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Molecular Basis of Inheritance (13)

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

In his transformation experiments, which of the following results did Griffith observe?

a)

Mutant mice were resistant to bacterial infections.

b)

Mixing a heat-killed pathogenic strain of bacteria with a living nonpathogenic strain can convert some of the living cells into the pathogenic form

c)

Mixing a heat-killed nonpathogenic strain of bacteria with a living pathogenic strain makes the pathogenic strain nonpathogenic

d)

.

Infecting mice with nonpathogenic strains of bacteria makes them resistant to pathogenic strains.

2.

Which of the following statements most accurately describes transformation in bacteria?

a)

Transformation is the creation of a strand of DNA from an RNA molecule.

b)

Transformation is the creation of a strand of RNA from a DNA molecule.

c)

Transformation is the infection of cells by a phage DNA molecule

d)

D.

Transformation is the assimilation of external DNA into a cell.

3.

In trying to determine whether DNA or protein was the genetic material, Hershey and Chase made use of which of the following facts about these two types of molecules?

a)

DNA contains sulfur, whereas protein does not.

b)

B.

DNA contains phosphorus, whereas protein does not

c)

DNA contains nitrogen, whereas protein does not

d)

DNA contains purines, whereas protein includes pyrimidines

4.

Which of the following statements correctly describes one of Chargaff's rules regarding DNA?

a)

The percentages of adenine and cytosine are roughly equal, as are the percentages of guanine and thymine in the DNA of a given species

b)

DNA has a double helical structure

c)

DNA base composition does not vary between species

d)

The percentages of adenine and thymine are roughly equal, as are the percentages of guanine and cytosine in the DNA of a given species

5.

Which of the following characteristics of the structure of DNA allows it to carry a large amount of hereditary information?

a)

the sequence of bases

b)

phosphate-sugar backbones

c)

complementary pairing of bases

d)

different five-carbon sugars

6.

In an analysis of the nucleotide composition of DNA, which of the following will be found in a given DNA molecule?

a)

A.

A = C

b)

A = G and C = T

c)

C.

A + C = G + T

d)

G + C = T + A

7.

What is meant by the description "antiparallel" regarding the two strands of nucleic acids that make up DNA?

a)

The twisting nature of DNA creates nonparallel strands.

b)

The 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other strand.

c)

Base pairings create unequal spacing between the two DNA strands.

d)

One strand contains only purines and the other contains only pyrimidines.

8.

Which of the following statements describes one difference between DNA replication in prokaryotes and DNA replication in eukaryotes?

a)

.

Prokaryotic chromosomes have histones, whereas eukaryotic chromosomes do not

b)

Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many.

c)

The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes.

d)

Prokaryotes produce Okazaki fragments during DNA replication, but eukaryotes do not.

9.

Which of the following statements correctly describes one characteristic of DNA replication in eukaryotes?

a)

Prokaryotic chromosomes have histones, whereas eukaryotic chromosomes do not

b)

Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many.

c)

The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes.

d)

Prokaryotes produce Okazaki fragments during DNA replication, but eukaryotes do not.

10.

Which of the following statements correctly describes how the leading and the lagging strands of DNA formed during DNA replication differ?

a)

The leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction.

b)

The leading strand is synthesized by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5' end.

c)

The lagging strand is synthesized continuously, whereas the leading strand is synthesized in short fragments that are ultimately stitched togethe

d)

The leading strand is synthesized at twice the rate of the lagging strand