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Basic methods for studying human heredity

Total questions: 13

Worksheet time: 7mins

Name
Class
Date
1.

What method of studying heredity used in the diagnosis of chromosomal diseases?

a)

genealogical

b)

population-statistics

c)

biochemical

d)

cytological

2.

  Why twin methods is used  for studying human heredity?

a)

to establish the hereditary nature of the trait

b)

to determine the type and variant of inheritance

c)

for the diagnosis of chromosomal abnormalities

d)

to assess the relative role of heredity and environment in the development of the trait

3.

  What is function of cytogenetic method?

a)

study of gene mutations and diagnosis of gene diseases

b)

study genome and chromosome mutations and diagnosis of chromosomal diseases

c)

to assess the correlative role of heredity and environment in the development of the trait

d)

establishing the hereditary nature of the trait

4.

What method is used in the diagnosis of hereditary metabolic defects?

a)

cytogenetic

b)

twins

c)

biochemical

d)

population-statistics

5.

What is the essence of biochemical method?

a)

the study of genetic patterns in both mono- and dizygotic twins

b)

the use of qualitative and quantitative tests system, which allows to catch the impaired content of metabolic products

c)

cultivation of human somatic cells on nutrient media

d)

modeling on animal the hereditary pathological signs of human

6.

What is the essence of cytogenetic method?

 

a)

to study the chromosome of a cell under a microscope

b)

to study cell organelles under the microscope

c)

to study molecular structure of cells

d)

to study the mechanism of cell division

7.

What is the population-statistic method?

a)

it is the study about features of the demographic indicator of the population in certain regions

b)

it is the study about a general statistics of the population

c)

it is the studying about features of distribution among the population on somatic and infectious diseases

d)

  it is the study about features of the distribution hereditary traits and genes controlling them in different groups of people

8.

Cytogenetic and genetic studies showed that each chromosome is differentiated into two types of different in color plots. Areas that weakly stained by nuclear dyes were identified:

a)

Euchromatin

b)

Heterochromatin

c)

Kinetochore

d)

Centromere

9.

If a trait is determined mostly by genetic factors, the percentage of concordance between the twins is much higher in monozygotic twins than in dizygotic ones. What is the percentage of blood group concordance in monozygotic twins?

a)

100%

b)

75%

c)

50%

d)

25%

10.

Healthy parents have got a fairhaired, blue-eyed girl. Irritability, anxiety, sleep and feeding disturbance developed in the first months of the infant’s life. Neurological examination revealed developmental lag. What method of genetic investigation should be used for the exact diagnosis?

a)

Genealogical

b)

Cytological

c)

Biochemical

d)

Population-statistical

11.

There are trisome, translocational and mosaic forms of Down’s syndrome. What method of human genetics can be applied to differentiate the said forms of Down’s syndrome?

a)

Genealogical

b)

Cytogenetical

c)

Biochemical

d)

Population-statistical

12.

How do you achieve the high mitotic activity of lymphoid cells in the cytogenetic research?

a)

by acting with a solution of colchicines

b)

by acting with phytohemagglutinin

c)

by acting with hypotonic solution

d)

by acting with a solution containing ethyl alchohol

13.

How do you achieve (during the cytogenetic method) the destruction of spindle division and stop cell division at the stage of metaphase?

a)

by acting with a solution of colchicines

b)

by acting with phytohemagglutinin

c)

by acting with hypotonic solution

d)

by acting with a solution containing ethyl alchohol