A gene mutation that is comprised of insertion of three nucleotide is a non-frameshift mutation.

A mother who suffers a mitochondrial DNA disease will pass down the disease to his son with 100% probability.

Down syndrome is an aneuploidy disorder.

22q11.2 deletion syndrome occurs due to loss of chromosome 22.

Poorly differentiated neoplastic cells may become malignant tumors.

Cancer cells favor to undergo apoptosis.

Mutation in tumor suppressor gene can inhibit cancer cell growth.

Benign tumor does not require any medical intervention.

T1N0MX tumor is more severe than a T3N1M0 tumor.