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Lipid & lipoprotein analysis IP class

Total questions: 11

Worksheet time: 21mins

Name
Class
Date
1.
The characteristic that all lipids have in common is----
a)
made of lots of double bonds
b)
acidic when mixed with water
c)
no high energy content
d)
do not dissolve in water
2.

Monomers of Lipids include

a)

amino acids

b)

monosaccharides

c)

nucleotides

d)

glycerol and fatty acids

3.

Which of the following is a main function of a lipid?

a)

source of quick energy

b)

stores energy, insulates us, and makes up the cell membrane

c)

transport substances in and out of the cell

d)

stores genetic information

4.

Lipoproteins that contain mostly lipids are ____ dense than those containing mostly proteins.

a)

less

b)

more

c)

equally

5.

Which lipoprotein contains the highest percentage of protein?

a)

chylomicrons

b)

VLDLs

c)

LDLs

d)

HDLs

6.

The scavenger pathway involving HDLs seeks to remove excess ___ from the bloodstream.

a)

cholesterol

b)

LDLs

c)

VLDLs

d)

chylomicrons

e)

plaques

7.

Absorbed lipids will not go through the liver if they are being transported via

a)

chylomicrons

b)

VLDLs

c)

LDLs

d)

HDLs

8.

Affects lipid profiles (choose all possible answers)

a)

Total Cholesterol

b)

LDL-c

c)

HDL-c

d)

Triglyceride

9.

Which of the following statements accurately describes the basic principle of the enzymatic colorimetric method used to measure serum triglycerides in clinical chemistry laboratories?

a)

This method directly measures the absorbance of triglycerides at a specific wavelength after precipitation.

b)

This measurement involves the breakdown of triglycerides by lipase followed by the quantification of the released glycerol.

c)

This method requires ultracentrifugation to separate lipoprotein fractions before measurements can be made.

d)

This method relies on an oxidation reaction catalyzed by cholesterol oxidase to produce a colored substance.

e)

The measurement results represent the triglyceride levels found in the VLDL and chylomicron fractions.

10.

In the calculation of LDL-C using the Friedewald equation, which of the following conditions makes the equation inaccurate and requires direct measurement of LDL-C? (Difficulty Level: Medium)

a)

Total Cholesterol below 200 mg/dL

b)

HDL-C below 40 mg/dL

c)

Triglycerides above 400 mg/dL

d)

Fasting time less than 10 hours

e)

Total Cholesterol to HDL-C ratio greater than 5

11.

A patient starts Statin therapy. Which expected change in the follow-up lipid panel most indicates the therapeutic efficacy of the drug in reducing atherosclerotic cardiovascular disease (ASCVD) risk? (Difficulty Level: Medium)

a)

Significant increase in HDL-C levels

b)

Significant decrease in VLDL levels

c)

Significant decrease in LDL-C levels

d)

Normalization of triglyceride levels

e)

Decrease in the ratio of LDL-c to HDL-c