Font size
WorksheetsMirza Final exam
Total questions: 45
Worksheet time: 26mins
The most common IV diluents include
Saline (0.9% NaCl, NS)
5% D5W
Bacteriostatic water
Lactated Ringers
Which of the following are excipients in phenytoin?
Propylene glycol
Ethanol
Sodium Hydroxide (pH 10-12.3)
Water for Injections
Phenytoin is incompatible with
Dextrose
Dextrose-containing solutions
Other drug solutions..
NaCl
Attenuated (live), inactivated, subunit, toxoid, conjugate, DNA/RNA, recombinant vector are all examples of
Diseases
Incompatible injections
Vaccines
Which of the following are disadvantages of attenuated vaccines?
An attenuated microbe in the vaccine could revert to a virulent form and cause disease
Can't be given to people who have damaged or weakened immune systems
Pregnancy can't be attempted until 4 weeks after receiving live vaccine
Produces neurological disorders that have been directly linked to the live vaccine
Which vaccine is intended to build an immunity against the toxins, but not necessarily the bacteria that produce the toxins?
Conjugate
Subunit
Toxoids
Attenuated
Which of the following are advantages of RNA vaccines?
Shorter manufacturing times
Longer manufacturing times to ensure accuracy
No risk to causing disease in person getting vaccine
Mild to moderate risk of causing disease in person getting vaccine
What are the possible routes for vaccine administration?
Oral
Injections(IM,SQ,ID, IV)
Nasal
Rectal
Oral administration of vaccines
Are usually in liquid form
Have been engineered using foods, such as tomatoes
Are only available in capsule form
Have been engineered using eggs and need to be used with caution in pts with allergies
Aluminum gels or salts of aluminum are the most common adjuvants to be used that are FDA approved
True
False
Aluminum is an organic salt tat binds to proteins and causes them to precipitate
False
True
It is proven that vaccines cause autism
True
False
Where should most vaccines be stored?
In a 'Drug Only' Fridge
Freezer
At room Temperature
In the breakroom fridge, next to last weeks pizza
A biosimilar is the _____version of biologics
Fancy
Generic
Brand
Which of the following pertain to Genetic Engineering?
It is the process of direct manipulation of an organism's genome using biotechnology
Aims to alter cell's ability to produce proteins and thus add one or more new traits that aren't already found in that organism
Key techniques include rDNA and Monoclonal antibodies
rDNA utilizes human cells to manufacture proteins identical to those produced in human cells
true
false
Erbitux (Cetuximab) is used for
Treatment of colon cancer
Treatment of head cancer
Treatment of neck cancer
Treatment of prostate cancer
Which of the following apply to monoclonal antibodies (mAb)
They are lab-produced copies of a specific protein(antibody)
Produced entirely within the cells of higher animals, including the patient
Can be designed specifically to only target a certain antigen
Are often difficult to manipulate and control
Which of the following can be used as suspending vehicles?
Sterile water
Saline
Growth medium
gelatin
Which of the following can be used as stabilizers?
albumin
gelatin
phenol
monosodium glutamate
Which of the following can be used as a preservative in vaccines?
thermerosal
albumin
saline
sterile water
Formaldehyde is used as a ________and _______in vaccines
inactivator
detoxifier
pH stabilizer
preservative
US antibiotic vaccine all contain small-moderate amounts of penicillin
False
True
In vaccines, adjuvants are used as
suspending agents
stabilizers
enhancers
preservatives
Egg protein is used in which vaccines?
Influenza
Zoster
yellow fever
Pneumonia
Co-administration of tetracyclines with antacids containing Ca2+ will result in an increased absorption of the tetracycline
True
False
Acidic drugs have a tendency to be reabsorbed from a basic urine
True
False
Which of the following describes a strategy to prevent in vivo drug precipitation
By using glass infusion sets
By setting a slow infusion rate
By visually inspecting the IV solutions before their administration
What is the potential impact of a drug adsorption by plastics?
Increased drug concentration in the formulation
Decreased drug concentration in the formulation
Enhanced bioavailability of the drug
Enhanced therapeutic effect of the drug
When dispensing tetracycline (a chelate-forming drug) to a patient, a pharmacist should advise a patient to take the antibiotic with_____
A glass of milk
A glass of water
A Mg containing antacid
Mg containing multivitamins
What is the most common mechanism of incompatibility of dextrose solutions with the IV solutions of phenytoin?
In vivo pH alteration
Chelate formation between dextrose and onse of the excipients
Specific interactions between dextrose and propylene glycol
The process by which plasticizers are extracted by a liquid formulation is known as
Precipitation
Leaching
Adsorption
Evaporation
Chelators are beneficial in the treatment of heavy metals poisoning
True
False
Which of these is false?
Vaccines can't be administered orally
Vaccines are administered to establish immunity against a particular pathogen
A vaccine is a suspension of live or killed microorganisms or their fractions
Biologics are medical products made from a variety of natural choices
Concerning adjuvants, which of the following statements is false
Alum is a biological molecule
Alum causes protein precipitation
Adjuvants enhance the immune response to the vaccine
Aluminum salts are the most commonly used adjuvants
Erbitux (Cetuximab) is indicated for treatment of colon cancer and head cancer and is an example of _____
Novel drug delivery systems
Therapeutic monoclonal antibodies
Radiopharmaceuticals
Liposome-based formulation
rDNA
Regarding genetic engineering, which of the following is false
Bacterial cell are typically utilized for the production of mAB-based therapeutics
Insulin was one of the first rDNA commercial products
mAB and rDNA are key genetic engineering techniques
This process of direct manipulation of an organism's genome using biotechnology
Which of the following vaccines is intended to build immunity agaisnt the toxins but not necessarily the bacteria that produce the toxins
Toxoid vaccines
Subunit vaccines
Inactivated vacciens
Conjugate vaccines
Attenuated vaccines
Which type of vaccines has a potential to revert to a virulent form and cause actual disease
DNA vacciens
Subunit vaccines
Toxoid vaccines
Attenuated vaccines
Formaldehyde is an additive that is commonly used in inactivated vaccine formulation
True
False
Biosimilars are generic versions of biologics
True
False
RNA vaccines impose no risk of causing disease in a vaccinated person
True
False
There is a direct proof showing the association between vaccines and autism
True
False
Which of the following is the most typical storage requirement for vaccines
Room temperature
Controlled room temp
Keep refrigerated
Keep frozen
A multidose-vial influenza vaccine is labeled to contain themesoral. What is the function of thimesoral in the vaccine formulation?
Active component
Adjuvant
Vehicle
Preservative
