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Pharmaceutical Organic chemistry-II

Total questions: 10

Worksheet time: 8mins

Name
Class
Date
1.

Identify most deactivating meta directing group

a)

Amine

b)

Phenyl

c)

Alkoxy

d)

Nitro

2.

Electrophile in Friedel Craft’s Acylation is

a)

RCO+

b)

RCO-

c)

R+

d)

R-

3.

Identify the regent to convert amines into amides

a)

RX

b)

Acetic acid

c)

Sulphonyl chloride

d)

Benzoyl chloride

4.

Benzoic acid can be converted to m-nitrobenzoic acid by

a)

Nitrous acid

b)

Sulphuric acid

c)

Nitric acid

d)

Nitric acid +Sulphuric acid

5.

Iodination of fatty acids can be done by

a)

Potassium hydroxide

b)

Potassium permaganate

c)

Iodine

d)

IBr

6.

Friedel crafts alkylation in naphthalene takes place at C-2 position due to

a)

Formation of stable resonating structure

b)

Stable hybrid structure

c)

Less kinetic energy

d)

No hindrance effects

7.

Naphthalene on nitration results in to

a)

2- Nitro naphthalene

b)

1- Nitro naphthalene

c)

4- Nitro naphthalene

d)

3- Nitro naphthalene

8.

Starting material for synthesis of naphthalene by Howarth method’s is

a)

Benzene

b)

Toluene

c)

Aniline

d)

Nitrobenzene

9.

The cyclopropane is basically

a)

Planar in nature

b)

Non planar in nature

c)

Axial in plane

d)

Perpendicular to plane

10.

Addition of HBr to 1,1-dimethylcyclopropane gives

a)

2-Bromo butane

b)

2-Bromo-2-methyl butane

c)

3-Bromo butane

d)

4-Bromobutane