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WorksheetsLipid Metabolism
Total questions: 15
Worksheet time: 11mins
Which of the following are major end products of the digestion of TAG?
Phospholipids and amino acids
Glucose and fructose
2-MAG, 1-MAG, glycerol, and fatty acids
Cholesterol esters and bile salts
Which of the following molecules is essential for the emulsification and absorption of lipids in the small intestine?
Pancreatic Lipase
Gastrin
Bile Salts
Pepsin
The acyl-CoA formed in the cytosol is transported to the ___ for oxidation using a shuttle involving the intermediate formation of acyl- _____.
mitochondrial matrix, coenzyme A.
mitochondrial matrix, carnitine.
microsomes, Coenzyme A.
None of the above
The complete beta-oxidation of palmitoyl CoA yield
8 molecules of Acetyl CoA and 7 NADH
8 molecules of Acetyl CoA and 7 FADH2
8 molecules of Acetyl CoA, 7 NADH, and 7 FADH2
8 molecules of Acetyl CoA and 16 NADPH
Which of the following step is committed to the formation of ketone bodies?
Formation of Acetoacetyl CoA catalyzed by thiolase
Formation of HMG CoA catalyzed by HMG CoA synthase
Splitting of HMG CoA to acetyl CoA and acetoacetate catalyzed by HMG CoA lyase
Reduction of acetoacetate to Beta-hydroxybutyrate catalyzed by Beta-hydroxybutyrate dehydrogenase
________ Substrate which is required _______ enzyme for the formation of Malonyl CoA during Fatty acid Synthesis
Acetyl CO-A, Acetyl CO-A Carboxylase
Acetyl CO-A, Acetyl CO-A Decarboxylase
Acetyl CO-A, Acetyl CO-A dehydrogenase
Acyl CO-A, Acyl CO-A Carboxylase
Synthesis of fatty acid requires _____, while degradation requires _____and ______
NADPH, NAD & FAD
NADH, NAD & FAD
NADPH, NADH & FADH2
FAD, NAD & FAD
An enzyme required for the synthesis of ketone bodies as well as cholesterol is
Acetyl CoA carboxylase
HMG CoA synthase
HMG CoA reductase
HMG CoA lyase
The highest phospholipids content is found in ________
Chylomicrons
VLDL
LDL
HDL
which statement depicts the exact difference between HDL 3 & HDL 2
HDL 3 have high Cholesterol and high triglyceride level than HDL2 molecule
HDL 2 have high cholesterol and low triglyceride than HDL 3
HDL 3 have high cholesterol and low triglyceride than HDL 2
HDL 3 have low cholesterol and low triglycerides than HDL 2
HDL is a type of lipoprotein that is important for acquiring cholesterol from VLDL and chylomicrons.
Which of the following proteins are important for HDL function?
Apo A-I
Lecithin-Cholesterol Acyltransferase (LCAT)
Cholesteryl Ester Transport Protein (CETP)
All Of Them
Which Statement depicts the Structure of Cholesterol
It has 24 carbon atoms; 3 hydroxyl group on 3,7,12 carbon atom; Double bond between 5 and 6 carbon atoms and eight
carbon side chain
It has 27 carbon atoms; 1 hydroxyl group on 3rd carbon atom; Double bond between 5 and 6 carbon atoms and 8
carbon side chain.
It has 30 carbon atoms; One hydroxyl group on 3rd carbon atom; Double bond between 5 and 6 carbon atoms and also between 24 and 25 th carbon and also has eight
carbon side chain
It has 27 carbon atoms; One hydroxyl group on 3rd carbon atom; Double bond between 5 and 6 carbon atoms and 10
carbon side chain
The rate-limiting enzyme of the cholesterol biosynthetic pathway is _______ and it requires ______ as a cofactor.
HMG CO-A Synthase, NADH
HMG CO-A Reductase, NADPH
HMG CO-A synthase, NADPH
HMG CO-A Lyase, NADPH
Primary bile acids leads to the production of corresponding bile salts
True
False
Major Apo protein present, during synthesis of chylomicrons is ______
Apo-b100
apo-a1
apo-c2
apo-b48
