WorksheetsAllergic Response Quiz
Total questions: 10
Worksheet time: 6mins
Example of a deficiency in an inhibitor of the C1 complement system
Hereditary (autosomal dominant) angioedema
Acquired angioedema associated with lymphoma
Acquired angioedema associated with lymphosarcoma
Acquired angioedema associated with chronic lymphatic leukemia
All are examples of a deficiency in an inhibitor of the C1 complement system
Hypersensitivity reaction is independent of complement activation
Type I and IV
Type II and Type III
Type II and Type IV
Type I and III
A patient was undergoing a series of surgical procedures requiring general anesthetic. At the third procedure he suddenly became hypotensive with marked cardiac arrhythmia. In addition his breathing became difficult due to extensive bronchocorstriction and obstructive laryngeal edema. Despite the efforts of the surgical team the patient developed severe and permanent brain damage due to hypoxemia. It was subsequently discovered that the patient had developed IgG antibodies to the anesthetic gas and this had resulted in an anaphylactoid response to the anesthetic. What type of reaction caused this condition?
Type I
Type II
Type III
Type IV
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The ability of this organism to cause disease is related to it’s ability to infect, persist in, and replicate within macrophages. The lepromin skin test is used to determine what type of leprosy a person has. In this test, inactivated Mycobacterium leprae organisms are injected just beneath the skin. At the site of injection, a person with a positive test will develop an area of induration with erythema peaking around 48 hours after the injection. If this test measures a hypersensitivity reaction against the organism, what type of hypersensitivity reaction is it intended to detect?
Type I
Type II
Type III
Type IV
The principle difference between type II and type III hypersensitivity is
The class (isotype of antibody)
Whether the antibody reacts with the antigen on the cell or reacts with antigen before it interacts with the cell
The participation of complement
The participation of T cells
How is this reaction probably mediated by? A child stung by a bee experiences respiratory distress within minutes and lapses into unconsciousness.
IgE antibody
IgG antibody
Sensitized T cells
Complement
A patient with severe asthma gets no relief from antihistamines. The symptoms are MOST likely to be caused by:
IL-2
Leukotrienes
Serotonin
Bradykinin
Hypersensitivity to penicillin and hypersensitivity to poison oak are both:
Mediated by IgE antibody
Mediated by IgG and IgM antibody
Initiated by haptens
Initiated by Th2 cells
Which of the following regarding anaphylactic (type I) and immune complex (type III) hypersensitivities is the most accurate?
IgE is involved in both anaphylactic and immune complex hypersensitivity.
Complement is involved in both anaphylactic and immune complex hypersensitivities.
Less antigen is typically needed to trigger an anaphylactic reaction than an immune complex reaction
Neutrophils play a more important role in anaphylactic reactions than in immune complex reactions.
A delayed hypersensitivity reaction is characterized by:
Edema without a cellular infiltrate
An infiltrate composed of neutrophils
An infiltrate composed of helper T cells and macrophages
An infiltrate composed of eosinophils
