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WorksheetsBIOCEL 06
Total questions: 20
Worksheet time: 11mins
Name
Class
Date
1.
Which of the following is INCORRECT evidence to support the endosymbiotic theory?
a)
Mitochondria and bacteria differ in size
b)
Mitochondria are self-repeating bodies like microscopic organisms
c)
Mitochondrial ribosomes, and enzymes are similar to the bacteria
d)
Mitochondria have their own particular DNA
e)
All are incorrect
2.
Respiratory subunit in mitochondria not encoded by its genome
a)
complex II
b)
complex I
c)
complex III
d)
complex IV
e)
complex V
3.
The ________________ are functions of the mitochondria
a)
All answers are correct
b)
synthesis/breakdown/interconversion of amino acids and participate in the urea cycle
c)
cell signaling via ROS and calcium storage
d)
cell death and biosynthesis
e)
ATP production and cell metabolism regulation
4.
mitochondrial-nuclear crosstalk is so important for the__________________.
a)
All answers are correct
b)
correct functioning of respiratory chain enzymes
c)
correct folding and assembly of respiratory chain enzymes
d)
correct import of respiratory chain enzymes
e)
correct synthesis of respiratory chain enzymes
5.
The nuclear DNA interact with the mitochondria by _________________.
a)
encoding all components of the protein import machinery
b)
regulating cell metabolism
c)
participating in the urea cycle
d)
they do not interact
e)
limiting mitochondrial repair system
6.
Are mitochondria the same in every tissue?
a)
All answers are correct
b)
No, there are differences between tissues in mitochondrial number, function, protein composition and morphology.
c)
No, each cell type develops and maintains a specific oxidative phosphorylation (OXPHOS) capacity to satisfy its metabolic and energetic demands
d)
No, the number of mitochondria in a cell can vary widely by tissue.
e)
No, mitochondria are found in almost all body cells, except for a few, and they differ among each other cells.
7.
It is a possible source of mutations in mitochondria?
a)
All answers are correct
b)
nuclear DNA: mendelian inheritance
c)
cytoplasmic mtDNA: non-mendelian; maternal inheritance
d)
X-linked
e)
loss of wild-type mtDNA
8.
The mtDNA adapt to the_____________.
a)
Nuclear transcription, cytoplasmic translation and signal sequence
b)
Nuclear transcription and signal sequence
c)
Cytoplasmic translation and nuclear transcription
d)
Signal sequence and cytoplasmic translation
e)
None is correct
9.
What is the role of mitochondrial fusion and fission?
a)
To maintain optimal function in energy generation
b)
To increase the number of mitochondria in a cell
c)
To decrease the number of mitochondria in a cell
d)
To prevent the formation of reactive oxygen species
e)
To regulate the cell cycle
10.
What is the consequence of defects in the machinery mediating mitochondrial fusion and fission?
a)
A range of diseases that especially affect the nervous system
b)
Increased resistance to oxidative stress
c)
Increased efficiency in energy generation
d)
Increased mobility within the cell
e)
Increased homogenization of the mitochondrial population
11.
What diseases strongly affect mitochondrial dynamics?
a)
Neurodegenerative diseases and cancer
b)
Cardiovascular diseases and diabetes
c)
Infectious diseases and autoimmune diseases
d)
Respiratory diseases and gastrointestinal diseases
e)
Musculoskeletal diseases and dermatological diseases.
12.
What is the name of the family of GTPases that mediate mitochondrial fusion and fission?
a)
Dynamin
b)
Actin
c)
Myosin
d)
Kinesin
e)
Tubulin
13.
What is the consequence of blocking mitochondrial fission?
a)
Mitochondria become elongated and show more interconnections
b)
Mitochondria become fragmented into small spheres
c)
Mitochondria become more efficient at energy generation
d)
Mitochondria become more resistant to oxidative stress
e)
Mitochondria become more mobile within the cell
14.
What is the function of the mitochondrial ATP synthase?
a)
To produce ATP from ADP and phosphate ions
b)
To produce ADP from ATP and phosphate ions
c)
To produce phosphate ions from ATP and ADP
d)
To produce ATP from glucose and oxygen
e)
To produce glucose from ATP and oxygen
15.
What is the function of cytochrome c in the mitochondrial cristae?
a)
To shuttle electrons from complex III to complex IV
b)
To shuttle electrons from complex I to complex II
c)
To shuttle electrons from complex IV to complex III
d)
To shuttle electrons from complex II to complex I
e)
To shuttle electrons from complex III to complex II
16.
Why is it important for cytochrome c to remain in the mitochondrial cristae?
a)
Because if released into the cytoplasm, it triggers apoptosis
b)
Because it is needed for the synthesis of ATP
c)
Because it is needed for the synthesis of heme groups
d)
Because it is needed for the synthesis of iron-sulfur clusters
e)
Because it is needed for the synthesis of phospholipids
17.
What is the function of the mitochondrial inner membrane cristae?
a)
To increase the surface area for protein complexes involved in energy conversion
b)
To store ATP
c)
To synthesize lipids
d)
To produce glucose
e)
To degrade proteins
18.
What is the effect of aging on mitochondrial function?
a)
It can lead to decreased efficiency of energy conversion
b)
It can lead to increased efficiency of energy conversion
c)
It has no effect on energy conversion
d)
It can lead to increased ATP production
e)
All are incorrect
19.
What is the function of the mitochondrial outer membrane?
a)
To act as a barrier between the cytoplasm and the intermembrane space
b)
To synthesize ATP
c)
To produce glucose
d)
To store calcium ions
e)
All are incorrect
20.
What is the significance of the similarities between the energy-conversion systems of mitochondria and chloroplasts?
a)
They suggest a common evolutionary origin
b)
They suggest that mitochondria and chloroplasts perform the same functions
c)
They suggest that mitochondria and chloroplasts are interchangeable
d)
They suggest that mitochondria and chloroplasts are unrelated
e)
All are incorrect
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