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Regulation of Gene Expression

Total questions: 21

Worksheet time: 11mins

Name
Class
Date
1.

Observe the pic then answer the question that follows.


Question: Gene regulation is the process that is used to:

a)

help make sugars for cells in plants.

b)

turning genes on and off.

c)

make glycosomes in cells.

d)

Not sure. Code RED need help.

2.

When gene expression occurs

a)

A gene is mutated with either an insertion or deletion

b)

The gene is removed from the genotype in that cell

c)

The gene is passed on to the daughter cells during mitosis

d)

The gene is activated and used in protein synthesis

3.

Which reason explains why nerve cells function differently than muscle cells?

a)

In nerve cells all the genes are expressed.

b)

In muscle cells all the genes are expressed.

c)

In both kinds of cells the same genes are expressed.

d)

In both kinds of cells different genes are expressed.

4.
Most gene regulation happens at which step along the way?
a)
translation
b)
transcription
c)
signal transduction
d)
DNA replication
5.

An operon is

a)

a genetic on/off switch in prokaryotes

b)

a genetic on/off switch in eukaryotes

c)

a group of related genes and the associated gene switches in prokaryotes

d)

a group of related genes and the associated gene switches in eukaryotes

6.

In the trp operon, __ acts as a __ and helps the repressor bind to the operator.

a)

tryptophan, corepressor

b)

tryptophan, inducer

c)

lactose, corepressor

d)

lactose, inducer

7.

Where does the RNA Polymerase bind to for the initiation of

a)

Regulator

b)

Structural genes

c)

Operator

d)

Promotor

8.

RNA polymerase needs --- to initiate transcription.

a)

holoenzymes

b)

transcriptional factors

c)

histones

d)

microRNA

9.

which is correct?

a)

heterochromatin-dense, no transcription;

euchromatin- not dense, transcription

b)

euchromatin-dense, no transcription;

heterochromatin- not dense, transcription

c)

histone acetylation- increase transcription; histone methylation (and DNA methylation)- decrease transcription

d)

histone methylation- increase transcription; histone acetylation- decrease transcription

10.

True or False: All of your body cells contain the same genes.

a)

True

b)

False

11.

What is the final step of regulation of gene expression?

a)

Protein folding

b)

Protein breakdown

c)

Regulation of translation

d)

Gene splicing

12.

Which of the following would most likely be an "on," or highly expressed, gene?

a)

A gene in heterochromatin

b)

A gene with a short poly-A tail

c)

A gene with alot of introns

d)

A gene with a strong promoter

13.

Heterochromatin

a)

Usually has methylated DNA

b)

Usually does not have acetylated histones

c)

contains genes that are not expressed

d)

All of these are true

14.

Prokaryotes regulate gene expression primarily

a)

in order to maintain homeostasis

b)

in response to changing environmental conditions

c)

during development as cells specialize

d)

Prokaryotes do not regulate gene expression. All genes are always on.

15.

One way to regulate the expression of a gene is to control the formation of mRNA. This is called ___ control.

a)

transcriptional

b)

translational

c)

post-transcriptional

d)

post-translational

16.

In order for a gene to be expressed, ___ must bind to the gene's ___, a specific sequence of nucleotides at one end of the gene, thus initiating transcription.

a)

DNA polymerase, promotor

b)

DNA polymerase, operator

c)

RNA polymerase, promotor

d)

RNA polymerase, operator

17.

Eukaryotes need to regulate their genes

a)

during cell specialization that occurs during development

b)

in order to maintain homeostasis

c)

both a and b

d)

neither a or b

18.

___ are DNA sequences which are often located far from the genes they regulate in eukaryotes where transcription activators can bind.

a)

histones

b)

promotors

c)

enhancers

19.

Which of the following help to turn genes on so that they are expressed (transcribed and translated)?

a)

a high level of condensation (coiling around histones)

b)

histone acetylation

c)

DNA methylation

d)

histone methylation

20.

Which of the following are types of post-transcriptional control of genes in eukaryotes?

a)

alternative RNA splicing or processing

b)

gene silencing through RNA interference

c)

destruction of ubiquitin tagged proteins

d)

all of the above

21.

Alternative RNA splicing involves

a)

removing introns and splicing the same exons together

b)

removing exons and splicing the same introns together

c)

removing introns and splicing different exons together

d)

removing exons and splicing different introns together