What treatment is preferred for subacute and chronic pain?

What treatment has a ceiling effect?

What nonopioid analgesic has AE of hepatotoxicity that is increased in liver disease and EtOH abuse? Also known as Tylenol.

What nonopioid analgesic has MOA of relieving pain and inflammation by blocking prostaglandin synthesis via COX enzyme inhibition?

What is NOT a main NSAID AE?

What is NOT an adjuvant or co-analgesic?

What anticonvulsant is NOT schedule V and does NOT need renal adjustments?

What medication is used for mild/mod nociceptive pain?

What medication is used for mild/mod pain that may be inflammatory in nature?

What medication is used for painful diabetic neuropathy, MDD, GAD, fibromyalgia, and chronic musculoskeletal pain?

What medication is DOC for trigeminal neuralgia?

What medication is used for treatment of neuropathic pain d/t cord compression, HA d/t increased ICP, and arthritic pain?

What medication is used for post-herpetic neuralgia, peripheral neuropathy, and well-locaized pain?

What medication has MOA of noncompetitive NMDA receptor antagonist that modulate central sensation, hyperalgesia, and opioid tolerance?

What is the correct order for management of back pain per the American College of Physicians guildines?

What is NOT a recommended treatment for back pain per the American Academy of Pain Medicine/North American Spine Society?

What type of opioid should be used initially?

All of the following make opioid analgesics differ from one another, but activity depends on _____ for opiate receptors.

What opioid medication is converted to morphine via CYP2D6, has antitussive effects, and AE of resp depression + overdose?

What opioid medication has no active metabolites and is available in injectable (most rapid onset & shortest duration), transdermal patch, sublinqual tablet, transmucosal, and intranasal?

Fentanyl transdermal patches are NOT indicated for opioid-naive patients. What is the cut off for patients to no longer be considered opioid-naive?

When is peak concentration after inital fentanyl transdermal patch applicaiton?

What opioid medication is most commonly used in combo with APAP and is NOT indicated for PRN use?

What opioid medication has no active metabolites and is also known as Dilaudid?

What opioid medication has active metabolite of normeperidine and is NOT recommended for the treatment of pain, but is used for drug-induced rigors or shivering?

What opioid medication is a mu agonist + NMDA receptor antagonist that has a long (but variable 1/2 life) and is inidcated for detoxification and maintenance of treatment of opioid used disorder?

What opioid medication is best used for true allergies/ADE, significant renal impairment, cost, significant chronic pain, and refractory pain?

Methadone can cause dose-dependent QT prolongation. A value of __(1)__ means consider alternatives, discuss risk/benefits, and frequent monitoring. A value of __(2)__ means do not initiate, consider D/C or reducing dose, eliminate contribuating factors.

What opioid medication is the GOLD STANDARD of opioids?

What opioid medication has significant first-pass effect?

What are the atypical opioids? (choose 2)

Mixed action opioids exhibit agonist and antagonist activity. What is NOT a mixed action opioid?

Pt presents with dysphoria, restlessness, rhinorrhea, lacrimation, yawning, mydriasis, myalgias/arthralgias, piloerection, N/V/D, and abd cramping. All of the following are possible treatments, but what is the best?

Pt presents with dysphoria, restlessness, rhinorrhea, lacrimation, yawning, mydriasis, myalgias/arthralgias, piloerection, N/V/D, and abd cramping. What is NOT something to be used for symptomatic management?

What opioid is NOT preferred for renal insufficiency?

All of the following opioids should be AVOIDED in renal insufficiency, EXCEPT one that is preferred?

All of the following opioids should be AVOIDED in hepatic dysfunction, EXCEPT one that is preferred?

Breakthrough pain should be managed with ER opioid formalations.

One opioid dose should be ___ of the total daily dose.

If a pt is already on opioid therapy for mod/severe pain, by how much do you increase their dose?

If a pt is already on opioid therapy for mild/mod pain, by how much do you increase their dose?

There is concern for incomplete cross tolerance when transitioning opioids, so you should __(1)__ starting dose of new agent by __(2)__.

How much should a rescue dose be?

Pt is currently taking Morphine ER 60 mg PO TID and Oxycodone 10 mg PO q6h PRN for breakthrough pain. She uses an average of 1 tablet per day for breakthrough pain. You want to change her morphine ER to oxycodone ER. What is an appropriate oxycodone ER dose? ((Morphine 25 mg PO = Oxycodone 20 mg PO))

What is the MC ADE to opioids?

Opioids can cause constipation and tolerance does NOT develop.

What is the treatment of choice for constipation prophylaxis with opioids?

Pt who just started opioids presents with elevated IgE level, severe hypotension, severe skin reaction, difficulting breathing/swallowing/speaking, or angioedema of the tongue/face/neck. What is NOT a possible part of management?

Pt who just started opioids presents with mild site reaction, itching, flushing, sweating, and mild hypotension. You suspect something caused by histamine release. What is NOT a possible part of management?

What opioid is classified as a diphenylheptane?

What opioids are classified as a phenylpiperidine? (choose 2)

Morphine, codeine, hydrocodone, hydromorphone, levorphanol, oxycodone, oxymorphone are what chemical classification?

Pt presents to the ED with respiratory depression, pinpoint pupils, and decreased consciousness. What is the treatment of choice?

What is NOT treatment for opioid use disorder?