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WorksheetsCT I Pharm 5109
Total questions: 15
Worksheet time: 9mins
Which one of the following is a mixed neurotranmitter (both excitatory and inhibitory)
Glutamate
Dopamine
Histamine
Serotonin
Insulin is an example of ---------- receptor
Ionotropic
Metabotropic
Kinase-linked
Nuclear receptors
End bulb of Krause is an example of-
Mechanoreceptor
Baroreceptor
Chemoreceptor
Thermoreceptor
What is the full form of AMPA receptors?
Α - amino - 3 - hydro- 5 - methoxy - 4 - isoxozolepropionic acid
Α - amino - 3 - hydroxy - 5 - methyl - 4 - isoxozolepropionic acid
Α - amino - 3 - hydroxy - 5 - methyl - 4 - propionic acid
Α - amino - 3 - methyl - 4 - propionic acid
Functional ionotropic glutamate receptors are ------------ assemblies between subunits from ------------ major subfamilies.
Tetrameric, three
Pentameric, four
Trimeric, three
Pentameric, three
Open-channel block, a form of --------------- antagonism
competitive
uncompetitive
partial
reverse
Memantine is not used to treat--------------
Alzheimer's diseae
Dementia
Glaucoma
Seizures
Which of the following statement is not true?
Barbiturates are GABA agonists
Neurosteroids are GABA antagonists
Bicuculline is a GABA antagonist
Picrotoxin is a GABA antagonist
GABAa receptors are drawn from a pool of---------- distinct gene products
(a)
Which of the following statement is not true about GABAb receptors?
GABAb1 and GABAb2 both subunits are essential
The location of the recognition site is on GABAb1
Go or i are the location of the G protein-binding site on GABAb2
Baclofen is a receptor recognition site antagonist
Activation of α1 and α2-adrenergic receptors produces a slow -------------------- and ----------------------- , respectively.
(a)
----------------------- is a dopamine antagonist specifically for D4 receptor
(a)
Which of the following adreceptor coupling with G-protein is not true?
alpha-1 to Gq
alpha-2 to Go
alpha-1 to Gi
beta to Gs
Which of the following statement is true about adrenergic receptors?
Alpha-1 decreases blood pressure
Alpha-2 increases insulin release
Beta-1 increases myocardial contractility
Beta-2 decreases glucagon release
Which of the following is an example of beta-1 adrenergic receptor antagonist?
Terbutaline
Dobutamine
Atenolol
Butoxamine
