WorksheetsBIO342-- Spina Bifida
Total questions: 8
Worksheet time: 80secs
Name
Class
Date
1.
What pathway is affected regarding Spina Bifida?
a)
Shh
b)
Wnt
c)
FGF
d)
BMP4
2.
What is the most common type of Spina Bifida?
a)
Myelomenigocele
b)
Occulta
c)
Meningocele
3.
BMP4 induces an epidermal fate in the dorsal ectoderm
a)
True
b)
False
4.
Lack of what protein causes BMP4 to be overexpressed?
a)
Gli3
b)
Noggin
c)
FGF
d)
Shh
5.
Which kind of mutation in VANGL1 was associated with Spina Bifida?
a)
Missense
b)
Nonsense
c)
Substitution
d)
Deletion
6.
Mouse embryos lacking Noggin showed elevated FGFs
a)
True
b)
False
7.
The dorsolateral hinge points (DLHPs) are
a)
Present during gastrulation
b)
Part of the neural folds
c)
Induced by Shh
d)
Precursors to the neural folds
8.
Which is a key characteristic of Spina Bifida?
a)
Loss of sensation in the upper half of the body
b)
Type I Chiari malformation
c)
Loss of cerebrospinal fluid
d)
Weakness or paralysis of the legs
100 %
