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Unit 7 Mutations

Total questions: 25

Worksheet time: 32mins

Name
Class
Date
1.

What type of mutation is shown for #1

a)

Insertion

b)

Deletion

c)

Substitution

d)

Inversion

2.

What type of mutation is shown for #2

a)

Insertion

b)

Deletion

c)

Substitution

d)

Duplication

3.

What type of mutation is shown for #3

a)

Insertion

b)

Deletion

c)

Substitution

d)

Translocation

4.

What type of mutation is shown for #4

a)

Insertion

b)

Deletion

c)

Substitution

d)

Translocation

5.

(a)   mutation is when one letter or group of letters is swapped out for another letter or group of letters.

6.

(a)   mutation are when one letter or group of letters (codon) are completely removed from the DNA/RNA sequence.

7.

(a)   mutations are when a letter or group of letters are added into the middle of the DNA/RNA sequence, extra letters occur and cause a FRAMESHIFT usually.

8.

(a)   mutations are when a letter or group of letters are DOUBLED/REPEATED when they should not be.

9.

(a)   mutation is when one letter or group of letters moves and is placed into a whole different location than they should be in.

10.

Type of mutation that changes the DNA/mRNA sequence, but the protein that is made is the exact same as how it should be, and no effect/issues are shown.

a)

Frameshift

b)

Silent

c)

Nonsense

d)

Missense

11.

If the original sequence is ATG CAT, but the mutation sequence is AGG CAT, what type of mutation is this?

a)

Translocation

b)

Deletion

c)

Substitution

d)

Insertion

12.

An insertion often causes a __________ mutation, causing the mRNA to be read incorrectly, and the Amino acid sequence changes.

a)

Nonsense

b)

Missense

c)

Silent

d)

Frameshift

13.

Mutations have an effect on the body when the (a)   acid sequence is changes, causing a nonfunctioning protein to be made (shape change = wrong/no function).

14.

For proteins, a change in the amino acid sequence leads to a change in the _____ of the protein, which can make it nonfunctional (not working), protein folds wrong.

a)

Shape

b)

Color

c)

Amount

15.

Why does the mutation that causes sickle cell anemia have an effect on the red blood cells? (What job does it affect?).

4 lines
16.

Mutations can effect what proteins the (a)   makes (blank is the organelle that reads mRNA to produce polypeptides/proteins).

17.

Once proteins are produced, they need to be (a)   into their proper shape to match their function/job. This doesn't happen if the amino acid sequence is messed up in anyway.

18.

A nonsense mutations causes an incomplete protein to be made, because the mRNA tells the ribosome to (a)   building the protein and end translation. (HINT: what type of codon ENDS translation)

19.

If the amino acid sequence of a protein changes, the job will not be performed. This protein is now called a/an ___ protein

a)

Incomplete

b)

Duplicated

c)

Nonfunctioning

d)

Shortened

20.

AUG on mRNA means that tRNA will bring over the amino acid Methionine (Met), which is the ______________ codon. (HINT: This BEGINS TRANSLATION -> AKA Protein Synthesis)

a)

Start

b)

Stop

c)

End

d)

Anti

21.

Write out an example of a deletion mutation using the original DNA below:

22.

Write out an example of a substitution mutation using the original DNA below:

23.

Write out an example of an insertion mutation using the original DNA below:

24.

Write out an example of an inversion mutation using the original DNA below:

25.

Does a silent mutation have an effect an organism? Why or why not?

4 lines