The following infusion pumps are currently available in SC EXCEPT:

a)

Baxter Multi-rate bottle (2,3 or 5mL/hr)

b)

Baxter Fixed-rate bottle (2.5mL/hr)

c)

Bbraun Easypump (2mL/hr)

23.

TPN is a privision of nutrients administered intravenously to:

a)

Achieve catabolism

b)

Increase glucose intake

c)

Allow patient to eat quicker

d)

Achieve anabolism

24.

What energy component makes up the majority of TPN solution? 

a)

Lipid

b)

Vitamins

c)

Dextrose

d)

Amino acids

25.

Which of the following electrolytes should NOT be added together? 

a)

sodium & phosphate

b)

calcium & potassium

c)

magnesium & sodium 

d)

calcium & phosphate 

26.

Which one of the following statements is TRUE about the dangers of cytotoxics?

a)

Long term background exposure to multiple cytotoxic drugs is more of a concern than single event exposure to a single drug

b)

Cytotoxic drugs are harmless in small quantities

c)

We are protected from cytotoxic exposure as long as we just wear PPE

d)

It is a scam perpetuated by PPE manufacturers and the medical-industrial complex

27.

According to the Hierarchy of Controls, which of the following is the LEAST effective measure to reduce cytotoxic exposure?

a)

Standard Operating Procedure (SOP)

b)

Biosafety Cabinet

c)

Personal Protective Equipment (PPE)

d)

Designated area to store cytotoxic drugs, away from other drugs

28.

Which of the following places are you likely to find traces of cytotoxic drugs?

i) Furniture and surfaces in areas immediately outside Sterile Complex

ii) Sterile Complex changing room

iii) Patient infusion area at Oncology Daycare

iv) Cytotoxic drug storage area in pharmacy store

a)

i, iii, iv

b)

ii, iii, iv

c)

i, ii, iii

d)

All of the above