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Pharm FINAL TEST REVIEW

Total questions: 16

Worksheet time: 9mins

Name
Class
Date
1.

The advance practice provider understands antibiotic resistance occurs in the penicillin based drugs via which of the following mechanisms?

a)

Inhibition of folatesynthesis

b)

Inhibition of cell wall synthesis

c)

RNA transcription inhibition

d)

Beta-lactamase destruction of the beta-lactam ring

2.

All of the following medications should be held for 2 hours before administering oral antibiotics (especially fluoroquinolones) to improve absorption EXCEPT

a)

Antacids

b)

Zinc

c)

Aspirin

d)

Multi-vitamins

3.

This class of antibiotics has a black box warning for increased risk or tendonitis, tendon rupture, and

a)

Beta-lactams

b)

Tetracyclines

c)

Sulfonamides

d)

Fluoroquinolones

4.

For which of the following is a fentanyl patch contraindicated?

a)

A patient who has back pain for the last 4 years from multiple herniated discs

 

b)

A patient who wants to minimize pill burden for pain control

c)

A patient who complains of severe pain in the immediate postoperative period.

d)

A patient with chronic myelogenous leukemia refractory to treatment

5.

The provider understands opiods may commonly cause which of the following side effects? Pick all that apply

a)

Diarrhea

b)

Sedation

c)

Itching

d)

AMS

e)

Respiratory Rate less than 12

6.

Which of the following variables should be considered when prescribing medications? Pick all that apply.

a)

Prescriber's comfort level with the patient's cultural beliefs.

b)

Insurance coverage

c)

Language barrier

d)

Lack of trust in medical professionals

e)

Allergies

7.

This agent is NOT susceptible to inactivation by bacterial beta lactamases

a)

Ampicillin

b)

Oxacillin

c)

Amoxicilin Clavulanate (Augmentin)

d)

Penicillin G

8.

Fill in the blank. Fluoroquinolones have an increased risk of_________ when combined with__________.

a)

Mental status changes; anti-hypertensives

b)

Discoloration of tooth enamel; tetracyclines

c)

Tendon rupture; corticosteroids

d)

QTc interval; acetaminophen

9.

______________and_______________

are indicated for slowing the progression of symptoms of Alzheimer’s Disease

a)

Galantamine (Razadyne), Sertraline (Zoloft)

b)

Memantine (Namenda), Venlaxafine (Effexor)

c)

Donazepil (Aricept), Memantine (Namenda)

d)

Risperidone (Risperdal), Memantine (Namenda)

10.

A 22-year old patient presents to the clinic with a sore throat for 4 days with accompanying fever. The patient is positive for Streptococcus. Which of the following cephalosporins is indicated?

a)

Ceftriaxone(Rocephin)

b)

Cefepime(Maxipime)

c)

CeftolozoneTazobactam(Zerbaxa)

d)

Cephalexin(Keflex)

11.

The bioavailability of oral medications may be less than intravenous medications due to which of the following processes?

a)

The presence of competing medications in the gastrointestinal tract

b)

The patient's renal clearance.

c)

The first-pass effect

d)

The presence of CYP-450 enzymes

12.

The advance practice registered nurse (APRN) assesses a child with a mild upper respiratory infection, which is most likely viral. The mother of the child insists on the need for a prescription of an antibacterial medication. The principles of the role of the APRN in the prescribing process dictate the APRN to consider which of the following in regards to this scenario?

a)

The APRN understands the antibiotic may help due to the placebo effect.

b)

The APRN understands the need to consider the parent's wishes when prescribing medications if the risks of adverse events are low.

c)

The APRN understands it is unethical tobe pressured to prescribe inappropriate medications.

d)

The APRN should always prescribe an antibacterial medication for a viral infection.

13.

Codeine has an FDA black box warning against its use in children due to which of the following?

a)

Children with a CYP450 mutation should not receive any opiod medications for analgesia.

b)

Children with a CYP450 mutation may have dangerous supratherapuetic effects

c)

Children with a CYP450 mutation have need to be dosed at higher levels to achieve a therapeutic effect

d)

Children with a CYP450 mutation who are ultra rapid metabolizers may have no analgesic effect

14.

When prescribing opiods, the advance practice provider understands which of the following to be appropriate?

a)

Methadone (Methadose) is safely prescribed by a novice provider

b)

Hydromorphone (Dilaudid) is about 5 times the potency of morphine sulfate (MS Contin)

c)

Methadone (Methadose) is safely prescribed by a novice provider

d)

Fentanyl (Durogesic) is available in combination with acetaminophen (Tylenol),

15.

The half-life of ibuprofen (Advil) is about 2 hours. Which of the following is NOT appropriate regarding the provider's understanding of the half-life of ibuprofen?

a)

Understanding the half-life of a medication will help the provider time the next dose.

b)

After hours, the patient will no longer feel the effects of the ibuprofen and will need to be re-dosed.

c)

If the patient does not feel a therapeutic effect after the first half-life, the dosage may need to be increased or another medication may need to be considered

d)

The effect of the ibuprofen will diminish almost completely within about 6-8hours.

16.

Which of the following is an anti anaerobic medication that has excellent bioavailability and should be considered for an intra abdominal infection?

a)

Levofloxacin

b)

Metronidazole

c)

Linezolid

d)

Quinupristin/Dalfopristin(Synercid