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Topic 5 Cell signalling

Total questions: 10

Worksheet time: 3mins

Name
Class
Date
1.

In response to a signal begin received a cell may ________.

a)

Grow and divide

b)

Survive

c)

Die

d)

All of the above

2.

Signalling from local mediator cell to targets in close proximity is an example of which kind of signalling?

a)

Endocrine

b)

Paracrine

c)

Neuronal

d)

Contact dependent

3.

The speed of a response to an extracellular signal depends apon.....

a)

The mechanism of signal delivery

b)

Whether transcription is required

c)

Whether protein function is altered

d)

All of the above

4.

In the signal transduction pathway the signal is passed though the cytoplasm via....

a)

Extracellular signalling molecules

b)

Effector proteins

c)

Receptor proteins

d)

Intracellular signalling molecules

5.

GTP proteins switch between active state (GDP bound) and inactive state (GTP bound)

a)

TRUE

b)

FALSE

6.

Cyclic AMP is synthesised by adenyl cyclase and degraded by ......

a)

Phospholipase C

b)

PKA

c)

cyclic AMP phosphodiesterase

d)

cyclic AMP phospholipase C

7.

RTKs are an example of enzyme coupled receptor but what does it stand for?

a)

Retinol transfer kinase

b)

Receptor tyrosine kinase

c)

Receptor threonine kinase

d)

Receptor transferase kinase

8.

During PI3-AKT pathway, activated AKT promotes what?

a)

Cell survival

b)

Cell death

c)

Cell differentiation

9.

Different signals originating from the plasma membrane can be integrated by cross talk between different signalling pathways inside the cell.

a)

TRUE

b)

FALSE

10.

Signalling molecules fall into 2 classes based on what?

a)

Size and charge

b)

Size only

c)

Charge only

d)

Chain length