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cell communication

Total questions: 20

Worksheet time: 12mins

Name
Class
Date
1.

(a)   signaling

2.

(a)   signaling

3.

(a)   signaling

4.

Type of signaling

a)

endocrine

b)

paracrine

c)

contact-dependent

d)

synaptic

5.

Second messenger

a)

G protein

b)

cAMP

c)

protein kinase A

d)

tyrosine kinase

6.

This is not second messenger

a)

cAMP

b)

cGMP

c)

Ca2+

d)

IP3

e)

adenylyl cyclase

7.

General term for a protein that binds a specific extracellular molecule (ligand) and initiates a response in the cell.

a)

hormone

b)

receptor

c)

adaptor

d)

second messenger

8.

Short-range cell–cell communication via secreted local mediators that act on adjacent cells.

a)

endocrine

b)

paracrine

c)

contact-dependent

d)

synaptic

9.

A signal relay chain involving multiple protein kinases, each of which is activated by phosphorylation and then phosphorylates the next protein kinase in the sequence.

a)

desensitization

b)

contact-dependent signaling

c)

kinase cascade

d)

inositol phospholipid signaling pathway

10.

Small molecule that is formed in the cytosol, or released into it, in response to an extracellular signal and that helps to relay the signal to the interior of the cell.

a)

hormone

b)

neurotransmitter

c)

second messenger

d)

receptor

11.

Molecule from outside the cell that communicates the behavior or actions of other cells in the environment and elicits an appropriate response.

a)

extracellular signal molecule

b)

receptor

c)

adaptor

d)

second messenger

12.

Enzyme that transfers the terminal phosphate group of ATP to a specific amino acid of a target protein.

a)

protein phosphatase

b)

cyclic AMP phosphodiesterase

c)

protein kinase

d)

phospholipase C

13.

Small signal molecule secreted by the presynaptic nerve cell at a chemical synapse to relay the signal to the postsynaptic cell.

a)

hormone

b)

neurotransmitter

c)

second messenger

d)

receptor

14.

Enzyme that phosphorylates target proteins in response to a rise in intracellular cyclic AMP.

a)

protein kinase C (PKC)

b)

cyclic-AMP-dependent protein kinase (PKA)

c)

cyclic AMP phosphodiesterase

d)

phospholipase C

15.

A Ca2+-dependent protein kinase that is activated by diacylglycerol.

a)

protein kinase C (PKC)

b)

cyclic-AMP-dependent protein kinase (PKA)

c)

cyclic AMP phosphodiesterase

d)

phospholipase C

16.

******************** signaling

a)

endocrine

b)

paracrine

c)

autocrine

d)

synaptic

17.

What is the importance of inositoltriphosphate (IP3)?

a)

activates adenylate cyclase

b)

activates protein kinase A

c)

activates protein kinase C

d)

binding  with Ca2+ channels of plasmolemma and endoplasmic reticulum translates them into an open state

18.

What cellular mechanism responds to its own signal of the cell (the cell produces a signaling molecule and at that time carries on its surface the receptors necessary for respond of the secreted ligand)?

a)

paracrine signaling

b)

autocrine signaling

c)

endocrine signaling

d)

synaptic signaling

19.

What type of secondary messengers is formed from a specialized membrane lipid inositolphospholipid by the enzyme phospholipase C?

a)

diacylglycerol (DAG) and inositol triphosphate (IP3)

b)

Ca2+ and cAMP

c)

Ca2+ and inositol triphosphate (IP3)

d)

cAMP and diacylglycerol (DAG)

20.

What is the importance of diacylglycerol (DAG)?

a)

activates adenylate cyclase

b)

activates protein kinase A

c)

activates protein kinase C

d)

binding  with Ca2+ channels of plasmolemma and endoplasmic reticulum translates them into an open state