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Immune System and Immune System disorders Quiz

Total questions: 42

Worksheet time: 21mins

Name
Class
Date
1.

Which of the following cells is an antigen presenting cell? Select all that apply

a)

Dendritic Cell

b)

Macrophage

c)

Plasma cell

d)

Natural Killer Cell

e)

T helper Cell

2.

These are markers on any pathogen that your immune system recognizes as "foreign" and creates memory cells to combat.

a)
antigens
b)
antibodies
c)
killer t-cells
d)
B-cells
3.
Y shaped proteins that may mark pathogens for destruction are
a)
antigens
b)
T cells
c)
antibodies
d)
neutrophils
4.

When Memory B cells see a pathogen they recognize, they quickly "mature" into these cells that produce antibodies:

a)

Naive B Cells

b)

Plasma Cells

c)

Phagocytes

d)

Mast Cells

5.

Skin, mucous membranes, and phagocytes/ macrophages all parts of the:

a)

Innate Immune System

b)

Acquired Immune System

c)

Secondary Response

d)

Antigen Producing Cells

6.

These cells find and kill your own cells that are infected with pathogens:

a)

Cytotoxic T Cells

b)

Memory B Cells

c)

T Helper Cells

d)

Antibodies

7.

Antigen Presenting Cells (APCs):

a)

Destroy any "invader" they encounter and present part of it to your immune system

b)

Recognize antigens presented to them and become Memory B cells

c)

Destroy your own cells that are infected w/ pathogens

d)

Lie, cheat, and steal their way to success

8.

T cells mature in the

a)

thyroid gland

b)

spleen

c)

thymus

d)

plasma cells

9.

Both T cells & B cells are created in the

a)

bone marrow

b)

pancreas

c)

thymus

d)

spleen

10.

Barrier defenses

a)

can physically block pathogens from entering the body.

b)

can chemically destroy pathogens before they can infect the body.

c)

include nonpathogenic bacteria that outcompete pathogens.

d)

All of the other answers are correct

11.

Which of the following statements apply to the innate immune system?

a)

It targets a specific pathogen.

b)

It takes several days to work.

c)

Consists of B and T cells.

d)

It includes fever and inflammation.

12.

An antigen is ______, whereas an antibody is_______.

a)

a foreign substance to which lymphocytes respond; a protein that binds to antigens to eliminate them

b)

a protein that is produced by lymph nodes in response to bacteria; a foreign protein that enters the body and causes an immune reaction

c)

a hapten molecule that is quite complicated in shape; an enzyme that is produced by the thymus gland to neutralize antigens

d)

produced by T-cells; produced by B-cells

13.

Which B cells remain in the body for decades, allowing for a much more rapid specific response upon reinfection?

a)

killer B cells

b)

memory B cells

c)

plasma cells

d)

macrophages

14.

Antibodies

a)

are all exactly identical.

b)

are produced by the innate immune system.

c)

are cells that "eat" pathogens.

d)

are highly specific to an antigen.

15.

Autoimmune diseases occur when immune cells

a)

are destroyed by viruses.

b)

are trained to recognize foreign antigens.

c)

attack body cells.

d)

consume pathogens.

16.

Bee stings cause an allergic reaction due to:

a)

Skin Contact

b)

Injection

c)

Ingestion

d)

Inhalation

17.

Shellfish cause an allergic reaction due to:

a)

Skin Contact

b)

Injection

c)

Ingestion

d)

Inhalation

18.

Phagocytes:

a)

deal with parasitic infections

b)

involved in allergic reactions

c)

eat and destroy pathogens

d)

deal with specific invaders

19.

Eosinophils:

a)

attack and destroy large eukaryotic pathogens like fungi and helminths

b)

are involved in inflammation and allergic reactions

c)

engulf and destroy bacterial pathogens

d)

activate T helper cells

e)

produce antibodies

20.

Basophils:

a)

deal with parasitic infections

b)

are involved in inflammation and allergic reactions

c)

engulf and destroy bacterial pathogens

d)

present antigens to activate T helper cells

e)

produce antibodies

21.

What is the specific region of the antigen that is recognized by receptors of B-cells and T-cells?

a)

Epitope

b)

Paratope

c)

Antigen-binding site

d)

Both A and B

22.

What are the requirements for a substance to be considered as highly immunogenic?

a)

The substance should be foreign

b)

The substance should be small

c)

The substance should be chemically complex

d)

The substance should be of high molecular weight

e)

The substance should be produced by the body

23.

What is the process in which antibodies bind to viruses and block the site used by viruses to enter the cells ?

a)

Opsonization

b)

Lysis

c)

Neutralization

d)

Phagocytosis

24.

What structure/s of the antibody form/s the antigen-binding site?

a)

Light variable region

b)

Light constatn region

c)

Heavy variable region

d)

Heavy constant region

25.

What structure of antibody is shown in number 1?

a)

Antigen-binding site (paratope)

b)

Fab region

c)

Fc region

d)

Light constant chain

26.

The immunoglobulin isotype shown in the figure is one of the antibody types that is produced when someone is first exposed to an antigen. Which isotype of antibody is it?

a)

IgA

b)

IgD

c)

IgM

d)

IgE

e)

IgG

27.

The immunoglobulin isotype shown is found on mucous membranes, saliva, and tears. Which isotype is this?

a)

IgE

b)

IgA

c)

IgD

d)

IgM

e)

IgG

28.

What characteristics make the adaptive immunity different from the innate immunity?

a)

Memory

b)

Reactivity

c)

Specificity

d)

Affinity

29.

What specific cells of the adaptive immunity secrete cytokines?

a)

Cytotoxic T-cells

b)

Phagocytes

c)

Helper T-cells

d)

Natural Killer cells

30.

What specific type of B-cells produce the antibodies?

a)

Mast Cells

b)

Plasma cells

c)

Phagocytes

d)

Eosinophils

31.

Which of the following provide defense against viral infections?

a)

Histamines

b)

Antibiotics

c)

Prostaglandins

d)

Interferons

32.

Which immunoglobulin isotype is most important for long-term immunity?

a)

IgA

b)

IgD

c)

IgM

d)

IgE

e)

IgG

33.

A/an _____ is an exaggerated immune response that results in rapid onset of inflammatory symptoms.

a)

graft rejection

b)

antibody mediated hypersensitivity

c)

allergy

d)

autoimmune disorder

34.

These cells release granules that contain inflammatory mediators when the IgE antibodies bound to their membrane encounter their specific antigen.

a)

Neutrophils

b)

Mast cells

c)

Plasma cells

d)

NK cells

e)

Dendritic cells

35.

What blood type would an individual with the genotype ii have?

a)

Type A

b)

Type B

c)

Type O

d)

Type AB

36.

What blood type would has B antigens on red blood cells?

a)

Type A

b)

Type B

c)

Type O

d)

Type AB

37.

What blood type produces no antibodies against A or B antigens?

a)

Type A

b)

Type B

c)

Type O

d)

Type AB

38.

What blood type is considered a universal donor?

a)

Type A

b)

Type B

c)

Type O

d)

Type AB

39.

What blood type is considered a universal receiver?

a)

Type A

b)

Type B

c)

Type O

d)

Type AB

40.

Type I diabetes is caused by an autoimmune reaction that results in the destruction of _____ which produce insulin.

a)

thyroid cells

b)

beta cells

c)

alpha cells

d)

CD4+ cells

41.

This disease is the result of an autoimmune reaction that results in the destruction of the myelin sheath around the axons of motor neurons.

a)

Myasthenia gravis

b)

Lupus

c)

Graves Disease

d)

Multiple sclerosis

e)

Hashimoto's

42.

This primary immunodeficiency results in the loss of both B cell and T cell functions

a)

AIDS

b)

SCID

c)

Immunosuppressor drugs

d)

Cancer