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WorksheetsDrugs for Bronchial Asthma, RA and Gout
Total questions: 15
Worksheet time: 4mins
Which of the following drugs is useful in asthma because it stabilizes mast cells?
Salbutamol
Cromolyn
Ipratropium
Theophylline
A 13-year-old boy with severe asthma has been treated for 6 months with good control of nocturnal wheezing. His parents now complain that he seems to be very fat around the face and shoulders, bruises easily, and has discolored streaks on his abdomen. Laboratory tests reveal moderate hyperglycemia. He has probably been receiving which of the following drugs?
ipratropium
prednisone
salmeterol
terbutaline
Which of the following is the drug of choice to reverse bronchoconstriction in an acute asthma attack?
Salbutamol
Aminophylline
Salmeterol
Ipratropium
The most prominent and dose related side effect of
salbutamol is:
Rise in blood pressure
Muscle tremor
Hyperglycaemia
Central nervous system stimulation
Select the fastest-acting inhaled bronchodilator:
Ipratropium bromide
Formoterol
Salbutamol
Salmeterol
Select the correct statement about salmeterol:
It is a long acting selective β2 agonist bronchodilator
It is a bronchodilator with anti-inflammatory
property
It is a β blocker that can be safely given to
asthmatics
It is an antihistaminic with mast cell stabilizing
property
Select the most appropriate drug for regular prophylactic therapy in a 10 year old child who suffers from exercise induced asthma:
Oral salbutamol
Oral theophylline
Inhaled sodium cromoglycate
Inhaled salmeterol
Select the drug that is neither bronchodilator nor anti-inflammatory, but has antihistaminic and mast cell stabilizing activity:
Sodium cromoglycate
Ketotifen
Beclomethasone
Montelukast
Leukotriene antagonists are used in bronchial asthma:
For terminating acute attacks
As monotherapy in place of β2 agonists
As nebulized powder in refractory cases
As adjuvants to β2 agonists for avoiding
corticosteroids
Choose the correct statement about theophylline:
Its use in asthma has declined because of
narrow safety margin
Its dose needs to be reduced in smokers
It acts by increasing the formation of cAMP
Its plasma halflife is longer in children compared
to that in adults
Identify the first line disease modifying antirheumatic drugs.
Anakinra
Hydroxychloroquine
Prednisolone
Methotrexate
A woman with RA planning pregnancy asks about medication safety. Which drug is contraindicated in pregnancy because of teratogenicity?
Hydroxychloroquine
Sulfasalazine
Methotrexate
Prednisone (low dose)
The selective COX-2 inhibitors have the following
advantage(s) over the nonselective NSAIDs:
They have more potent analgesic effects.
They are not likely to produce renal
complications
They are likely to be more effective in
rheumatoid arthritis
They are less likely to cause gastric ulcers
and their complications
A 55-year-old man presents with acute monoarticular pain of the first metatarsophalangeal joint starting 12 hours ago. Which of the following is first-line pharmacologic therapy for acute gout attack in a patient with no contraindications?
Allopurinol
Indomethacin
Probenecid
Febuxostat
Which adverse effect is most characteristically associated with chronic colchicine therapy?
Hepatotoxicity with elevated transaminases
Dose-related GI upset and diarrhea
Hypoglycemia
Agranulocytosis
