NEW
Font size
S
M
L
XL
WorksheetsBIOCEL 08
Total questions: 20
Worksheet time: 10mins
Name
Class
Date
1.
What is the reversible enzyme that can also serve as a proton pump?
a)
ATP synthase
b)
Cytochrome c oxidase
c)
NADH dehydrogenase
d)
Succinate dehydrogenase
e)
Is this real life or just a simulation?
2.
What is the energy charge hypothesis?
a)
Regulatory enzymes are sensitive to ATP levels
b)
ADP is allosterically activated by AMP
c)
ATP is allosterically activated by AMP
d)
ATP is not involved in cell metabolism
e)
Coffee, the elixir of productivity!
3.
Which mitochondrial fission-and fusion-related proteins are involved in cell death?
a)
Drp1 and mitofusin (Mfn1 and Mfn2)
b)
Ribosome and Golgi Apparatus
c)
Lysosome and Peroxisome
d)
Nucleus and Endoplasmic Reticulum
e)
Life would be easier with a "Ctrl+Z" option
4.
What are metabolic intermediates?
a)
Compounds formed in each step along the pathway
b)
Compounds formed at the end of the pathway
c)
Compounds formed at the beginning of the pathway
d)
Compounds formed in the middle of the pathway
e)
Who needs sleep when you have data to analyze?
5.
Mitchell's chemiosmotic theory suggested that a high concentration of protons outside the mitochondrial membrane:
a)
Generated a voltage and a protonmotive force which helped drive the ATP synthase
b)
Reduced the oxidation potential
c)
Made the interior of the membrane highly acidic
d)
Caused the exterior of the membrane to become highly basic
e)
"PhD" could stand for "Permanent Head Damage"
6.
Which metabolic pathway is centrally mitochondrial?
a)
TCA cycle
b)
Proline and ornithine metabolism
c)
Glycolysis
d)
Fatty acid oxidation
e)
My thesis is like a Rubik's Cube, but with words and fewer colors.
7.
During electron transport, protons are pumped out of the mitochondrion at each of the major sites except for:
a)
Succinate:CoQ reductase
b)
NADH:CoQ reductase
c)
Reduced:cyt c reductase
d)
Cytochrome oxidase
e)
When in doubt, add more citations. It's the PhD way.
8.
Is/are protein translocators in mitochondria's inner membrane:
a)
TIM 22 & 23
b)
TOM
c)
OXA
d)
SAM
e)
My brain is 90% coffee and 10% thesis.
9.
The _________ is an enzyme that donates electrons to the electron transport chain from their flavin (FAD) prosthetic group.
a)
Succinate dehydrogenase
b)
acyl-CoA monohydrogenase
c)
glycerol phosphate bihydrogenase.
d)
ATPase
e)
Life is all about finding the perfect balance between research and snacks.
10.
In normal mitochondria, the rate of electron transfer is tightly coupled to the demand for ATP. When the rate of use of ATP is relatively low, the rate of electron transfer is low; when the demand for ATP increases, the electron-transfer rate increases. Under these conditions of tight coupling, the number of ATP molecules (P) produced per atom of oxygen (O) consumed when NADH is the electron donor
a)
P/O ratio
b)
Porphyrin
c)
Positive
d)
Brown fat
e)
I need vacations!
11.
Allowing H+ through the IMM passively: disrupts the H+ gradient without stopping electron transport
a)
Uncoupling electron transport from ATP synthesis
b)
Oxidation of NADH or FADH2 coupled to reduction of O2
c)
Nonshivering thermogenesis
d)
Ensures O2 is converted to H2O
e)
I am hungry!
12.
NADH dehydrogenase FMN --> FMNH2 NADH + H+ --> NAD+ acceptor of electrons form NADH moved four hydrogen ions from matrix to inter membrane space electrons then transferred to ubiquinone
a)
Complex I
b)
Complex II
c)
Complex III
d)
Complex IV
e)
Complex V
13.
Which of the following is the correct name for Mitochondrial Complex IV?
a)
Cytochrome c oxidase
b)
ATP synthase
c)
NADH dehydrogenase
d)
Succinate dehydrogenase
e)
Cytochrome P450
14.
Which molecule catalyzes the transfer of electrons from Complex III to Complex IV?
a)
Cytochrome c (reductase-oxidase)
b)
Coenzyme Q
c)
H-dependent ATPase
d)
Succinate:CoQ
e)
NADH:CoQ reductase
15.
Which molecule catalyzes the transfer of electrons from NADH:CoQ reductase and Succinate:CoQ reductase to Reduced:cyt c reductase?
a)
Ubiquinone
b)
ATPase
c)
Cytochrome c
d)
Succinate dehydrogenase
e)
phosphate dehydrogenase
16.
Defects in mitochondrial transport are a suspected cause of diseases including Alzheimer's, Huntington's and Parkinson's. ATP hydrolysis fuel mitochondrial protein directional transport at:
a)
the outer membrane and into the matrix space
b)
the intermembrane and into the matrix space
c)
the cristae and intermembrane
d)
the outer, inner and inter membrane
e)
the intermembrane and inner membrane
17.
_____________ are mitochondrial machineries for protein import and assembly
a)
TIM/TOM complex
b)
TIC/TOC complex
c)
TIC/TAC complex
d)
TIM/TOC complex
e)
TIC/TOM complex
18.
The cytochrome c oxidase complex
a)
All answers are correct
b)
accepts electrons from cyt c.
c)
donates four electrons to O2.
d)
produces 2 H2O per O2 reduced.
e)
pumps 2 protons out of the matrix space.
19.
Coenzyme Q is involved in electron transport____________.
a)
as a lipid-soluble electron carrier.
b)
as a water-soluble electron donor.
c)
as a covalently attached cytochrome cofactor.
d)
as a water-soluble electron acceptor.
e)
directly to O2.
20.
The interior of the inner mitochondrial membrane is relatively impermeable to ionic substances because:
a)
The inside portion of the membrane is a lipid bilayer and relatively nonpolar
b)
The inside of the membrane is filled with water
c)
The outer portions of the membrane nearest the cytoplasm or mitochondrial matrix are relatively polar
d)
The membrane is relatively polar
e)
The membrane itself is ionic
Reset
