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MI EOC Review

Total questions: 53

Worksheet time: 3hrs 39mins

Name
Class
Date
1.

5.) In what order should you add the reagents to perform an ELISA test?

a)

a.) Primary antibody, antigen sample, enzyme-linked secondary antibody, substrate

b)

b.) Antigen sample, primary antibody, enzyme-linked secondary antibody, substrate

c)

c.) Substrate, enzyme-linked secondary antibody, antigen samples

d)

d.) Primary antibody, enzyme-linked secondary antibody, antigen samples, substrate

2.

7.) An outbreak of a disease has been spreading through a small community. Using samples taken from infected patients, which of the following tests BEST enable doctors at the CDC to identify an unknown pathogen from the outbreak?

a)

a.) Determine the sequence of the pathogen's DNA with an automated sequencer and then amplify key genes using PCR.

b)

b.) Determine the sequence of the pathogen's DNA using recombinant DNA methods and then amplify the sequence using PCR.

c)

c.) Use an automated sequencer to determine the nucleotide sequence of the samples, then compare these sequences with known organisms using BLAST.

d)

d.) Use PCR to amplify the genome of the infected patients, then BLAST the genome results.

3.

9.) What career combines molecular biology and computer analysis?

a)

a.) diagnostic imaging

b)

b.) gene therapist

c)

c.) bioinformatics

d)

d.) microbiology

4.

11.) Which structure contains accessory genes such as antibiotic resistance and can be used for recombinant DNA?

a)

a.) pili

b)

b.) plasmid

c)

c.) flagella

d)

d.) capsule

5.

14.) Structure 9 in the diagram is the

a)

a.) vestibule

b)

b.) semicircular canals

c)

c.) cochlea

d)

d.) cochlear nerve

6.

15.) Which of the following shows the correct order of how sound travels through the ear?

a)

a.) pinna, tympanic membrane, stapes, cochlea, cochlear nerve

b)

b.) auditory canal, stapes, incus, cochlea, vestibular nerve

c)

c.) pinna, tympanic membrane, vestibule, Eustachian tube

d)

d.) tympanic membrane, incus, malleus, semicircular canal

7.

18.) During a Rinne test, what does it mean when a patient can hear the tuning fork longer through bone conduction than through air conduction?

a)

a.) conductive hearing loss

b)

b.) sensorineural hearing loss

c)

c.) complete hearing loss

d)

d.) a problem with the brain's ability to process sound

8.

19.) Which of the following is true about cochlear implant technology?

a)

a.) The entire deaf community supports cochlear implants as a treatment for hearing loss.

b)

b.) Cochlear implants are effective for everyone and have predictable results.

c)

c.) A cochlear implant is an option for treating profound hearing loss.

d)

d.) A cochlear implant is necessary for someone with hearing loss to function in mainstream society.

9.

In the picture of the bacteria, letter A is the

a)

Nucleoid

b)

Flagella

c)

Pili

d)

Capsule

10.

In the picture of the bacteria, letter F is the

a)

Capsule

b)

Cytoplasm

c)

Plasmid

d)

Cell Wall

11.

In the picture of the bacteria, letter E is the

a)

Nucleotid

b)

Cytoplasm

c)

Plasmid

d)

Ribosome

12.

In the picture of the bacteria, letter D is the

a)

Flagella

b)

Pili

c)

Plasmid

d)

Ribosome

13.

Which type of bacteria has extra lipopolysaccharide layer?

a)

Gram Positive

b)

Gram Negative

14.

Transformation occurs when bacteria

a)

change from one type of bacteria to a different form of bacteria.

b)

change from being gram positive to gram negative

c)

take up DNA from a different bacterial cell when the donor releases it.

d)

DNA is transferred directly into the bacterial cell through a connecting tube.

15.

The best description of a "superbug" is a bacteria that

a)

is present in large amounts.

b)

has resistance to multiple antibiotics

c)

is a combination of multiple bacteria.

d)

is the last bacteria to survive after a round of antibiotics.

16.

Which class of antibiotics interupts ribosome function (protein synthesis)?

a)

Flouroquinolones

b)

Beta-lactams

c)

Tetracylines

d)

Sulfonamides

17.

Which class of antibiotics disrupts folic acid synthesis (cell growth)?

a)

Flouroquinolones

b)

Beta-lactams

c)

Tetracylines

d)

Sulfonamides

18.

Which class of antibiotics interferes with the undwinding of supercoiled DNA (DNA replication)?

a)

Flouroquinolones

b)

Beta-lactams

c)

Tetracylines

d)

Sulfonamides

19.

The auditory nerve is shown at

a)

D

b)

H

c)

I

d)

J

20.
How does increasing the amplitude of a sound wave affect the sound?
a)
it makes the sound louder
b)
it makes the sound travel faster
c)
it increases the wavelength of the sound
d)
it increases the frequency of the sound
21.

Programmed cell death

a)

Apoptosis

b)

Metastasis

c)

Oncogene

d)

Nuclear blebbing

22.

Gene having potential to cause a normal cell to become cancerous

a)

Tumor suppressor gene

b)

Oncogene

c)

Proto-oncogene

d)

Risk factor

23.

Bone cancer

a)

Osteosarcoma

b)

Osteosis

c)

Osteoectomy

d)

Osteostasis

24.

Gene that inhibits cell division

a)

Tumor suppressor gene

b)

Proto-oncogene

c)

Oncogene

d)

Risk factor

25.

If 1 mL sample is put into tube #1 that has 24 ml diluent, what is the tube dilution and final dilution? Select 2 answers.

a)

Tube 1/25

b)

Final 1/50

c)

Tube 1/50

d)

Final 1/25

26.

How many Bp (base pairs) is the band is sample A?

a)

1200bp

b)

1000bp

c)

500bp

d)

2--bp

27.
How many of these restriction enzymes produce sticky ends?
a)
2
b)
4
c)
5
d)
3
28.
If a bacteria receives DNA from a viral vector, the process is called 
a)
conjugation
b)
transduction
c)
transformation
d)
viral infusion
29.

Human Leukocyte Antigens (HLA) are responsible for

a)

stimulating the immune response to recognize tissue as self nor non-self

b)

measuring the patients sensitivity to donor antigens

c)

the state of mutual tolerance between tissues that allows them to be grafted effectively

d)

the genes that encode a large set of cell surface proteins

30.

Gene alleles (a copy from mom or dad) are written with ______ when Dominant (shows the trait such as Brown hair):

a)

Upper case letters

b)

Lower case letters

c)

numbers

d)

alpha-numeric code

31.

Gene alleles (a copy from mom or dad) are written with ______ when Recessive:

a)

Upper case letters

b)

Lower case letters

c)

numbers

d)

alpha-numeric code

32.

The correct steps, in order, to perform PCR is

a)

denaturation, annealing, extension

b)

annealing, extension, denaturing

c)

extension, denaturation, annealing

d)

annealing, prometaphase, polymerase

33.

Why does PCR require a specific type of polymerase?

a)

Taq polymerase can withstand the range of temperatures in PCR without denaturing.

b)

Taq polymerase is the most common type of polymerase.

c)

Taq polymerase is the most inexpensive type of polymerase.

d)

A specific type of polymerase is unnecessary.

34.

The physical insertion of "good" copies of a gene into the cells of a person with a genetic disorder in an attempt to correct the disorder

a)

Karyotype

b)

Gene therapy

c)

Selective breeding

d)

Cloning

35.

Which of the following base pairs is matched correctly?

a)

Guanine and Thymine

b)

Cytosine and Adenine

c)

Adenine and Thymine

d)

Thymine and Cytosine

36.

What is the purpose of Polymerase Chain Reaction (PCR) in the process of sequencing DNA?

a)

To separate DNA fragments by size

b)

To synthesize copies of template DNA

c)

To change the structure of template DNA

d)

To terminate the elongation of a DNA strand

37.

During which PCR step do primers form complementary base pairs with single-stranded template DNA?

a)

Denaturation

b)

Annealing

c)

Extension

d)

Synthesis

38.

DNA has a ___________ charge and will migrate through a gel towards the ___________ electrode.

a)

positive, negative

b)

positive, positive

c)

negative, positive

d)

negative, negative

39.

Larger DNA fragments move through a gel _____________ smaller DNA fragments.

a)

faster than

b)

at the same rate as

c)

slower than

d)

not at all, compared to

40.

Insulin moves blood glucose primarily into _____________ cells to be used as energy.

a)

islet (of Langerhans)

b)

fat

c)

muscle

d)

liver

41.

Insulin signals _________ cells to store glucose as glycogen.

a)

islet (of Langerhans)

b)

fat

c)

muscle

d)

liver

42.

An enzyme that cut DNA molecules at a specific “recognition site” is called

a)

Restriction enzyme

b)

DNA polymerase

c)

RNA polymerase

d)

Taq polymerase

43.
In order to insert a human gene into plasmid, both must 
a)
code for the same gene product.
b)
be cut by the same restriction enzyme.
c)
originate from the same type of cell.
d)
have identical sequences.
44.

Which substance is used to separate proteins by size?

a)

sodium docecyl sulfate

b)

calcium chloride

c)

2-mercaptoethanol

d)

polyacrylamide

e)

wash buffer

45.

Electrophoresis separates molecules based on their relative

a)

size

b)

sequence

c)

shape

d)

function

46.

What are erythrocythes?

a)

red blood cells

b)

white blood cells

c)

plasma

d)

platelets

47.

What are thrombocythes?

a)

heart vessels

b)

platelets

c)

white blood cells

d)

pulmonary vein

48.

What are leukocytes?

a)

red blood vessels

b)

plasma

c)

white blood cells

d)

platelest

49.

What type of antigens can be found on the surface of RBC's when someone has blood type O?

a)

A

b)

B

c)

A and B

d)

none

50.

What type of antigens can be found on the surface of RBC's when someone has blood type AB?

a)

A

b)

B

c)

A and B

d)

none

51.

What cells produce antibodies?

a)

red blood cells

b)

white blood cells

c)

Plasma cells

d)

Platelets

52.

Which class of antibiotics interferes with the bacterial cell wall?

a)

Flouroquinolones

b)

Beta-lactams

c)

Tetracylines

d)

Sulfonamides

53.

How many of these restriction enzymes produce blunt ends?

a)

2

b)

4

c)

5

d)

3