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CC2LAB

Total questions: 40

Worksheet time: 25mins

Name
Class
Date
1.

Which is oxidized?

(capital letter)

(a)  

2.

Reference Range of Lactate Dehydrogenase (LD/LDH)

a)

225 - 230 IU/L

b)

125 - 220 IU/L

c)

130 - 250 IU/L

d)

145 - 225 IU/L

3.

directly affects the heart (cardiac muscle tissues)

manifests as agina or Myocardial infarction and heart attack/acute myocardial infarction

a)

Coronary Heart Disease

b)

Cerebrovascular Disease

c)

Peripheral Arterial Disease

d)

Aortic Atherosclerotic Disease

4.

- vessels of the brain

- stroke and transient ischemic attacks (temporary paralysis)

a)

Coronary Heart Disease

b)

Cerebrovascular Disease

c)

Peripheral Arterial Disease

d)

Aortic Atherosclerotic Disease

5.

- deficiency in peripheral region like arms of legs

- acute localized pain to the arms and legs

a)

Coronary Heart Disease

b)

Cerebrovascular Disease

c)

Peripheral Arterial Disease

d)

Aortic Atherosclerotic Disease

6.

- formation of plaque

a)

Coronary Heart Disease

b)

Cerebrovascular Disease

c)

Peripheral Arterial Disease

d)

Aortic Atherosclerotic Disease

7.

Methods for LD/LDH

* not very specific and very sensitive measurement for LD activity

a)

Chemical inhibition: alpha hydroxybutyrate

b)

Wacker (pH 8.3-8.9)

c)

Wroblewski La Due (pH 7.1 - 7.4)

8.

Methods for LD/LDH

* more alkaline and almost neutral

* Lactate to pyruvate

* Increasing absorbance pattern

a)

Chemical inhibition: alpha hydroxybutyrate

b)

Wacker (pH 8.3-8.9)

c)

Wroblewski La Due (pH 7.1 - 7.4)

9.

Methods for LD/LDH

* decreasing

* Preferred method

* 3x faster than forward

a)

Chemical inhibition: alpha hydroxybutyrate

b)

Wacker (pH 8.3-8.9)

c)

Wroblewski La Due (pH 7.1 - 7.4)

10.

* Forward Method

*pH = 9

* Alkaline

* Decreasing

a)

Oliver - Rosalki

b)

Tanzer - Gilvarg

11.

* Reverse Method

*pH = 96.8

* Acidic

* Faster

a)

Oliver - Rosalki

b)

Tanzer - Gilvarg

12.

= CK1

= will migrate first as long as the condition is not in the heart or in the muscle; it can be associated with CKBB if there is elevation

a)

BB

b)

MB

c)

MM

d)

Macro

e)

Mitochondrial CK

13.

= CK2

= most significant marker

= indicator of heart atteck

a)

BB

b)

MB

c)

MM

d)

Macro

e)

Mitochondrial CK

14.

= CK3

= usually elevate after excercise then there is soreness of muscle

= Intramuscular injection - can last up to 1 week

a)

BB

b)

MB

c)

MM

d)

Macro

e)

Mitochondrial CK

15.

= bound to immunoglobulin

= clinical significance is not very correlational to the condition

a)

BB

b)

MB

c)

MM

d)

Macro

e)

Mitochondrial CK

16.

= indication of extensive tissue damage

= pattern is in the opposite way

= Migrate towards the cathode

a)

BB

b)

MB

c)

MM

d)

Macro

e)

Mitochondrial CK

17.

- rehulate the calcium dependent interactions of actin and myosin filaments

- Most preferred by physicians

- attached filament via tropomyosin

a)

Myoglobin

b)

Cardiac Troponins

c)

Creatine Kinase

d)

Lactate dehydrogenase

18.

- oxidoreductase

- conversion of lactate to pyruvate (or vise versa)

- RF: 125 - 220 IU/L

a)

Myoglobin

b)

Cardiac Troponins

c)

Creatine Kinase

d)

Lactate dehydrogenase

19.

- Coenzyme: Magnesium

- 3 normal and 2 abnormal isoenzymes

a)

Myoglobin

b)

Cardiac Troponins

c)

Creatine Kinase

d)

Lactate dehydrogenase

20.

- binds iron and oxygen in the muscle

- general marker of muscle injury - smooth cardiac and skeletal

- not a specific marke r

a)

Myoglobin

b)

Cardiac Troponins

c)

Creatine Kinase

d)

Lactate dehydrogenase

21.

skeletal muscle - predominant form of the serum

a)

CK-MM

b)

CK-BB

c)

CK - MB

22.

not always associated with brain injury (only if there is breakage of blood brain barrier)

widely distributed

a)

CK-MM

b)

CK-BB

c)

CK - MB

23.

specific to the heart

normal value : <6

a)

CK-MM

b)

CK-BB

c)

CK - MB

24.

RISE: 8 - 12 hrs

PEAK: 24 - 48hrs

DECLINE: 10 days

a)

Lactate Dehydrogenase

b)

CK-MB

c)

Troponin - I

d)

Troponin T

e)

Myoglobin

25.

RISE: 4 - 6 hrs

PEAK: 12 - 24hrs

DECLINE: 2 - 3 days

a)

Lactate Dehydrogenase

b)

CK-MB

c)

Troponin - I

d)

Troponin T

e)

Myoglobin

26.

RISE: 3 - 12 hrs

PEAK: 12 - 24hrs

DECLINE: 8 - 21 days

a)

Lactate Dehydrogenase

b)

CK-MB

c)

Troponin - I

d)

Troponin T

e)

Myoglobin

27.

RISE: 3 - 12 hrs

PEAK: 12 - 24hrs

DECLINE: 7 - 14 day

a)

Lactate Dehydrogenase

b)

AST

c)

Troponin - I

d)

Troponin T

e)

Myoglobin

28.

RISE: 1 - 4 hrs

PEAK: 6 - 9hrs

DECLINE: 18 - 24 hrs

a)

Lactate Dehydrogenase

b)

AST

c)

Troponin - I

d)

Troponin T

e)

Myoglobin

29.

RISE: 6- 8 hrs

PEAK: 18 - 24hrs

DECLINE: 4 - 5 days

a)

Lactate Dehydrogenase

b)

AST

c)

Troponin - I

d)

Troponin T

e)

Myoglobin

30.

- similar to myoglobin but more specific to the heart

- higher sensitivity but lower specific than troponins

- appear 3-6hrs after agina

a)

Heart type fatty acid binding protein

b)

ischemia - modified albumin (IMA)

c)

markers of plaque instability

d)

B-Type Natriuretic Peptide and C-reactive protein

e)

Homocysteine

31.

- predictor of AMI

- free radical can cause modification in albumin during ischemia

- binds cobalt

a)

Heart type fatty acid binding protein

b)

ischemia - modified albumin (IMA)

c)

markers of plaque instability

d)

B-Type Natriuretic Peptide and C-reactive protein

e)

Homocysteine

32.

- similar with troponin in early detection of AMI

* myeloperoxidase (MPO)

* C-reactive protein (CRP)

a)

Heart type fatty acid binding protein

b)

ischemia - modified albumin (IMA)

c)

markers of plaque instability

d)

B-Type Natriuretic Peptide and C-reactive protein

e)

Homocysteine

33.

- rule out congestive heart failure

a)

Heart type fatty acid binding protein

b)

ischemia - modified albumin (IMA)

c)

markers of plaque instability

d)

B-Type Natriuretic Peptide and C-reactive protein

e)

Homocysteine

34.

- atherosclerosis and thrombosis

a)

Heart type fatty acid binding protein

b)

ischemia - modified albumin (IMA)

c)

markers of plaque instability

d)

B-Type Natriuretic Peptide and C-reactive protein

e)

Homocysteine

35.

starch structure that in considered as the main chain/ straight chain

a)

∝\propto 1-4 glycosidic bonds

b)

∝\propto 1-6 glycosidic bonds

c)

α 1-5 glycosidic bonds

d)

α 1-7 glycosidic bonds

36.

starch structure that in considered as the side chain

a)

∝\propto 1-4 glycosidic bonds

b)

∝\propto 1-6 glycosidic bonds

c)

α 1-5 glycosidic bonds

d)

α 1-7 glycosidic bonds

37.

measures the disappearance of starch substrate

a)

Amyloclastic

b)

Saccharogenic

c)

Chromogenic

d)

Continuous monitoring

38.

measures the appearance of the product

a)

Amyloclastic

b)

Saccharogenic

c)

Chromogenic

d)

Continuous monitoring

39.

measures the increasing color from production of product coupled with a chromogenic dye

a)

Amyloclastic

b)

Saccharogenic

c)

Chromogenic

d)

Continuous monitoring

40.

coupling of several enzyme systems to monitor amylase activity

a)

Amyloclastic

b)

Saccharogenic

c)

Chromogenic

d)

Continuous monitoring

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