is when the wound edges come together – like what happens when two wounds‟ margins are stitched or sutured together.

occurs when the wound edges are too far from one another – this can be consequence of significant tissue loss or if there‟s an object embedded in the wound that prevents the edges from coming together.

is when a wound is cleaned and purposefully left open due to a high likelihood of being contaminated by bacteria – like during a dog bite injury.

In primary intention, stem cells in the epidermis or uppermost layer of skin are brought close together and can regenerate the damage tissue near the surface of skin – leaving a minimal scar.

Since in the Secondary intention the stem cells in these wounds do not approximate, the wound is replaced primarily by connective tissue that grows from the base of the wounds upwards.

Give examples of healing by secondary intention

Healing of primary union is usually completed in ______ _____

Wound closure is performed with

What are the four important stages of wound healing

“Blood clotting”

1) Constriction of the blood vessel

2) Formation of a temporary “platelet plug."

3) Activation of the coagulation cascade.

- Starts at the onset of injury and is designed to stop any bleeding

Stage 1: hemostasis for small wound will take up to _____

Stage 1: hemostasis for Large wound will take up to _____

This stage is where the prevention of infection happens.

- happens once the bleeding has stopped (with the help of clot formation)

- body‟s key defense mechanism

Increased blood flow

Exudation of fluid

Increased blood flow, exudation of fluid, release inflammatory mediators

Stretching of pain receptors and nerves by inflammatory exudates, Chemical mediators

Pain, Disruption of tissue structure, fibroplasia and metaplasia

“Closing of wound”

Once the wound is already cleaned, it can now proceed to the rebuilding stage which can be broken down into three mini parts.

Stage 2: Inflammation may take up to _____ then go away

Stage 3: Proliferation may take up to _____

“Strengthening stage” This stage was also called, remodeling stage because new tissue that was built in the proliferative stage needs to build strength and flexibility.

How does this happen?

Water is reabsored so collagen fibers can lie closer together making it strong and flexible. Scarring occurs.

Stage 4: Maturation may take up to _____