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Novomix Q Bank

Total questions: 22

Worksheet time: 16mins

Name
Class
Date
1.

Bebaker et al was published in?

a)

2009

b)

2007

c)

2010

d)

2012

2.

What is the study design of the BeBaker et al?

a)

26 week, open labelled, multicenter, randomized (2:1)

b)

24-week, open labelled, multi-centre, randomized (1:1)

c)

26-week, double blind, multicenter, randomized (2:1)

d)

24 week, double blind, multicenter, randomized (2:1)

3.

In Bebaker et al. after week 14 subjects with what HbA1C were intensified to twice daily NovoMix regimen?

a)

>8.5%

b)

>8.0%

c)

>7.0%

d)

>9.0%

4.

In Bebaker et al. mean reduction with Novomix (OD) in comparison to OADs was

a)

1.34% vs 0.67%

b)

1.24% vs 0.67%

c)

1.7% vs 0.8%

d)

1.5% vs 0.9%

5.

In Bebaker et al. aim is to evaluate the efficacy and safety of adding biphasic insulin aspart 30 (BIAsp30; NovoMix 30) to existing oral antidiabetic agents (OADs) vs. optimizing OADs in a subgroup of Western Pacific patients with type 2 diabetes inadequately controlled on oral monotherapy or oral combination therapy.

a)

True

b)

False

6.

Bebakar et al is a 24-week, multi-centre, open-labelled, randomized, two-arm parallel trial consisted of a 2-week screening period, followed by 24 weeks of treatment.

a)

True

b)

False

7.

In Bebaker et al. Hypoglycaemic episodes were reported in 53% of the patients in BIAsp30 (o.d. and b.i.d. pooled) and 30% of the patients in OAD-only group.

a)

True

b)

False

8.

In Bebaker et al. Subjects randomized to the OAD-only arm (n ¼ 63) continued with their previous OAD treatment.

a)

False

b)

True

9.

In Bebaker et al. all episodes were minor or symptomatic, except for one in each treatment group, which was minor.

a)

True

b)

False

10.

In Bebaker et al. an attempt to reach treatment goals, the dose was optimized (but OAD changed) in accordance to local treatment practice and labelling.

a)

True

b)

False

11.

Sit2Mix was published in which Journal

a)

Diabetes and Obesity

b)

Primary Care Diabetes

c)

Diabetes and Clinical Practice

d)

Diabetes and Metabolism

12.

In Linjawi et al. BIAsp30 added with Sitagliptin + Metformin once or twice daily in T2D patients.

a)

True

b)

False

13.

In Linjawi et al. BIAsp30 was given twice daily without Sitagliptin + metformin

a)

True

b)

False

14.

LINJAWI was a randomized, open Label, three arm parallel group local trial

a)

True

b)

False

15.

Linjawi was published in 2015

a)

False

b)

True

16.

Sit2Mix Aim is to investigate efficacy and tolerability of intensifying diabetes treatment

a)

True

b)

False

17.

linjawi Trial is in insulin naïve patients with duration of

a)

24 week

b)

26 week

c)

12 week

d)

28 week

18.

What was the baseline HBA1c (%) in Sit2Mix.

a)

9.1%

b)

8.4%

c)

7.5%

d)

10%

19.

In Linjawi et al. Observed final HBA1c values are with (BIAsp30 BID + Sit), (BIAsp30 QD + Sit), (BIAsp30 BID – Sit)

a)

6.9%, 7.2%, 7.0%

b)

6.9%, 7.2%, 7.1%

c)

7.1%, 7.2%, 6.9%

20.

In Linjawi et al. Confirmed Hypoglycaemia was lower with BIAsp30 QD + Sit vs BIAsp30 BID + Sit vs BIAsp30 BID.

a)

True

b)

False

21.

In which year Strojek et. All study has been published.

a

a)

2006

b)

2009

c)

2012

d)

2015

22.

In how many weeks Strojek et. All study was conducted.

a)

10 weeks

b)

30 weeks

c)

26 weeks

d)

28 weeks