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Worksheets

iPSC Super Fun Time

Total questions: 15

Worksheet time: 21mins

Name
Class
Date
1.

Please draw your mood/vibe

2.

How confident do you feel selling to iPSC clients, from a portfolio perspective?

a)

OI incoming

b)

OI maybe

c)

OI doubtful

d)

No OI

3.

For you, how is selling to an iPSC customer unique from say, an MSC/Immune cell customer?

4 lines
4.

Who won half of the Nobel Prize in Physiology or Medicine for their work showing that adult cells can be reprogrammed?

a)

Fusajiro Yamauchi

b)

Soichiro Honda

c)

Shinya Yamanaka

d)

Haruki Murakami

5.

The work of Yamanaka and his team in successfully creating iPSC cells was an effort to match the functionality of what kind of cell?

a)

Endothelial Cells

b)

Embryonic Stem Cells

c)

Mesenchymal Stem Cells

d)

Cardiac Cells

6.

The "potent" in pluripotency means what?

a)

Super Effective

b)

Highly Concentrated

c)

Many Potentials

d)

Strong Performance

7.

Are pluripotent stem cells "specialized"?

a)

Yes

b)

No

c)

Maybe

8.

"____ Factors" are needed to reprogram an adult somatic cell into an iPSC

a)

Transduction

b)

Growth

c)

Cytokine

d)

Transcription

9.

The first therapeutic dose of iPSC derived material was for treatment of what condition?

a)

Diabetes Type 1

b)

Diabetes Type 2

c)

Skin graft from burn wounds

d)

Macular Degeneration

10.

What products have you successfully sold to your iPSC accounts?

If you do not have an iPSC account, what products would you start with?

4 lines
11.

In the Stanford Collaboration, MODDE was used to optimize which bioreactor processing parameter alongside initial seeding density?

a)

pH

b)

Dissolved Oxygen

c)

Agitation

d)

Temperature

12.

A perfusion setup was used in the AMBR250/Univessel 2L, True or False?

a)

True

b)

False

13.

What is the benefit of perfusion based cell culture?

4 lines
14.

Describe briefly how the AMBR250 and Univessel 2L were used or relate to one another in the Stanford collab.

4 lines
15.

"Karyotyping" is performed (and was performed in the Stanford collab), to check for abnormalities in what part of the iPSC cells?

a)

Nucleus

b)

RNA

c)

DNA

d)

Chromosomes